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Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic…

Purpose: To develop a fast and precise method for searching rectangular regions in brain tumor images. Methods: The authors propose a new method for searching rectangular tumor regions in brain MR images. The proposed method consisted of a…

Image and Video Processing · Electrical Eng. & Systems 2026-01-08 Hidenori Takeshima , Shuki Maruyama

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Segmenting multiple objects (e.g., organs) in medical images often requires an understanding of their topology, which simultaneously quantifies the shape of the objects and their positions relative to each other. This understanding is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Mehmet Bahadir Erden , Sinan Unver , Ilke Ali Gurses , Rustu Turkay , Cigdem Gunduz-Demir

Automated medical image segmentation plays an important role in many clinical applications, which however is a very challenging task, due to complex background texture, lack of clear boundary and significant shape and texture variation…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Qikui Zhu , Liang Li , Jiangnan Hao , Yunfei Zha , Yan Zhang , Yanxiang Cheng , Fei Liao , Pingxiang Li

This report presents a normalization block for automated tumor segmentation in CT/PET scans, developed for the autoPET III Challenge. The key innovation is the introduction of the SineNormal, which applies periodic sine transformations to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jintao Ren , Muheng Li , Stine Sofia Korreman

Tumor segmentation in PET-CT images is challenging due to the dual nature of the acquired information: low metabolic information in CT and low spatial resolution in PET. U-Net architecture is the most common and widely recognized approach…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Simone Bendazzoli , Mehdi Astaraki

Brain tumor segmentation is a critical task for patient's disease management. In order to automate and standardize this task, we trained multiple U-net like neural networks, mainly with deep supervision and stochastic weight averaging, on…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Theophraste Henry , Alexandre Carre , Marvin Lerousseau , Theo Estienne , Charlotte Robert , Nikos Paragios , Eric Deutsch

A major challenge in brain tumor treatment planning and quantitative evaluation is determination of the tumor extent. The noninvasive magnetic resonance imaging (MRI) technique has emerged as a front-line diagnostic tool for brain tumors…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Hao Dong , Guang Yang , Fangde Liu , Yuanhan Mo , Yike Guo

Medical Image Segmentation (MIS) plays a crucial role in medical therapy planning and robot navigation. Prototype learning methods in MIS focus on generating segmentation masks through pixel-to-prototype comparison. However, current…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Zhe Wang , Chang Yao

Automation of brain tumor segmentation in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Laura Mora Ballestar , Veronica Vilaplana

State-of-the-art brain tumor segmentation is based on deep learning models applied to multi-modal MRIs. Currently, these models are trained on images after a preprocessing stage that involves registration, interpolation, brain extraction…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Bruno Machado Pacheco , Guilherme de Souza e Cassia , Danilo Silva

Early diagnosis and accurate segmentation of brain tumors are imperative for successful treatment. Unfortunately, manual segmentation is time consuming, costly and despite extensive human expertise often inaccurate. Here, we present an…

Image and Video Processing · Electrical Eng. & Systems 2019-10-07 Markus Frey , Matthias Nau

Label-free vibrational microscopy provides chemically specific access to cellular structure, yet quantitative volumetric chemical dynamics in living cells remain largely inaccessible, particularly on subsecond timescales relevant to…

Automated segmentation of cancerous lesions in PET/CT scans is a crucial first step in quantitative image analysis. However, training deep learning models for segmentation with high accuracy is particularly challenging due to the variations…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Shadab Ahamed

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

Detection of tumors in metastatic colorectal cancer (mCRC) plays an essential role in the early diagnosis and treatment of liver cancer. Deep learning models backboned by fully convolutional neural networks (FCNNs) have become the dominant…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Ramtin Mojtahedi , Mohammad Hamghalam , Richard K. G. Do , Amber L. Simpson

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Carlos Nácher Collado

Automated segmentation tools often encounter accuracy and adaptability issues when applied to images of different pathology. The purpose of this study is to explore the feasibility of building a workflow to efficiently route images to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Peilong Wang , Timothy L. Kline , Andy D. Missert , Cole J. Cook , Matthew R. Callstrom , Alex Chan , Robert P. Hartman , Zachary S. Kelm , Panagiotis Korfiatis
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