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Large language models (LLMs) are increasingly adopted in clinical decision support, yet aligning them with the multifaceted reasoning pathways of real-world medicine remains a major challenge. Using more than 8,000 infertility treatment…

Machine Learning · Computer Science 2025-11-25 Dou Liu , Ying Long , Sophia Zuoqiu , Kaipeng Xie , Runze Yang , Di Liu , Kang Li , Yiting Lin , Hanyi Liu , Rong Yin , Tian Tang

Large Language Models (LLMs) are typically aligned with human values using preference data or predefined principles such as helpfulness, honesty, and harmlessness. However, as AI systems progress toward Artificial General Intelligence (AGI)…

Computation and Language · Computer Science 2025-12-08 Panatchakorn Anantaprayoon , Nataliia Babina , Jad Tarifi , Nima Asgharbeygi

As large language models (LLMs) increasingly act as autonomous agents in markets and organizations, their behavior in strategic environments becomes economically consequential. We document that off-the-shelf LLM agents exhibit systematic…

General Economics · Economics 2026-03-16 Wei Lu , Amit Dhanda , Daniel L. Chen , Christian B. Hansen

Combinatorial optimization (CO) problems, central to decision-making scenarios like logistics and manufacturing, are traditionally solved using problem-specific algorithms requiring significant domain expertise. While large language models…

Artificial Intelligence · Computer Science 2025-09-24 Xia Jiang , Yaoxin Wu , Minshuo Li , Zhiguang Cao , Yingqian Zhang

Optimization methods are widely employed in deep learning to identify and mitigate undesired model responses. While gradient-based techniques have proven effective for image models, their application to language models is hindered by the…

Machine Learning · Computer Science 2025-02-18 Zi Wang , Divyam Anshumaan , Ashish Hooda , Yudong Chen , Somesh Jha

Advancements in large language models (LLMs) have demonstrated remarkable capabilities across a diverse range of applications. These models excel in generating text completions that are contextually coherent and cover an extensive array of…

Computation and Language · Computer Science 2024-01-22 Bradley Butcher

The alignment of language models~(LMs) with human preferences is critical for building reliable AI systems. The problem is typically framed as optimizing an LM policy to maximize the expected reward that reflects human preferences.…

Artificial Intelligence · Computer Science 2026-01-28 Zetian Sun , Dongfang Li , Xuhui Chen , Baotian Hu , Min Zhang

Large language models (LLMs) exhibit hallucinations (i.e., unfaithful or nonsensical information) when serving as AI assistants in various domains. Since hallucinations always come with truthful content in the LLM responses, previous…

Computation and Language · Computer Science 2025-03-05 Yuzhe Gu , Wenwei Zhang , Chengqi Lyu , Dahua Lin , Kai Chen

Aligning the output of Large Language Models (LLMs) with human preferences (e.g., by means of reinforcement learning with human feedback, or RLHF) is essential for ensuring their effectiveness in real-world scenarios. Despite significant…

Artificial Intelligence · Computer Science 2024-10-23 Pietro Bernardelle , Gianluca Demartini

Generating long, coherent text remains a challenge for large language models (LLMs), as they lack hierarchical planning and structured organization in discourse generation. We introduce Structural Alignment, a novel method that aligns LLMs…

Computation and Language · Computer Science 2026-02-04 Zae Myung Kim , Anand Ramachandran , Farideh Tavazoee , Joo-Kyung Kim , Oleg Rokhlenko , Dongyeop Kang

While large-scale unsupervised language models (LMs) learn broad world knowledge and some reasoning skills, achieving precise control of their behavior is difficult due to the completely unsupervised nature of their training. Existing…

Machine Learning · Computer Science 2024-07-31 Rafael Rafailov , Archit Sharma , Eric Mitchell , Stefano Ermon , Christopher D. Manning , Chelsea Finn

As Large Language Models (LLMs) become increasingly integrated into real-world applications, ensuring their outputs align with human values and safety standards has become critical. The field has developed diverse alignment approaches…

Large language models (LLMs) are fine-tuned using human comparison data with Reinforcement Learning from Human Feedback (RLHF) methods to make them better aligned with users' preferences. In contrast to LLMs, human preference learning has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Bram Wallace , Meihua Dang , Rafael Rafailov , Linqi Zhou , Aaron Lou , Senthil Purushwalkam , Stefano Ermon , Caiming Xiong , Shafiq Joty , Nikhil Naik

Aligning large language models (LLMs) with human preferences usually requires fine-tuning methods such as RLHF and DPO. These methods directly optimize the model parameters, so they cannot be used in test-time to improve model performance,…

Machine Learning · Computer Science 2025-07-04 Xinnan Zhang , Chenliang Li , Siliang Zeng , Jiaxiang Li , Zhongruo Wang , Kaixiang Lin , Songtao Lu , Alfredo Garcia , Mingyi Hong

Large Language Models (LLMs) have shown impressive reasoning capabilities in well-defined problems with clear solutions, such as mathematics and coding. However, they still struggle with complex real-world scenarios like business…

Computation and Language · Computer Science 2025-05-29 Xiaoqian Liu , Ke Wang , Yongbin Li , Yuchuan Wu , Wentao Ma , Aobo Kong , Fei Huang , Jianbin Jiao , Junge Zhang

Large language models (LLMs) have revolutionized natural language processing (NLP) by excelling at understanding and generating human-like text. However, their widespread deployment can be prohibitively expensive. SortedNet is a recent…

Computation and Language · Computer Science 2024-02-12 Parsa Kavehzadeh , Mojtaba Valipour , Marzieh Tahaei , Ali Ghodsi , Boxing Chen , Mehdi Rezagholizadeh

Large Language Models (LLMs) deliver state-of-the-art performance across many tasks but impose high computational and memory costs, limiting their deployment in resource-constrained or real-time settings. To address this, we propose…

Computation and Language · Computer Science 2025-11-14 Nikunj Gupta , Bill Guo , Rajgopal Kannan , Viktor K. Prasanna

Our goal is to enable large language models (LLMs) to balance multiple human preference dimensions; such as helpfulness, safety, and verbosity, through principled and controllable alignment. Existing preference optimization methods,…

Machine Learning · Computer Science 2026-02-03 Mete Erdogan

Training and fine-tuning large language models (LLMs) come with challenges related to memory and computational requirements due to the increasing size of the model weights and the optimizer states. Various techniques have been developed to…

Machine Learning · Computer Science 2025-12-09 Yehonathan Refael , Jonathan Svirsky , Boris Shustin , Wasim Huleihel , Ofir Lindenbaum

Recent large language models (LLMs) have demonstrated strong reasoning capabilities that benefits from online reinforcement learning (RL). These capabilities have primarily been demonstrated within the left-to-right autoregressive (AR)…

Computation and Language · Computer Science 2025-06-04 Siyan Zhao , Devaansh Gupta , Qinqing Zheng , Aditya Grover
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