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Related papers: Few-shot Molecular Property Prediction: A Survey

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Molecular property prediction (MPP) is a cornerstone of drug discovery and materials science, yet conventional deep learning approaches depend on large labeled datasets that are often unavailable. Few-shot Molecular property prediction…

Machine Learning · Computer Science 2025-10-27 Xiangyang Xu , Hongyang Gao

Molecular property prediction (MPP) is integral to drug discovery and material science, but often faces the challenge of data scarcity in real-world scenarios. Addressing this, few-shot molecular property prediction (FSMPP) has been…

Machine Learning · Computer Science 2024-11-05 Liang Wang , Qiang Liu , Shaozhen Liu , Xin Sun , Shu Wu , Liang Wang

Few-shot learning is a promising approach to molecular property prediction as supervised data is often very limited. However, many important molecular properties depend on complex molecular characteristics -- such as the various 3D…

Machine Learning · Computer Science 2023-10-10 Christopher Fifty , Joseph M. Paggi , Ehsan Amid , Jure Leskovec , Ron Dror

Molecular property prediction (MPP) is a fundamental and crucial task in drug discovery. However, prior methods are limited by the requirement for a large number of labeled molecules and their restricted ability to generalize for unseen and…

Quantitative Methods · Quantitative Biology 2024-10-21 Yuyan Liu , Sirui Ding , Sheng Zhou , Wenqi Fan , Qiaoyu Tan

The recent success of graph neural networks has significantly boosted molecular property prediction, advancing activities such as drug discovery. The existing deep neural network methods usually require large training dataset for each…

Machine Learning · Computer Science 2021-02-17 Zhichun Guo , Chuxu Zhang , Wenhao Yu , John Herr , Olaf Wiest , Meng Jiang , Nitesh V. Chawla

Few-shot molecular property prediction (FSMPP) is essential in drug discovery and materials design, where high-quality labeled data are often scarce and expensive to obtain. Despite the promising performance of existing methods, especially…

Computational Engineering, Finance, and Science · Computer Science 2026-05-14 Zeyu Wang , Xin Zheng , Yao Lu , Shanqing Yu , Qi Xuan , Shirui Pan

Molecular Property Prediction (MPP) plays a pivotal role across diverse domains, spanning drug discovery, material science, and environmental chemistry. Fueled by the exponential growth of chemical data and the evolution of artificial…

Machine Learning · Computer Science 2024-08-23 Tanya Liyaqat , Tanvir Ahmad , Chandni Saxena

Recently, few-shot molecular property prediction (FSMPP) has garnered increasing attention. Despite impressive breakthroughs achieved by existing methods, they often overlook the inherent many-to-many relationships between molecules and…

Quantitative Methods · Quantitative Biology 2024-05-27 Zeyu Wang , Tianyi Jiang , Yao Lu , Xiaoze Bao , Shanqing Yu , Bin Wei , Qi Xuan

Molecular property is usually observed with a limited number of samples, and researchers have considered property prediction as a few-shot problem. One important fact that has been ignored by prior works is that each molecule can be…

Machine Learning · Computer Science 2023-06-30 Xiang Zhuang , Qiang Zhang , Bin Wu , Keyan Ding , Yin Fang , Huajun Chen

In-context learning has become an important approach for few-shot learning in Large Language Models because of its ability to rapidly adapt to new tasks without fine-tuning model parameters. However, it is restricted to applications in…

Machine Learning · Computer Science 2023-10-16 Christopher Fifty , Jure Leskovec , Sebastian Thrun

Molecular property prediction plays a fundamental role in drug discovery to identify candidate molecules with target properties. However, molecular property prediction is essentially a few-shot problem which makes it hard to use regular…

Machine Learning · Computer Science 2021-11-12 Yaqing Wang , Abulikemu Abuduweili , Quanming Yao , Dejing Dou

Predicting the activities of compounds against protein-based or phenotypic assays using only a few known compounds and their activities is a common task in target-free drug discovery. Existing few-shot learning approaches are limited to…

Machine Learning · Computer Science 2023-11-29 Peter Eckmann , Jake Anderson , Michael K. Gilson , Rose Yu

Few-shot classification aims to recognize novel categories with only few labeled images in each class. Existing metric-based few-shot classification algorithms predict categories by comparing the feature embeddings of query images with…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Hung-Yu Tseng , Hsin-Ying Lee , Jia-Bin Huang , Ming-Hsuan Yang

In this paper, we look at cross-domain few-shot classification which presents the challenging task of learning new classes in previously unseen domains with few labelled examples. Existing methods, though somewhat effective, encounter…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Rashindrie Perera , Saman Halgamuge

Few-shot Learning aims to learn and distinguish new categories with a very limited number of available images, presenting a significant challenge in the realm of deep learning. Recent researchers have sought to leverage the additional…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Chunpeng Zhou , Haishuai Wang , Xilu Yuan , Zhi Yu , Jiajun Bu

Few-shot Learning (FSL), which endeavors to develop the generalization ability for recognizing novel classes using only a few images, faces significant challenges due to data scarcity. Recent CLIP-like methods based on contrastive…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Wei Zhuo , Runjie Luo , Wufeng Xue , Linlin Shen

Machine learning for molecular property prediction has focused largely on pure compounds, even though many practical applications depend on mixtures with intermolecular interactions. Recent work has expanded the availability of mixture…

Machine Learning · Computer Science 2026-05-29 Roel J. Leenhouts , Nathan K. Morgan , William Green , Jan G. Rittig , Florence H. Vermeire

Molecular Property Prediction (MPP) is vital for drug discovery, crop protection, and environmental science. Over the last decades, diverse computational techniques have been developed, from using simple physical and chemical properties and…

Machine Learning · Computer Science 2024-04-08 Afnan Sultan , Jochen Sieg , Miriam Mathea , Andrea Volkamer

Few-shot image classification learns to recognize new categories from limited labelled data. Metric learning based approaches have been widely investigated, where a query sample is classified by finding the nearest prototype from the…

Computer Vision and Pattern Recognition · Computer Science 2021-06-04 Zhizheng Zhang , Cuiling Lan , Wenjun Zeng , Zhibo Chen , Shih-Fu Chang

Few-shot learning aims to classify unseen classes with only a limited number of labeled data. Recent works have demonstrated that training models with a simple transfer learning strategy can achieve competitive results in few-shot…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Jingquan Wang , Jing Xu , Yu Pan , Zenglin Xu
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