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Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Large language models (LLMs) have revolutionized natural language processing (NLP) by excelling at understanding and generating human-like text. However, their widespread deployment can be prohibitively expensive. SortedNet is a recent…

Computation and Language · Computer Science 2024-02-12 Parsa Kavehzadeh , Mojtaba Valipour , Marzieh Tahaei , Ali Ghodsi , Boxing Chen , Mehdi Rezagholizadeh

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by…

Large language models (LLMs) have exhibited remarkable capabilities across various domains and tasks, pushing the boundaries of our knowledge in learning and cognition. The latest model, OpenAI's o1, stands out as the first LLM with an…

Computation and Language · Computer Science 2024-09-24 Yunfei Xie , Juncheng Wu , Haoqin Tu , Siwei Yang , Bingchen Zhao , Yongshuo Zong , Qiao Jin , Cihang Xie , Yuyin Zhou

Developing the required technology to assist medical experts in their everyday activities is currently a hot topic in the Artificial Intelligence research field. Thus, a number of large language models (LLMs) and automated benchmarks have…

Computation and Language · Computer Science 2023-12-04 Iakes Goenaga , Aitziber Atutxa , Koldo Gojenola , Maite Oronoz , Rodrigo Agerri

Large language models (LLMs) are increasingly explored for clinical decision support, yet most evaluations are conducted in English, leaving their reliability in other languages uncertain. Here we evaluate the impact of prompting language…

Computation and Language · Computer Science 2026-05-20 Adrien Bazoge , Josselin Corvellec , Sofiane Djillali Sid-Ahmed , Pierre-Antoine Gourraud

Large language models (LLMs) have shown considerable promise in clinical natural language processing, yet few domain-specific datasets exist to rigorously evaluate their performance on radiology tasks. In this work, we introduce an…

Computation and Language · Computer Science 2025-11-18 Namu Park , Giridhar Kaushik Ramachandran , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen , Martin Gunn

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Preparing an oral case presentation (OCP) is a crucial skill for medical students, requiring clear communication of patient information, clinical findings, and treatment plans. However, inconsistent student participation and limited…

Human-Computer Interaction · Computer Science 2026-01-28 Yang Ouyang , Yuansong Xu , Chang Jiang , Yifan Jin , Haoran Jiang , Quan Li

Objective: Function is increasingly recognized as an important indicator of whole-person health. This study evaluates the ability of publicly available large language models (LLMs) to accurately identify the presence of functioning…

Computation and Language · Computer Science 2023-12-19 Tuan Dung Le , Thanh Duong , Thanh Thieu

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

This study evaluates the capacity of large language models (LLMs) to generate structured clinical consultation templates for electronic consultation. Using 145 expert-crafted templates developed and routinely used by Stanford's eConsult…

Large language models (LLMs) have achieved great success in medical question answering and clinical decision-making, promoting the efficiency and popularization of the personalized virtual doctor in society. However, the traditional…

Computation and Language · Computer Science 2025-09-23 Jianbin Zhang , Yulin Zhu , Wai Lun Lo , Richard Tai-Chiu Hsung , Harris Sik-Ho Tsang , Kai Zhou

Objective Structured Clinical Examinations (OSCEs) are widely used to assess medical students' communication skills, but scoring interview-based assessments is time-consuming and potentially subject to human bias. This study explored the…

Computation and Language · Computer Science 2025-05-16 Jadon Geathers , Yann Hicke , Colleen Chan , Niroop Rajashekar , Justin Sewell , Susannah Cornes , Rene F. Kizilcec , Dennis Shung

Since the emergence of Large Language Models (LLMs), the challenge of effectively leveraging their potential in healthcare has taken center stage. A critical barrier to using LLMs for extracting insights from unstructured clinical notes…

Artificial Intelligence · Computer Science 2024-12-04 Nader Karayanni , Aya Awwad , Chein-Lien Hsiao , Surish P Shanmugam

Structured outputs are essential for large language models (LLMs) in critical applications like agents and information extraction. Despite their capabilities, LLMs often generate outputs that deviate from predefined schemas, significantly…

Computation and Language · Computer Science 2025-05-08 Darren Yow-Bang Wang , Zhengyuan Shen , Soumya Smruti Mishra , Zhichao Xu , Yifei Teng , Haibo Ding

This position paper examines how large language models (LLMs) can support thematic analysis of unstructured clinical transcripts, a widely used but resource-intensive method for uncovering patterns in patient and provider narratives. We…

Computation and Language · Computer Science 2025-09-30 Seungjun Yi , Joakim Nguyen , Terence Lim , Andrew Well , Joseph Skrovan , Mehak Beri , YongGeon Lee , Kavita Radhakrishnan , Liu Leqi , Mia Markey , Ying Ding

Background: Social support (SS) and social isolation (SI) are social determinants of health (SDOH) associated with psychiatric outcomes. In electronic health records (EHRs), individual-level SS/SI is typically documented as narrative…

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

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