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Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Super Resolution (SR) plays a critical role in computer vision, particularly in medical imaging, where hardware and acquisition time constraints often result in low spatial and temporal resolution. While diffusion models have been applied…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Vishal Dubey

In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Multi-modal images play a crucial role in comprehensive evaluations in medical image analysis providing complementary information for identifying clinically important biomarkers. However, in clinical practice, acquiring multiple modalities…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

High-resolution (HR) MRI scans obtained from research-grade medical centers provide precise information about imaged tissues. However, routine clinical MRI scans are typically in low-resolution (LR) and vary greatly in contrast and spatial…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Jueqi Wang , Jacob Levman , Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , M. Jorge Cardoso , Razvan Marinescu

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Latent diffusion models (LDMs) have made significant advancements in the field of image generation in recent years. One major advantage of LDMs is their ability to operate in a compressed latent space, allowing for more efficient training…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Christina Zhang , Simran Motwani , Matthew Yu , Ji Hou , Felix Juefei-Xu , Sam Tsai , Peter Vajda , Zijian He , Jialiang Wang

Purpose: To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Yonatan Urman , Zachary Shah , Ashwin Kumar , Bruno P. Soares , Kawin Setsompop

Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Jiaxu Zheng , Meiman He , Xuhui Tang , Xiong Wang , Tuoyu Cao , Tianyi Zeng , Lichi Zhang , Chenyu You

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Jianqiang Lin , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Xiaoli Liu

Scaling by training on large datasets has been shown to enhance the quality and fidelity of image generation and manipulation with diffusion models; however, such large datasets are not always accessible in medical imaging due to cost and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Yousef Yeganeh , Azade Farshad , Ioannis Charisiadis , Marta Hasny , Martin Hartenberger , Björn Ommer , Nassir Navab , Ehsan Adeli

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Latent diffusion models (LDMs) power state-of-the-art high-resolution generative image models. LDMs learn the data distribution in the latent space of an autoencoder (AE) and produce images by mapping the generated latents into RGB image…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Tariq Berrada , Pietro Astolfi , Melissa Hall , Marton Havasi , Yohann Benchetrit , Adriana Romero-Soriano , Karteek Alahari , Michal Drozdzal , Jakob Verbeek

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

Latent Diffusion Models (LDMs) enable high-quality image synthesis while avoiding excessive compute demands by training a diffusion model in a compressed lower-dimensional latent space. Here, we apply the LDM paradigm to high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Andreas Blattmann , Robin Rombach , Huan Ling , Tim Dockhorn , Seung Wook Kim , Sanja Fidler , Karsten Kreis

This research presents a novel framework for the compression and decompression of medical images utilizing the Latent Diffusion Model (LDM). The LDM represents advancement over the denoising diffusion probabilistic model (DDPM) with a…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 InChan Hwang , MinJae Woo
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