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Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Despite the increasing use of deep learning in medical image segmentation, the limited availability of annotated training data remains a major challenge due to the time-consuming data acquisition and privacy regulations. In the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

This study explores the use of text-prompted MRI image generation with the Stable Diffusion (SD) model to address challenges in acquiring real MRI datasets, such as high costs, limited rare case samples, and privacy concerns. The SD model,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Xinxian Fan , Mengye Lyu

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Medical imaging datasets often suffer from class imbalance and limited availability of pathology-rich cases, which constrains the performance of machine learning models for segmentation, classification, and vision-language tasks. To address…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Fei Tan , Ashok Vardhan Addala , Bruno Astuto Arouche Nunes , Xucheng Zhu , Ravi Soni

Magnetic Resonance (MR) images of different modalities can provide complementary information for clinical diagnosis, but whole modalities are often costly to access. Most existing methods only focus on synthesizing missing images between…

Computer Vision and Pattern Recognition · Computer Science 2020-05-05 Bingyu Xin , Yifan Hu , Yefeng Zheng , Hongen Liao

Current medical vision-language models (VLMs) process volumetric brain MRI using 2D slice-based approximations, fragmenting the spatial context required for accurate neuroradiological interpretation. We developed \textbf{Brain3D}, a staged…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mariano Barone , Francesco Di Serio , Giuseppe Riccio , Antonio Romano , Marco Postiglione , Antonino Ferraro , Vincenzo Moscato

Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard MRI. As a result, current radiotherapy planning employs a…

Deformable image registration is a key task in medical image analysis. The Brain Tumor Sequence Registration challenge (BraTS-Reg) aims at establishing correspondences between pre-operative and follow-up scans of the same patient diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Javid Abderezaei , Aymeric Pionteck , Agamdeep Chopra , Mehmet Kurt

The integration of machine learning in magnetic resonance imaging (MRI), specifically in neuroimaging, is proving to be incredibly effective, leading to better diagnostic accuracy, accelerated image analysis, and data-driven insights, which…

Early diagnosis and accurate segmentation of brain tumors are imperative for successful treatment. Unfortunately, manual segmentation is time consuming, costly and despite extensive human expertise often inaccurate. Here, we present an…

Image and Video Processing · Electrical Eng. & Systems 2019-10-07 Markus Frey , Matthias Nau

Counterfactual generation offers a principled framework for simulating hypothetical changes in medical imaging, with potential applications in understanding disease mechanisms and generating physiologically plausible data. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Pengwei Sun , Wei Peng , Lun Yu Li , Yixin Wang , Kilian M. Pohl

Tumor segmentation plays a critical role in histopathology, but it requires costly, fine-grained image-mask pairs annotated by pathologists. Thus, synthesizing histopathology data to expand the dataset is highly desirable. Previous works…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Hong Liu , Haosen Yang , Evi M. C. Huijben , Mark Schuiveling , Ruisheng Su , Josien P. W. Pluim , Mitko Veta

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

We present a joint graph convolution-image convolution neural network as our submission to the Brain Tumor Segmentation (BraTS) 2021 challenge. We model each brain as a graph composed of distinct image regions, which is initially segmented…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Camillo Saueressig , Adam Berkley , Reshma Munbodh , Ritambhara Singh

Deep intracranial tumors situated in eloquent brain regions controlling vital functions present critical diagnostic challenges. Clinical practice has shifted toward stereotactic biopsy for pathological confirmation before treatment. Yet…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Xinzhe Luo , Shuai Shao , Yan Wang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

To the best of our knowledge, all existing methods that can generate synthetic brain magnetic resonance imaging (MRI) scans for a specific individual require detailed structural or volumetric information about the individual's brain.…

Neurons and Cognition · Quantitative Biology 2025-04-25 Ruijie Wang , Luca Rossetto , Susan Mérillat , Christina Röcke , Mike Martin , Abraham Bernstein

Robust and generalizable segmentation of brain tumors on multi-parametric magnetic resonance imaging (MRI) remains difficult because tumor types differ widely. The BraTS 2025 Lighthouse Challenge benchmarks segmentation methods on diverse…

The number of samples in structural brain MRI studies is often too small to properly train deep learning models. Generative models show promise in addressing this issue by effectively learning the data distribution and generating…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Wei Peng , Tian Xia , Fabio De Sousa Ribeiro , Tomas Bosschieter , Ehsan Adeli , Qingyu Zhao , Ben Glocker , Kilian M. Pohl