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The Early diagnosis and treatment of depression is essential for effective treatment. Depression, while being one of the most common mental illnesses, is still poorly understood in both research and clinical practice. Among different…
Current approaches to detecting depression and anxiety from speech primarily rely on machine learning techniques that utilize hand-engineered paralinguistic features and related acoustic descriptors derived from time- and frequency-domain…
Objective: To develop multisensor-wearable-device sleep monitoring algorithms that are robust to health disruptions affecting sleep patterns. Methods: We develop an unsupervised transfer learning algorithm based on a multivariate hidden…
Depression is a complex mental disorder characterized by a diverse range of observable and measurable indicators that go beyond traditional subjective assessments. Recent research has increasingly focused on objective, passive, and…
Background: Black-box skepticism is one of the main hindrances impeding deep-learning-based automatic sleep scoring from being used in clinical environments. Methods: Towards interpretability, this work proposes a sequence-to-sequence…
Continuous monitoring of behavior and physiology via wearable devices offers a novel, objective method for the early detection of worsening depression and anxiety. In this study, we present an explainable anomaly detection framework that…
Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…
Sleep and mental health are highly related concepts, and it is an important research and clinical priority to understand their interactions. In-bed sensors using ballistocardiography provide the possibility of unobtrusive measurements of…
One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…
Depression is one of the most common mental disorders, which imposes heavy negative impacts on one's daily life. Diagnosing depression based on the interview is usually in the form of questions and answers. In this process, the audio…
Accurate sleep stage classification is significant for sleep health assessment. In recent years, several machine-learning based sleep staging algorithms have been developed , and in particular, deep-learning based algorithms have achieved…
Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…
Understanding how human health changes over time, and why responses to interventions vary between individuals, remains a central challenge in medicine. Here we present HealthFormer, a decoder-only transformer that models the human…
The detection of depression in social media posts is crucial due to the increasing prevalence of mental health issues. Traditional machine learning algorithms often fail to capture intricate textual patterns, limiting their effectiveness in…
Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of…
Almost 50% depression patients face the risk of going into relapse. The risk increases to 80% after the second episode of depression. Although, depression detection from social media has attained considerable attention, depression relapse…
Sleep constitutes a key indicator of human health, performance, and quality of life. Sleep deprivation has long been related to the onset, development, and worsening of several mental and metabolic disorders, constituting an essential…
We use autoregressive hidden Markov models and a time-frequency approach to create meaningful quantitative descriptions of behavioral characteristics of cerebellar ataxias from wearable inertial sensor data gathered during movement.…
Alzheimer's disease (AD) is a neurodegenerative disorder with no known cure that affects tens of millions of people worldwide. Early detection of AD is critical for timely intervention to halt or slow the progression of the disease. In this…
Automated depression screening and diagnosis is a highly relevant problem today. There are a number of limitations of the traditional depression detection methods, namely, high dependence on clinicians and biased self-reporting. In recent…