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Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…
High-precision surface defect detection in manufacturing is essential for ensuring quality control. Laser triangulation profilometric sensors are key to this process, providing detailed and accurate surface measurements over a line. To…
The goal of this thesis is to provide a framework for the use of task-based metrics of image quality to aid in the design, implementation, and evaluation of CT image reconstruction algorithms and CT systems in general. We support the view…
The use of CT imaging is important for screening, diagnosis, therapy planning, and prognosis of lung cancers. Unfortunately, due to differences in imaging protocols and scanner models, CT images acquired by different means may show large…
Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…
Three-dimensional (3D) reconstruction of head Computed Tomography (CT) images elucidates the intricate spatial relationships of tissue structures, thereby assisting in accurate diagnosis. Nonetheless, securing an optimal head CT scan…
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…
This article is intended to supplement our 2015 paper in Medical Physics titled "Noise properties of CT images reconstructed by use of constrained total-variation, data-discrepancy minimization", in which ordered subsets methods were…
Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…
Deep learning-based low-dose computed tomography reconstruction methods already achieve high performance on standard image quality metrics like peak signal-to-noise ratio and structural similarity index measure. Yet, they frequently fail to…
X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…
In X-ray Computed Tomography (CT), projections from many angles are acquired and used for 3D reconstruction. To make CT suitable for in-line quality control, reducing the number of angles while maintaining reconstruction quality is…
We introduce a reinforcement learning (RL) based adaptive optimization algorithm for aerodynamic shape optimization focused on dimensionality reduction. The form in which RL is applied here is that of a surrogate-based, actor-critic policy…
Liver cancer is one of the most prevalent and lethal forms of cancer, making early detection crucial for effective treatment. This paper introduces a novel approach for automated liver tumor segmentation in computed tomography (CT) images…
Computed Tomography (CT) is an essential non-destructive three dimensional imaging modality used in medicine, security screening, and inspection of manufactured components. Typical CT data acquisition entails the collection of a thousand or…
Accelerated magnetic resonance imaging resorts to either Fourier-domain subsampling or better reconstruction algorithms to deal with fewer measurements while still generating medical images of high quality. Determining the optimal sampling…
Spectral Photon-Counting Computed Tomography (SPCCT) is a promising technology that has shown a number of advantages over conventional X-ray Computed Tomography (CT) in the form of material separation, artefact removal and enhanced image…
We design a new iterative algorithm, called REINFORCE-OPT, for solving a general type of optimization problems. This algorithm parameterizes the solution search rule and iteratively updates the parameter using a reinforcement learning (RL)…
Traditional X-ray computed tomography (CT) scanning strategies typically select projection angles uniformly and allocate dose equally. In practice, however, CT scans often need to be fast, radiation-efficient, and adaptive. Sparse-view…
The prognosis for patients with epithelial ovarian cancer remains dismal despite improvements in survival for other cancers. Treatment involves multiple lines of chemotherapy and becomes increasingly heterogeneous after first-line therapy.…