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The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…

Other Quantitative Biology · Quantitative Biology 2025-01-24 Himanshu Buckchash , Gyanendra Kumar Verma , Dilip K. Prasad

Artificial intelligence and machine learning are reshaping how we approach scientific discovery, not by replacing established methods but by extending what researchers can probe, predict, and design. In this roadmap we provide a…

Modern scientific discovery increasingly requires coordinating distributed facilities and heterogeneous resources, forcing researchers to act as manual workflow coordinators rather than scientists. Advances in AI leading to AI agents show…

Artificial Intelligence · Computer Science 2025-09-15 Woong Shin , Renan Souza , Daniel Rosendo , Frédéric Suter , Feiyi Wang , Prasanna Balaprakash , Rafael Ferreira da Silva

The convergence of artificial intelligence (AI) and synthetic biology is rapidly accelerating the pace of biological discovery and engineering. AI techniques, such as large language models and biological design tools, are enabling the…

Other Quantitative Biology · Quantitative Biology 2024-05-01 Cindy Vindman , Benjamin Trump , Christopher Cummings , Madison Smith , Alexander J. Titus , Ken Oye , Valentina Prado , Eyup Turmus , Igor Linkov

AI is a magnificent field that directly and profoundly touches on numerous disciplines ranging from philosophy, computer science, engineering, mathematics, decision and data science and economics, to cognitive science, neuroscience and…

Computers and Society · Computer Science 2024-10-16 Simon Kasif

Data Science research is undergoing a revolution fueled by the transformative power of technology, the Internet, and an ever increasing computational capacity. The rate at which sophisticated algorithms can be developed is unprecedented,…

Artificial intelligence (AI) is being increasingly applied to scientific research, but its benefits remain unevenly distributed across different communities and disciplines. While technical challenges such as limited data, fragmented…

Machine Learning · Computer Science 2026-03-17 Georgia Channing , Avijit Ghosh

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

The emergence of "big data" offers unprecedented opportunities for not only accelerating scientific advances but also enabling new modes of discovery. Scientific progress in many disciplines is increasingly enabled by our ability to examine…

Computers and Society · Computer Science 2017-07-03 Vasant G. Honavar , Mark D. Hill , Katherine Yelick

A vast array of transformative technologies developed over the past decade has enabled measurement and perturbation at ever increasing scale, yet our understanding of many systems remains limited by experimental capacity. Overcoming this…

Quantitative Methods · Quantitative Biology 2020-12-25 Brian Cleary , Aviv Regev

Traditionally, cognitive and computer scientists have viewed intelligence solipsistically, as a property of unitary agents devoid of social context. Given the success of contemporary learning algorithms, we argue that the bottleneck in…

Artificial Intelligence · Computer Science 2024-05-28 Edgar A. Duéñez-Guzmán , Suzanne Sadedin , Jane X. Wang , Kevin R. McKee , Joel Z. Leibo

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

The pursuit of advanced polymers for energy technologies, spanning photovoltaics, solid-state batteries, and hydrogen storage, is hindered by fragmented data ecosystems that fail to capture the hierarchical complexity of these materials.…

Soft Condensed Matter · Physics 2025-05-21 Ying Zhao , Guanhua Chen , Jie Liu

Recent advances in machine learning and AI, including Generative AI and LLMs, are disrupting technological innovation, product development, and society as a whole. AI's contribution to technology can come from multiple approaches that…

Artificial Intelligence has proven to be a transformative tool for advancing scientific research across a wide range of disciplines. However, a significant gap still exists between AI and scientific communities, limiting the full potential…

Artificial Intelligence · Computer Science 2025-02-19 Yutong Xie , Yijun Pan , Hua Xu , Qiaozhu Mei

With the advent of large multimodal language models, science is now at a threshold of an AI-based technological transformation. An emerging ecosystem of models and tools aims to support researchers throughout the scientific lifecycle,…

New technologies have the power to revolutionize science. It has happened in the past and is happening again with the emergence of new computational tools, such as artificial intelligence and machine learning. Despite the documented impact…

Computers and Society · Computer Science 2024-02-23 Stefano Bianchini , Moritz Müller , Pierre Pelletier

AI Scaling has traditionally been synonymous with Scaling Up, which builds larger and more powerful models. However, the growing demand for efficiency, adaptability, and collaboration across diverse applications necessitates a broader…

Machine Learning · Computer Science 2025-05-14 Yunke Wang , Yanxi Li , Chang Xu
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