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Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

Diffusion models have emerged as a promising approach for text generation, with recent works falling into two main categories: discrete and continuous diffusion models. Discrete diffusion models apply token corruption independently using…

Computation and Language · Computer Science 2025-05-29 Bocheng Li , Zhujin Gao , Linli Xu

The design of novel molecules with desired properties is a key challenge in drug discovery and materials science. Traditional methods rely on trial-and-error, while recent deep learning approaches have accelerated molecular generation.…

Machine Learning · Computer Science 2025-03-10 Md Atik Ahamed , Qiang Ye , Qiang Cheng

Recently, diffusion transformers have gained wide attention with its excellent performance in text-to-image and text-to-vidoe models, emphasizing the need for transformers as backbone for diffusion models. Transformer-based models have…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Nithin Gopalakrishnan Nair , Jeya Maria Jose Valanarasu , Vishal M. Patel

Despite their success, unsupervised domain adaptation methods for semantic segmentation primarily focus on adaptation between image domains and do not utilize other abundant visual modalities like depth, infrared and event. This limitation…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Ruihao Xia , Yu Liang , Peng-Tao Jiang , Hao Zhang , Bo Li , Yang Tang , Pan Zhou

Recently, deep generative models have revealed itself as a promising way of performing de novo molecule design. However, previous research has focused mainly on generating SMILES strings instead of molecular graphs. Although current graph…

Quantitative Methods · Quantitative Biology 2018-04-24 Yibo Li , Liangren Zhang , Zhenming Liu

Graph property prediction tasks are important and numerous. While each task offers a small size of labeled examples, unlabeled graphs have been collected from various sources and at a large scale. A conventional approach is training a model…

Machine Learning · Computer Science 2023-10-13 Gang Liu , Eric Inae , Tong Zhao , Jiaxin Xu , Tengfei Luo , Meng Jiang

Data-driven deep learning models have enabled tremendous progress in change detection (CD) with the support of pixel-level annotations. However, collecting diverse data and manually annotating them is costly, laborious, and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Qi Zang , Jiayi Yang , Shuang Wang , Dong Zhao , Wenjun Yi , Zhun Zhong

Graph generative models are essential across diverse scientific domains by capturing complex distributions over relational data. Among them, graph diffusion models achieve superior performance but face inefficient sampling and limited…

Machine Learning · Computer Science 2025-06-17 Yiming Qin , Manuel Madeira , Dorina Thanou , Pascal Frossard

Diffusion Models (DMs) have emerged as powerful generative models with unprecedented image generation capability. These models are widely used for data augmentation and creative applications. However, DMs reflect the biases present in the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Rishubh Parihar , Abhijnya Bhat , Abhipsa Basu , Saswat Mallick , Jogendra Nath Kundu , R. Venkatesh Babu

Diffusion models have emerged as powerful tools for molecular generation, particularly in the context of 3D molecular structures. Inspired by non-equilibrium statistical physics, these models can generate 3D molecular structures with…

Chemical Physics · Physics 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

Diffusion models (DMs) have revolutionized generative learning. They utilize a diffusion process to encode data into a simple Gaussian distribution. However, encoding a complex, potentially multimodal data distribution into a single…

Machine Learning · Computer Science 2024-07-04 Yilun Xu , Gabriele Corso , Tommi Jaakkola , Arash Vahdat , Karsten Kreis

Diffusion models, as a type of generative model, have achieved impressive results in generating images and videos conditioned on textual conditions. However, the generation process of diffusion models involves denoising dozens of steps to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Hui Zhang , Zuxuan Wu , Zhen Xing , Jie Shao , Yu-Gang Jiang

Multi-label classification has broad applications and depends on powerful representations capable of capturing multi-label interactions. We introduce \textit{Diff-Feat}, a simple but powerful framework that extracts intermediate features…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tian Lan , Yiming Zheng , Jianxin Yin

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub

Understanding the neural basis of behavior is a fundamental goal in neuroscience. Current research in large-scale neuro-behavioral data analysis often relies on decoding models, which quantify behavioral information in neural data but lack…

Neurons and Cognition · Quantitative Biology 2024-11-27 Yule Wang , Chengrui Li , Weihan Li , Anqi Wu

Beyond high-fidelity image synthesis, diffusion models have recently exhibited promising results in dense visual perception tasks. However, most existing work treats diffusion models as a standalone component for perception tasks, employing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Shuhong Zheng , Zhipeng Bao , Ruoyu Zhao , Martial Hebert , Yu-Xiong Wang

This paper proposes a unified diffusion framework (dubbed UniDiffuser) to fit all distributions relevant to a set of multi-modal data in one model. Our key insight is -- learning diffusion models for marginal, conditional, and joint…

Machine Learning · Computer Science 2023-05-31 Fan Bao , Shen Nie , Kaiwen Xue , Chongxuan Li , Shi Pu , Yaole Wang , Gang Yue , Yue Cao , Hang Su , Jun Zhu

Real-world databases are predominantly relational, comprising multiple interlinked tables that contain complex structural and statistical dependencies. Learning generative models on relational data has shown great promise in generating…

Machine Learning · Computer Science 2025-06-03 Valter Hudovernik , Minkai Xu , Juntong Shi , Lovro Šubelj , Stefano Ermon , Erik Štrumbelj , Jure Leskovec

Diffusion models (DMs) have become the new trend of generative models and have demonstrated a powerful ability of conditional synthesis. Among those, text-to-image diffusion models pre-trained on large-scale image-text pairs are highly…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Wenliang Zhao , Yongming Rao , Zuyan Liu , Benlin Liu , Jie Zhou , Jiwen Lu
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