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Diffusion probabilistic models have demonstrated significant potential in generating high-quality, realistic medical images, providing a promising solution to the persistent challenge of data scarcity in the medical field. Nevertheless,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Delin An , Chaoli Wang

The performance of medical image segmentation is increasingly defined by the efficiency of data utilization rather than merely the volume of raw data. Accurate segmentation, particularly for complex pathologies like meningiomas, demands…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Yunhao Xu , Fuquan Zong , Yexuan Xing , Chulong Zhang , Guang Yang , Shilong Yang , Xiaokun Liang , Juan Yu

In this paper, we present an effective data augmentation framework leveraging the Large Language Model (LLM) and Diffusion Model (DM) to tackle the challenges inherent in data-scarce scenarios. Recently, DMs have opened up the possibility…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Kyuheon Jung , Yongdeuk Seo , Seongwoo Cho , Jaeyoung Kim , Hyun-seok Min , Sungchul Choi

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Recent advances in computer vision have led to significant progress in the generation of realistic image data, with denoising diffusion probabilistic models proving to be a particularly effective method. In this study, we demonstrate that…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Dennis Eschweiler , Rüveyda Yilmaz , Matisse Baumann , Ina Laube , Rijo Roy , Abin Jose , Daniel Brückner , Johannes Stegmaier

Generating high-fidelity and biologically plausible synthetic single-cell RNA sequencing (scRNA-seq) data, especially with conditional control, is challenging due to its high dimensionality, sparsity, and complex biological variations.…

Machine Learning · Computer Science 2025-06-17 Lorenzo Bini , Stephane Marchand-Maillet

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Neural networks provide a powerful tool for applications from classification and regression to general purpose alternative computing. Photonics have the potential to provide enormous speed benefits over electronic and software networks,…

Signal Processing · Electrical Eng. & Systems 2018-10-18 Ethan Gordon

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Generative models capture the true distribution of data, yielding semantically rich representations. Denoising diffusion models (DDMs) exhibit superior generative capabilities, though efficient representation learning for them are lacking.…

Machine Learning · Computer Science 2025-05-12 Limai Jiang , Yunpeng Cai

Accurate segmentation of rectal lymph nodes is crucial for the staging and treatment planning of rectal cancer. However, the complexity of the surrounding anatomical structures and the scarcity of annotated data pose significant challenges.…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Weidong Guo , Hantao Zhang , Shouhong Wan , Bingbing Zou , Wanqin Wang , Peiquan Jin

Transforming in-situ transmission electron microscopy (TEM) imaging into a tool for spatially-resolved operando characterization of solid-state reactions requires automated, high-precision semantic segmentation of dynamically evolving…

Image and Video Processing · Electrical Eng. & Systems 2025-07-23 Yushuo Niu , Tianyu Li , Yuanyuan Zhu , Qian Yang

Recent advances in tuning-free personalized image generation based on diffusion models are impressive. However, to improve subject fidelity, existing methods either retrain the diffusion model or infuse it with dense visual embeddings, both…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Zhichao Wei , Qingkun Su , Long Qin , Weizhi Wang

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

We present multimodal conditioning modules (MCM) for enabling conditional image synthesis using pretrained diffusion models. Previous multimodal synthesis works rely on training networks from scratch or fine-tuning pretrained networks, both…

Computer Vision and Pattern Recognition · Computer Science 2023-05-22 Cusuh Ham , James Hays , Jingwan Lu , Krishna Kumar Singh , Zhifei Zhang , Tobias Hinz

Score-based diffusion models (SBDM) have recently emerged as state-of-the-art approaches for image generation. Existing SBDMs are typically formulated in a finite-dimensional setting, where images are considered as tensors of finite size.…

Machine Learning · Computer Science 2024-10-22 Paul Hagemann , Sophie Mildenberger , Lars Ruthotto , Gabriele Steidl , Nicole Tianjiao Yang

Advancements in text-to-image generative AI with large multimodal models are spreading into the field of image compression, creating high-quality representation of images at extremely low bit rates. This work introduces novel components to…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Cheng-Lin Wu , Hyomin Choi , Ivan V. Bajić