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Communication technologies like voice over IP operate under constrained real-time conditions, with voice packets being subject to delays and losses from the network. In such cases, the packet loss concealment (PLC) algorithm reconstructs…

Sound · Computer Science 2021-07-09 Santiago Pascual , Joan Serrà , Jordi Pons

Deep neural networks are powerful tools for biomedical image segmentation. These models are often trained with heavy supervision, relying on pairs of images and corresponding voxel-level labels. However, obtaining segmentations of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-30 Evan M. Yu , Juan Eugenio Iglesias , Adrian V. Dalca , Mert R. Sabuncu

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

Protein inverse folding aims to identify viable amino acid sequences that can fold into given protein structures, enabling the design of novel proteins with desired functions for applications in drug discovery, enzyme engineering, and…

Quantitative Methods · Quantitative Biology 2024-11-05 Taoyu Wu , Yu Guang Wang , Yiqing Shen

Learning informative representations of phylogenetic tree structures is essential for analyzing evolutionary relationships. Classical distance-based methods have been widely used to project phylogenetic trees into Euclidean space, but they…

Machine Learning · Statistics 2025-02-10 Tianyu Xie , Harry Richman , Jiansi Gao , Frederick A. Matsen , Cheng Zhang

Protein representation learning methods have shown great potential to yield useful representation for many downstream tasks, especially on protein classification. Moreover, a few recent studies have shown great promise in addressing…

Machine Learning · Computer Science 2023-04-11 Can Chen , Jingbo Zhou , Fan Wang , Xue Liu , Dejing Dou

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Counterfactual explanations (CEs) aim to enhance the interpretability of machine learning models by illustrating how alterations in input features would affect the resulting predictions. Common CE approaches require an additional model and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Matan Atad , David Schinz , Hendrik Moeller , Robert Graf , Benedikt Wiestler , Daniel Rueckert , Nassir Navab , Jan S. Kirschke , Matthias Keicher

This study introduces a compositional autoencoder (CAE) framework designed to disentangle the complex interplay between genotypic and environmental factors in high-dimensional phenotype data to improve trait prediction in plant breeding and…

Recent breakthroughs in video autoencoders (Video AEs) have advanced video generation, but existing methods fail to efficiently model spatio-temporal redundancies in dynamics, resulting in suboptimal compression factors. This shortfall…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Huaize Liu , Wenzhang Sun , Qiyuan Zhang , Donglin Di , Biao Gong , Hao Li , Chen Wei , Changqing Zou

Variational autoencoders (VAEs) employ Bayesian inference to interpret sensory inputs, mirroring processes that occur in primate vision across both ventral (Higgins et al., 2021) and dorsal (Vafaii et al., 2023) pathways. Despite their…

Machine Learning · Computer Science 2024-12-10 Hadi Vafaii , Dekel Galor , Jacob L. Yates

Given the complex geometry of white matter streamlines, Autoencoders have been proposed as a dimension-reduction tool to simplify the analysis streamlines in a low-dimensional latent spaces. However, despite these recent successes, the…

Machine Learning · Statistics 2023-11-21 Andrew Lizarraga , Brandon Taraku , Edouardo Honig , Ying Nian Wu , Shantanu H. Joshi

Combining neuroimaging datasets from multiple sites and scanners can help increase statistical power and thus provide greater insight into subtle neuroanatomical effects. However, site-specific effects pose a challenge by potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ayodeji Ijishakin , Ana Lawry Aguila , Elizabeth Levitis , Ahmed Abdulaal , Andre Altmann , James Cole

Variational Autoencoders (VAEs) are well-established as a principled approach to probabilistic unsupervised learning with neural networks. Typically, an encoder network defines the parameters of a Gaussian distributed latent space from…

Machine Learning · Computer Science 2025-05-16 Alan Jeffares , Liyuan Liu

The need for interpretable models has fostered the development of self-explainable classifiers. Prior approaches are either based on multi-stage optimization schemes, impacting the predictive performance of the model, or produce…

Advances in deep learning have opened an era of abundant and accurate predicted protein structures; however, similar progress in protein ensembles has remained elusive. This review highlights several recent research directions towards…

Biomolecules · Quantitative Biology 2025-09-23 Bowen Jing , Bonnie Berger , Tommi Jaakkola

Despite recent successes in synthesizing faces and bedrooms, existing generative models struggle to capture more complex image types, potentially due to the oversimplification of their latent space constructions. To tackle this issue,…

Machine Learning · Computer Science 2018-03-13 Wenling Shang , Kihyuk Sohn , Yuandong Tian

Learning 3D representation plays a critical role in masked autoencoder (MAE) based pre-training methods for point cloud, including single-modal and cross-modal based MAE. Specifically, although cross-modal MAE methods learn strong 3D…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Yaohua Zha , Huizhen Ji , Jinmin Li , Rongsheng Li , Tao Dai , Bin Chen , Zhi Wang , Shu-Tao Xia

We propose a new concept of rateless auto-encoders (RL-AEs) that enable a flexible latent dimensionality, which can be seamlessly adjusted for varying distortion and dimensionality requirements. In the proposed RL-AEs, instead of a…

Machine Learning · Computer Science 2020-05-07 Toshiaki Koike-Akino , Ye Wang

Early detection of Barrett's Esophagus (BE), the only known precursor to Esophageal adenocarcinoma (EAC), is crucial for effectively preventing and treating esophageal cancer. In this work, we investigate the potential of geometric…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Vivien van Veldhuizen , Sharvaree Vadgama , Onno J. de Boer , Sybren Meijer , Erik J. Bekkers
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