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There is a growing need to semantically process and integrate clinical data from different sources for Clinical Data Management and Clinical Decision Support in the healthcare IT industry. In the clinical practice domain, the semantic gap…

Databases · Computer Science 2012-10-25 Hong Sun , Kristof Depraetere , Jos De Roo , Boris De Vloed , Giovanni Mels , Dirk Colaert

Commonly adopted in the manufacturing and aerospace sectors, digital twin (DT) platforms are increasingly seen as a promising paradigm to control, monitor, and analyze software-based, "open", communication systems. Notably, DT platforms…

Signal Processing · Electrical Eng. & Systems 2023-08-30 Clement Ruah , Osvaldo Simeone , Bashir Al-Hashimi

Ontologies are widely used for achieving interoperable Digital Twins (DTws), yet competing DTw definitions compound interoperability issues. Semantically linking these differing twins is feasible through ontologies and Cognitive Digital…

Emerging Technologies · Computer Science 2024-04-17 James Michael Tooth , Nilufer Tuptuk , Jeremy Daniel McKendrick Watson

The current body of research on Parkinson's disease (PD) screening, monitoring, and management has evolved along two largely independent trajectories. The first research community focuses on multimodal sensing of PD-related biomarkers using…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Hassan Hizeh , Rim Chighri , Muhammad Mahboob Ur Rahman , Mohamed A. Bahloul , Ali Muqaibel , Tareq Y. Al-Naffouri

Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal…

In this paper, we introduce a decentralized digital twin (DDT) framework for dynamical systems and discuss the prospects of the DDT modeling paradigm in computational science and engineering applications. The DDT approach is built on a…

Machine Learning · Computer Science 2022-07-26 Omer San , Suraj Pawar , Adil Rasheed

The application of machine learning on healthcare data is often hindered by the lack of standardized and semantically explicit representation, leading to limited interoperability and reproducibility across datasets and experiments. The…

Machine Learning · Computer Science 2026-02-03 Alberto Marfoglia , Jong Ho Jhee , Adrien Coulet

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

In recent years, predictive maintenance (PMx) has gained prominence for its potential to enhance efficiency, automation, accuracy, and cost-effectiveness while reducing human involvement. Importantly, PMx has evolved in tandem with digital…

Artificial Intelligence · Computer Science 2024-10-23 Sizhe Ma , Katherine A. Flanigan , Mario Bergés

Virtual patients and digital patients/twins are two similar concepts gaining increasing attention in health care with goals to accelerate drug development and improve patients' survival, but with their own limitations. Although methods have…

Other Quantitative Biology · Quantitative Biology 2024-06-25 Hanwen Wang , Theinmozhi Arulraj , Alberto Ippolito , Aleksander S. Popel

Digital Twins (DTs) are becoming increasingly vital for future industrial applications, enhancing monitoring, control, and optimization of physical assets. This enhancement is made possible by integrating various Digital Models (DMs) within…

AI-based persona simulation -- often referred to as digital twin simulation -- is increasingly used for market research, recommender systems, and social sciences. Despite their flexibility, large language models (LLMs) often exhibit…

Machine Learning · Computer Science 2026-04-10 Grace Jiarui Fan , Chengpiao Huang , Tianyi Peng , Kaizheng Wang , Yuhang Wu

Beyond 5G networks provide solutions for next-generation communications, especially digital twins networks (DTNs) have gained increasing popularity for bridging physical space and digital space. However, current DTNs networking frameworks…

Networking and Internet Architecture · Computer Science 2023-12-19 Yang Hong , Jun Wu , Rosario Morello

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Digital twins are models of real-world systems that can simulate their dynamics in response to potential actions. In complex settings, the state and action variables, and available data and knowledge relevant to a system can constantly…

Computation and Language · Computer Science 2025-07-23 Harry Amad , Nicolás Astorga , Mihaela van der Schaar

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

Cyber attacks targeting Industrial Control Systems (ICS) have become increasingly sophisticated and hard to identify. Detecting such attacks requires integrating low-level behavioral cues with high-level semantic interpretation, a…

Cryptography and Security · Computer Science 2026-04-07 Konstantinos E. Kampourakis , Vasileios Gkioulos , Sokratis Katsikas

This paper investigates the transformative potential of digital twin (DT) technology for non-terrestrial networks (NTNs). NTNs, comprising airborne and space-borne elements, face unique challenges in network control, management, and…

Networking and Internet Architecture · Computer Science 2024-11-20 Hayder Al-Hraishawi , Madyan Alsenwi , Junaid ur Rehman , Eva Lagunas , Symeon Chatzinotas

The concept of a digital twin has exploded in popularity over the past decade, yet confusion around its plurality of definitions, its novelty as a new technology, and its practical applicability still exists, all despite numerous reviews,…

Machine Learning · Computer Science 2022-06-27 Brian Kunzer , Mario Berges , Artur Dubrawski

Recent developments in Artificial Intelligence (AI) and Machine Learning (ML) are creating new opportunities for Human-Autonomy Teaming (HAT) in tasks, missions, and continuous coordinated activities. A major challenge is enabling humans to…

Human-Computer Interaction · Computer Science 2025-04-07 Abdul Mannan Mohammed , Azhar Ali Mohammad , Jason A. Ortiz , Carsten Neumann , Grace Bochenek , Dirk Reiners , Carolina Cruz-Neira
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