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Most domains of science are experiencing a paradigm shift due to the advent of a new generation of instruments and detectors which produce data and data streams at an unprecedented rate. The scientific exploitation of these data, namely…

Instrumentation and Methods for Astrophysics · Physics 2024-09-06 Massimo Brescia , Giuseppe Angora

Data-driven artificial intelligence models fed with published scientific findings have been used to create powerful prediction engines for scientific and technological advance, such as the discovery of novel materials with desired…

Artificial Intelligence · Computer Science 2021-04-13 Jamshid Sourati , James Evans

Generative AI is rapidly transforming medical imaging and text analysis, offering immense potential for enhanced diagnosis and personalized care. However, this transformative technology raises crucial ethical, societal, and legal questions.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Onyekachukwu R. Okonji , Kamol Yunusov , Bonnie Gordon

The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that…

Artificial Intelligence · Computer Science 2025-10-20 Ed Li , Junyu Ren , Xintian Pan , Cat Yan , Chuanhao Li , Dirk Bergemann , Zhuoran Yang

The disruptive potential of AI systems roots in the emergence of big data. Yet, a significant portion is scattered and locked in data silos, leaving its potential untapped. Federated Machine Learning is a novel AI paradigm enabling the…

Artificial Intelligence · Computer Science 2023-05-02 Tobias Müller , Milena Zahn , Florian Matthes

As AI adoption expands across human society, the problem of aligning AI models to match human preferences remains a grand challenge. Currently, the AI alignment field is deeply divided between behavioral and representational approaches,…

Computers and Society · Computer Science 2025-08-12 Ben Y. Reis , William La Cava

Generative AI is spreading rapidly, creating significant social and economic value while also raising concerns about its high energy use and environmental sustainability. While prior studies have predominantly focused on the…

Computers and Society · Computer Science 2026-02-12 Min-Kyu Kim , Tae-An Yoo , Ji-Bum Chung

This paper presents SYMBIOSIS, an AI-powered framework and platform designed to make Systems Thinking accessible for addressing societal challenges and unlock paths for leveraging systems thinking frameworks to improve AI systems. The…

Computers and Society · Computer Science 2025-03-11 Sameer Sethi , Donald Martin , Emmanuel Klu

The potential of AI researchers in scientific discovery remains largely untapped. Over the past decade, AI for Science (AI4Science) publications in 145 Nature Index journals have increased fifteen-fold, yet they still account for less than…

Computers and Society · Computer Science 2025-09-24 Hengjie Yu , Shuya Liu , Haiyun Yang , Yuping Yan , Maozhen Qu , Yaochu Jin

In recent years the development of artificial intelligence (AI) systems for automated medical image analysis has gained enormous momentum. At the same time, a large body of work has shown that AI systems can systematically and unfairly…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 María Agustina Ricci Lara , Candelaria Mosquera , Enzo Ferrante , Rodrigo Echeveste

Advances in robotic automation, high-performance computing (HPC), and artificial intelligence (AI) encourage us to conceive of science factories: large, general-purpose computation- and AI-enabled self-driving laboratories (SDLs) with the…

Much attention and concern has been raised recently about bias and the use of machine learning algorithms in healthcare, especially as it relates to perpetuating racial discrimination and health disparities. Following an initial system…

Machine Learning · Computer Science 2023-05-24 Jill A. Kuhlberg , Irene Headen , Ellis A. Ballard , Donald Martin

Human intelligence, the most evident and accessible form of source of reasoning, hosted by biological hardware, has evolved and been refined over thousands of years, positioning itself today to create new artificial forms and preparing to…

Artificial Intelligence · Computer Science 2025-12-09 Suayb S. Arslan

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…

Quantitative Methods · Quantitative Biology 2022-06-22 Sean T. Vittadello , Michael P. H. Stumpf

In a post-ChatGPT world, this paper explores the potential of leveraging scalable artificial intelligence for scientific discovery. We propose that scaling up artificial intelligence on high-performance computing platforms is essential to…

Machine Learning · Computer Science 2024-06-27 Wesley Brewer , Aditya Kashi , Sajal Dash , Aristeidis Tsaris , Junqi Yin , Mallikarjun Shankar , Feiyi Wang

Epistemic AI accelerates biomedical discovery by finding hidden connections in the network of biomedical knowledge. The Epistemic AI web-based software platform embodies the concept of knowledge mapping, an interactive process that relies…

Artificial Intelligence · Computer Science 2022-04-04 Da Chen Emily Koo , Heather Bowling , Kenneth Ashworth , David J. Heeger , Stefano Pacifico

Problems of cooperation--in which agents seek ways to jointly improve their welfare--are ubiquitous and important. They can be found at scales ranging from our daily routines--such as driving on highways, scheduling meetings, and working…

Artificial Intelligence · Computer Science 2020-12-17 Allan Dafoe , Edward Hughes , Yoram Bachrach , Tantum Collins , Kevin R. McKee , Joel Z. Leibo , Kate Larson , Thore Graepel

Despite substantial potential to transform bioscience, medicine, and bioengineering, whole-cell models remain elusive. One of the biggest challenges to whole-cell models is assembling the large and diverse array of data needed to model an…

Quantitative Methods · Quantitative Biology 2021-05-25 Yin Hoon Chew , Jonathan R. Karr

Artificial intelligence (AI) is reshaping how research is conceived, conducted, and communicated across fields from chemistry to biomedicine. This commentary examines how AI is transforming the research workflow. AI systems now help…

Artificial Intelligence · Computer Science 2025-11-14 Maksim E. Eren , Dorianis M. Perez

Big medical data poses great challenges to life scientists, clinicians, computer scientists, and engineers. In this paper, a group of life scientists, clinicians, computer scientists and engineers sit together to discuss several fundamental…