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Medical image segmentation requires consensus ground truth segmentations to be derived from multiple expert annotations. A novel approach is proposed that obtains consensus segmentations from experts using graph cuts (GC) and semi…

Computer Vision and Pattern Recognition · Computer Science 2018-05-22 Dwarikanath Mahapatra

A major challenge in the segmentation of medical images is the large inter- and intra-observer variability in annotations provided by multiple experts. To address this challenge, we propose a novel method for multi-expert prediction using…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Tomer Amit , Shmuel Shichrur , Tal Shaharabany , Lior Wolf

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Classifiers for medical image analysis are often trained with a single consensus label, based on combining labels given by experts or crowds. However, disagreement between annotators may be informative, and thus removing it may not be the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-20 Veronika Cheplygina , Josien P. W. Pluim

Collective intelligence from multiple medical experts consistently surpasses individual expertise in clinical diagnosis, particularly for ambiguous medical image segmentation tasks involving unclear tissue boundaries or pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Mingzhou Jiang , Jiaying Zhou , Junde Wu , Tianyang Wang , Yueming Jin , Min Xu

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

Multi-rater medical image segmentation captures the inherent ambiguity of clinical interpretation, where diagnostic boundaries vary across experts and imaging devices. Existing approaches often reduce this diversity to consensus labels or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Sanaz Karimijafarbigloo , Armin Khosravi , Alireza Kheyrkhah , Reza Azad , Mauricio Reyes , Dorit Merhof

Collective insights from a group of experts have always proven to outperform an individual's best diagnostic for clinical tasks. For the task of medical image segmentation, existing research on AI-based alternatives focuses more on…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Aimon Rahman , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Lu Wang , Dong Guo , Guotai Wang , Shaoting Zhang

The task of image segmentation is inherently noisy due to ambiguities regarding the exact location of boundaries between anatomical structures. We argue that this information can be extracted from the expert annotations at no extra cost,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Mobarakol Islam , Ben Glocker

Recent years have seen increasing use of supervised learning methods for segmentation tasks. However, the predictive performance of these algorithms depends on the quality of labels. This problem is particularly pertinent in the medical…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Le Zhang , Ryutaro Tanno , Mou-Cheng Xu , Chen Jin , Joseph Jacob , Olga Ciccarelli , Frederik Barkhof , Daniel C. Alexander

In medical image segmentation, it is often necessary to collect opinions from multiple experts to make the final decision. This clinical routine helps to mitigate individual bias. But when data is multiply annotated, standard deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Junde Wu , Huihui Fang , Yehui Yang , Yuanpei Liu , Jing Gao , Lixin Duan , Weihua Yang , Yanwu Xu

Medical image annotation is a major hurdle for developing precise and robust machine learning models. Annotation is expensive, time-consuming, and often requires expert knowledge, particularly in the medical field. Here, we suggest using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Holger R Roth , Dong Yang , Ziyue Xu , Xiaosong Wang , Daguang Xu

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

A primary challenge in semi-supervised learning (SSL) for segmentation is the confirmation bias from noisy pseudo-labels, which destabilizes training and degrades performance. We propose Inconsistency Masks (IM), a framework that reframes…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Michael R. H. Vorndran , Bernhard F. Roeck

In clinical medicine, precise image segmentation can provide substantial support to clinicians. However, obtaining high-quality segmentation typically demands extensive pixel-level annotations, which are labor-intensive and expensive.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Tao Wang , Xinlin Zhang , Zhenxuan Zhang , Yuanbo Zhou , Yuanbin Chen , Longxuan Zhao , Chaohui Xu , Shun Chen , Guang Yang , Tong Tong

Medical image segmentation (MIS) plays an instrumental role in medical image analysis, where considerable effort has been devoted to automating the process. Currently, mainstream MIS approaches are based on deep neural networks (DNNs),…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Binyan Hu , A. K. Qin

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen

Medical image segmentation annotations suffer from inter- and intra-observer variations even among experts due to intrinsic differences in human annotators and ambiguous boundaries. Leveraging a collection of annotators' opinions for an…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Zahra Mirikharaji , Kumar Abhishek , Saeed Izadi , Ghassan Hamarneh

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li
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