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Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However,…

Foundation models (FM) have transformed computational pathology but remain computationally prohibitive for clinical deployment due to their massive parameter counts and high-magnification processing requirements. Here, we introduce XMAG, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Anil V. Parwani , Muhammad Khalid Khan Niazi

The development of computer vision solutions for gigapixel images in digital pathology is hampered by significant computational limitations due to the large size of whole slide images. In particular, digitizing biopsies at high resolutions…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Rocío del Amor , Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

Deploying medical image segmentation models in routine clinical workflows is often constrained by on-premises infrastructure, where computational resources are fixed and cloud-based inference may be restricted by governance and security…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Qizhen Lan , Aaron Choi , Jun Ma , Bo Wang , Zhaogming Zhao , Xiaoqian Jiang , Yu-Chun Hsu

Despite the remarkable performance of large-scale generative models in open-domain conversation, they are known to be less practical for building real-time conversation systems due to high latency. On the other hand, retrieval models could…

Computation and Language · Computer Science 2021-09-01 Beomsu Kim , Seokjun Seo , Seungju Han , Enkhbayar Erdenee , Buru Chang

Recent advances in large-scale visual representation learning have significantly improved performance in plant species and plant disease recognition tasks. However, state-of-the-art models, often based on high-capacity vision transformers…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Ilyass Moummad , Reda Bensaid , Kawtar Zaher , Hervé Goëau , Jean-Christophe Lombardo , Joseph Salmon , Pierre Bonnet , Alexis Joly

Although more layers and more parameters generally improve the accuracy of the models, such big models generally have high computational complexity and require big memory, which exceed the capacity of small devices for inference and incurs…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-15 Ji Liu , Daxiang Dong , Xi Wang , An Qin , Xingjian Li , Patrick Valduriez , Dejing Dou , Dianhai Yu

In recent years, the advent of foundation models (FM) for digital pathology has relied heavily on scaling the pre-training datasets and the model size, yielding large and powerful models. While it resulted in improving the performance on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Alexandre Filiot , Nicolas Dop , Oussama Tchita , Auriane Riou , Rémy Dubois , Thomas Peeters , Daria Valter , Marin Scalbert , Charlie Saillard , Geneviève Robin , Antoine Olivier

Dataset distillation aims to distill the knowledge of a large-scale real dataset into small yet informative synthetic data such that a model trained on it performs as well as a model trained on the full dataset. Despite recent progress,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ahmad Sajedi , Samir Khaki , Lucy Z. Liu , Ehsan Amjadian , Yuri A. Lawryshyn , Konstantinos N. Plataniotis

Pathology foundation models (FMs) have driven significant progress in computational pathology. However, these high-performing models can easily exceed a billion parameters and produce high-dimensional embeddings, thus limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Christian Grashei , Christian Brechenmacher , Rao Muhammad Umer , Jingsong Liu , Carsten Marr , Ewa Szczurek , Peter J. Schüffler

Multimodal learning aims to leverage information from diverse data modalities to achieve more comprehensive performance. However, conventional multimodal models often suffer from modality imbalance, where one or a few modalities dominate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mohammed Rakib , Arunkumar Bagavathi

Model compression is critical for deploying deep learning models on resource-constrained devices. We introduce a novel method enhancing knowledge distillation with integrated gradients (IG) as a data augmentation strategy. Our approach…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David E. Hernandez , Jose Chang , Torbjörn E. M. Nordling

Large vision Transformers (ViTs) driven by self-supervised pre-training mechanisms achieved unprecedented progress. Lightweight ViT models limited by the model capacity, however, benefit little from those pre-training mechanisms. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Wei Huang , Zhiliang Peng , Li Dong , Furu Wei , Jianbin Jiao , Qixiang Ye

Large language models (LLMs) excel at clinical information extraction but their computational demands limit practical deployment. Knowledge distillation--the process of transferring knowledge from larger to smaller models--offers a…

Computation and Language · Computer Science 2025-01-03 Karthik S. Vedula , Annika Gupta , Akshay Swaminathan , Ivan Lopez , Suhana Bedi , Nigam H. Shah

Knowledge distillation is one of the most popular and effective techniques for knowledge transfer, model compression and semi-supervised learning. Most existing distillation approaches require the access to original or augmented training…

Machine Learning · Computer Science 2020-12-11 Liangchen Luo , Mark Sandler , Zi Lin , Andrey Zhmoginov , Andrew Howard

The deployment of foundation models for medical imaging has demonstrated considerable success. However, their training overheads associated with downstream tasks remain substantial due to the size of the image encoders employed, and the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Chengxi Zeng , Yuxuan Jiang , Fan Zhang , Alberto Gambaruto , Tilo Burghardt

Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…

Current scaling laws for visual AI models focus predominantly on large-scale pretraining, leaving a critical gap in understanding how performance scales for data-constrained downstream tasks. To address this limitation, this paper…

Machine Learning · Computer Science 2025-04-21 Wenxuan Yang , Qingqu Wei , Chenxi Ma , Weimin Tan , Bo Yan

Large Genomic Foundation Models have recently achieved remarkable results and in-vivo translation capabilities. However these models quickly grow to over a few Billion of parameters and are expensive to run when compute is limited. To…

Machine Learning · Computer Science 2026-04-13 Rasched Haidari , Sam Martin , Maxime Allard

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

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