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Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Large Language Models (LLMs) can be tasked with scoring texts according to pre-defined criteria and on a defined scale, but there is no recognised optimal prompting strategy for this. This article focuses on the task of LLMs scoring journal…

Digital Libraries · Computer Science 2025-12-02 Mike Thelwall

Large language models are increasingly used for vulnerability detection, yet their reliability under different prompt formulations remains uncharacterized. We present PromptAudit, a controlled evaluation framework that isolates prompt…

Machine Learning · Computer Science 2026-05-26 Steffen J. Camarato , Yahya Hmaiti , Mandana Ghadamian , David Mohaisen

LLM serving systems typically treat user prompts as monolithic inputs, optimizing inference through decoding tricks or inter-query batching. However, many real-world prompts contain latent semantic parallelism--decomposable structures where…

Machine Learning · Computer Science 2025-10-22 Steven Kolawole , Keshav Santhanam , Virginia Smith , Pratiksha Thaker

In prompt tuning, a prefix or suffix text is added to the prompt, and the embeddings (soft prompts) or token indices (hard prompts) of the prefix/suffix are optimized to gain more control over language models for specific tasks. This…

Computation and Language · Computer Science 2024-07-01 Shouchang Guo , Sonam Damani , Keng-hao Chang

Performing inference on large volumes of samples with large language models (LLMs) can be computationally and financially costly in industry and real-world use. We propose batch prompting, a simple yet effective prompting approach that…

Computation and Language · Computer Science 2023-10-25 Zhoujun Cheng , Jungo Kasai , Tao Yu

Uncovering latent values and opinions embedded in large language models (LLMs) can help identify biases and mitigate potential harm. Recently, this has been approached by prompting LLMs with survey questions and quantifying the stances in…

Computation and Language · Computer Science 2025-09-01 Dustin Wright , Arnav Arora , Nadav Borenstein , Srishti Yadav , Serge Belongie , Isabelle Augenstein

The latest generation of LLMs can be prompted to achieve impressive zero-shot or few-shot performance in many NLP tasks. However, since performance is highly sensitive to the choice of prompts, considerable effort has been devoted to…

Computation and Language · Computer Science 2023-11-06 Alina Leidinger , Robert van Rooij , Ekaterina Shutova

Large language models (LLMs) have achieved huge success in numerous natural language process (NLP) tasks. However, it faces the challenge of significant resource consumption during inference. In this paper, we aim to improve the inference…

Computation and Language · Computer Science 2024-02-05 Hanlin Zhu , Banghua Zhu , Jiantao Jiao

We present Prompt Cache, an approach for accelerating inference for large language models (LLM) by reusing attention states across different LLM prompts. Many input prompts have overlapping text segments, such as system messages, prompt…

Computation and Language · Computer Science 2024-04-26 In Gim , Guojun Chen , Seung-seob Lee , Nikhil Sarda , Anurag Khandelwal , Lin Zhong

Large language models (LLMs) enable system builders today to create competent NLP systems through prompting, where they only need to describe the task in natural language and provide a few examples. However, in other ways, LLMs are a step…

Computation and Language · Computer Science 2023-08-24 Vijay Viswanathan , Chenyang Zhao , Amanda Bertsch , Tongshuang Wu , Graham Neubig

Large Language Models (LLMs) have shown outstanding performance across a variety of tasks, partly due to advanced prompting techniques. However, these techniques often require lengthy prompts, which increase computational costs and can…

Computation and Language · Computer Science 2025-04-16 Jinwu Hu , Wei Zhang , Yufeng Wang , Yu Hu , Bin Xiao , Mingkui Tan , Qing Du

Synthetic data has become a cornerstone for scaling large language models, yet its multilingual use remains bottlenecked by translation-based prompts. This strategy inherits English-centric framing and style and neglects cultural…

Computation and Language · Computer Science 2025-10-23 David Mora , Viraat Aryabumi , Wei-Yin Ko , Sara Hooker , Julia Kreutzer , Marzieh Fadaee

In long context scenarios, large language models (LLMs) face three main challenges: higher computational cost, performance reduction, and position bias. Research indicates that LLM performance hinges on the density and position of key…

Computation and Language · Computer Science 2024-08-13 Huiqiang Jiang , Qianhui Wu , Xufang Luo , Dongsheng Li , Chin-Yew Lin , Yuqing Yang , Lili Qiu

Large language models (LLMs) are increasingly deployed in specialized production data processing pipelines across diverse domains -- such as finance, marketing, and e-commerce. However, when running them in production across many inputs,…

Computation and Language · Computer Science 2025-04-22 Reya Vir , Shreya Shankar , Harrison Chase , Will Fu-Hinthorn , Aditya Parameswaran

Large language model (LLM) performance depends heavily on prompt design, yet prompt construction is often described and applied inconsistently. Our purpose was to derive a reference framework for structuring LLM prompts. This paper presents…

Computation and Language · Computer Science 2026-04-17 David A. Cook

In-context learning has established itself as an important learning paradigm for Large Language Models (LLMs). In this paper, we demonstrate that LLMs can learn encoding keys in-context and perform analysis directly on encoded…

Computation and Language · Computer Science 2026-04-16 Andresa Rodrigues de Campos , David Lee , Imry Kissos , Piyush Paritosh

The large language models have achieved superior performance on various natural language tasks. One major drawback of such approaches is they are resource-intensive in fine-tuning new datasets. Soft-prompt tuning presents a…

Computation and Language · Computer Science 2023-10-30 Guoxin Chen , Yiming Qian , Bowen Wang , Liangzhi Li

In large scale recommendation systems like the LinkedIn Feed, the retrieval stage is critical for narrowing hundreds of millions of potential candidates to a manageable subset for ranking. LinkedIn's Feed serves suggested content from…

Large Language Models (LLMs) have shown remarkable capabilities in manipulating natural language across multiple applications, but their ability to handle simple reasoning tasks is often questioned. In this work, we aim to provide a…

Computation and Language · Computer Science 2025-05-05 Alessandro Raganato , Rafael Peñaloza , Marco Viviani , Gabriella Pasi