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Background: Multi-collimator proton minibeam radiation therapy (MC-pMBRT) has recently emerged as a versatile technique for dose shaping, enabling peak-valley dose patterns in organs-at-risk (OAR) while maintaining a uniform dose…

Medical Physics · Physics 2025-02-25 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

Brain tumor segmentation is a critical task in medical image analysis, aiding in the diagnosis and treatment planning of brain tumor patients. The importance of automated and accurate brain tumor segmentation cannot be overstated. It…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Muhammad Ansab Butt , Absaar Ul Jabbar

Recent work has shown potential in using Mixed Integer Programming (MIP) solvers to optimize certain aspects of neural networks (NNs). However the intriguing approach of training NNs with MIP solvers is under-explored.…

Machine Learning · Computer Science 2023-04-03 Tómas Thorbjarnarson , Neil Yorke-Smith

Breast cancer remains a critical global health challenge, necessitating early and accurate detection for effective treatment. This paper introduces a methodology that combines automated image augmentation selection (RandAugment) with search…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Leon Hamnett , Mary Adewunmi , Modinat Abayomi , Kayode Raheem , Fahad Ahmed

Precise delineation of meningiomas is crucial for effective radiotherapy (RT) planning, directly influencing treatment efficacy and preservation of adjacent healthy tissues. While automated deep learning approaches have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Junhyeok Lee , Han Jang , Kyu Sung Choi

Tumor segmentation in oncological PET is challenging, a major reason being the partial-volume effects that arise due to low system resolution and finite voxel size. The latter results in tissue-fraction effects, i.e. voxels contain a…

Introduction: The present study on the development and evaluation of an automated brain tumor segmentation technique based on deep learning using the 3D U-Net model. Objectives: The objective is to leverage state-of-the-art convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Suman Sourabh , Murugappan Valliappan , Narayana Darapaneni , Anwesh R P

In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…

Medical Physics · Physics 2015-06-16 Hamed Yarmand , David Craft

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Fueled by recent advances in machine learning, there has been tremendous progress in the field of semantic segmentation for the medical image computing community. However, developed algorithms are often optimized and validated by hand based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Oliver Rippel , Leon Weninger , Dorit Merhof

We consider a discrete optimization formulation for learning sparse classifiers, where the outcome depends upon a linear combination of a small subset of features. Recent work has shown that mixed integer programming (MIP) can be used to…

Machine Learning · Statistics 2021-06-08 Antoine Dedieu , Hussein Hazimeh , Rahul Mazumder

Deep neural network models used for medical image segmentation are large because they are trained with high-resolution three-dimensional (3D) images. Graphics processing units (GPUs) are widely used to accelerate the trainings. However, the…

Machine Learning · Computer Science 2018-12-20 Haruki Imai , Samuel Matzek , Tung D. Le , Yasushi Negishi , Kiyokuni Kawachiya

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

MRI tumor segmentation remains a critical challenge in medical imaging, where volumetric analysis faces unique computational demands due to the complexity of 3D data. The spatially sequential arrangement of adjacent MRI slices provides…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Jiacheng Lu , Hui Ding , Shiyu Zhang , Guoping Huo

The main treatment modality for oropharyngeal cancer (OPC) is radiotherapy, where accurate segmentation of the primary gross tumor volume (GTVp) is essential. However, accurate GTVp segmentation is challenging due to significant…

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Ken C. L. Wong , Tanveer Syeda-Mahmood , Mehdi Moradi

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

The 2024 Brain Tumor Segmentation Meningioma Radiotherapy (BraTS-MEN-RT) challenge aimed to advance automated segmentation algorithms using the largest known multi-institutional dataset of 750 radiotherapy planning brain MRIs with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Dominic LaBella , Valeriia Abramova , Mehdi Astaraki , Andre Ferreira , Zhifan Jiang , Mason C. Cleveland , Ramandeep Kang , Uma M. Lal-Trehan Estrada , Cansu Yalcin , Rachika E. Hamadache , Clara Lisazo , Adrià Casamitjana , Joaquim Salvi , Arnau Oliver , Xavier Lladó , Iuliana Toma-Dasu , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger , Daniel Capellán-Martín , Abhijeet Parida , Austin Tapp , Xinyang Liu , Maria J. Ledesma-Carbayo , Jay B. Patel , Thomas N. McNeal , Maya Viera , Owen McCall , Albert E. Kim , Elizabeth R. Gerstner , Christopher P. Bridge , Katherine Schumacher , Michael Mix , Kevin Leu , Shan McBurney-Lin , Pierre Nedelec , Javier Villanueva-Meyer , David R. Raleigh , Jonathan Shapey , Tom Vercauteren , Kazumi Chia , Marina Ivory , Theodore Barfoot , Omar Al-Salihi , Justin Leu , Lia M. Halasz , Yuri S. Velichko , Chunhao Wang , John P. Kirkpatrick , Scott R. Floyd , Zachary J. Reitman , Trey C. Mullikin , Eugene J. Vaios , Christina Huang , Ulas Bagci , Sean Sachdev , Jona A. Hattangadi-Gluth , Tyler M. Seibert , Nikdokht Farid , Connor Puett , Matthew W. Pease , Kevin Shiue , Syed Muhammad Anwar , Shahriar Faghani , Peter Taylor , Pranav Warman , Jake Albrecht , András Jakab , Mana Moassefi , Verena Chung , Rong Chai , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Nazanin Maleki , Rachit Saluja , Florian Kofler , Christopher G. Schwarz , Philipp Lohmann , Phillipp Vollmuth , Louis Gagnon , Maruf Adewole , Hongwei Bran Li , Anahita Fathi Kazerooni , Nourel Hoda Tahon , Udunna Anazodo , Ahmed W. Moawad , Bjoern Menze , Marius George Linguraru , Mariam Aboian , Benedikt Wiestler , Ujjwal Baid , Gian-Marco Conte , Andreas M. Rauschecker , Ayman Nada , Aly H. Abayazeed , Raymond Huang , Maria Correia de Verdier , Jeffrey D. Rudie , Spyridon Bakas , Evan Calabrese

Brain tumor segmentation is a critical task for tumor volumetric analyses and AI algorithms. However, it is a time-consuming process and requires neuroradiology expertise. While there has been extensive research focused on optimizing brain…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Partoo Vafaeikia , Matthias W. Wagner , Uri Tabori , Birgit B. Ertl-Wagner , Farzad Khalvati

Volumetric lesion segmentation via medical imaging is a powerful means to precisely assess multiple time-point lesion/tumor changes. Because manual 3D segmentation is prohibitively time consuming and requires radiological experience,…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Jinzheng Cai , Youbao Tang , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers