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Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

While Large Language Models (LLMs) are increasingly deployed for table-related tasks, the internal mechanisms enabling them to process linearized two-dimensional structured tables remain opaque. In this work, we investigate the process of…

Computation and Language · Computer Science 2026-02-10 Xuanliang Zhang , Dingzirui Wang , Keyan Xu , Qingfu Zhu , Wanxiang Che

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

The rise of large language models (LLMs) has marked a pivotal shift in the field of natural language processing (NLP). LLMs have revolutionized a multitude of domains, and they have made a significant impact in the medical field. Large…

The advancement of Multimodal Large Language Models (MLLMs) has greatly accelerated the development of applications in understanding integrated texts and images. Recent works leverage image-caption datasets to train MLLMs, achieving…

Computation and Language · Computer Science 2024-11-22 Mingxu Tao , Quzhe Huang , Kun Xu , Liwei Chen , Yansong Feng , Dongyan Zhao

Accurate estimation of postmenstrual age (PMA) at scan is crucial for assessing neonatal development and health. While deep learning models have achieved high accuracy in predicting PMA from brain MRI, they often function as black boxes,…

Artificial Intelligence · Computer Science 2025-08-05 Qifan Chen , Jin Cui , Cindy Duan , Yushuo Han , Yifei Shi

Large language models (LLMs) demonstrate extraordinary abilities in a wide range of natural language processing (NLP) tasks. In this paper, we show that, beyond text understanding capability, LLMs are capable of processing text layouts that…

Computation and Language · Computer Science 2024-08-29 Weiming Li , Manni Duan , Dong An , Yan Shao

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

We aim to present a comprehensive overview of the latest advancements in utilizing Large Language Models (LLMs) within the healthcare sector, emphasizing their transformative impact across various medical domains. LLMs have become pivotal…

Computation and Language · Computer Science 2026-04-07 Ummara Mumtaz , Awais Ahmed , Summaya Mumtaz

Large Language Models (LLMs) are known to exhibit social, demographic, and gender biases, often as a consequence of the data on which they are trained. In this work, we adopt a mechanistic interpretability approach to analyze how such…

Computation and Language · Computer Science 2025-06-09 Bhavik Chandna , Zubair Bashir , Procheta Sen

Large Language Models (LLMs) have become a pivotal research area, potentially making beneficial contributions in fields like healthcare where they can streamline automated billing and decision support. However, the frequent use of…

Computation and Language · Computer Science 2024-06-10 Simon A. Lee , Timothy Lindsey

Locating and editing knowledge in large language models (LLMs) is crucial for enhancing their accuracy, safety, and inference rationale. We introduce ``concept editing'', an innovative variation of knowledge editing that uncovers…

Computation and Language · Computer Science 2024-08-23 Nura Aljaafari , Danilo S. Carvalho , André Freitas

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Large Language Models (LLMs) have recently demonstrated remarkable performance in general tasks across various fields. However, their effectiveness within specific domains such as drug development remains challenges. To solve these…

Artificial Intelligence · Computer Science 2024-10-16 Tengfei Ma , Xuan Lin , Tianle Li , Chaoyi Li , Long Chen , Peng Zhou , Xibao Cai , Xinyu Yang , Daojian Zeng , Dongsheng Cao , Xiangxiang Zeng

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

There is increasing interest in the application large language models (LLMs) to the medical field, in part because of their impressive performance on medical exam questions. While promising, exam questions do not reflect the complexity of…

Understanding molecules is key to understanding organisms and driving advances in drug discovery, requiring interdisciplinary knowledge across chemistry and biology. Although large molecular language models have achieved notable success in…

Machine Learning · Computer Science 2025-10-03 Dongki Kim , Wonbin Lee , Sung Ju Hwang