Related papers: Spike-frequency and h-current based adaptation are…
During slow-wave sleep, the brain is in a self-organized regime in which slow oscillations (SOs) between up- and down-states travel across the cortex. While an isolated piece of cortex can produce SOs, the brain-wide propagation of these…
Many types of neurons exhibit spike rate adaptation, mediated by intrinsic slow $\mathrm{K}^+$-currents, which effectively inhibit neuronal responses. How these adaptation currents change the relationship between in-vivo like fluctuating…
The human brain is a complex dynamical system which displays a wide range of macroscopic and mesoscopic patterns of neural activity, whose mechanistic origin remains poorly understood. Whole-brain modelling allows us to explore candidate…
Recurrently coupled networks of inhibitory neurons robustly generate oscillations in the gamma band. Nonetheless, the corresponding Wilson-Cowan type firing rate equation for such an inhibitory population does not generate such oscillations…
Author summary: Synchronization of neuronal spiking in the brain is related to cognitive functions, such as perception, attention, and memory. It is therefore important to determine which properties of neurons influence their collective…
Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…
Cortical slow oscillations are an emergent property of the cortical network, a hallmark of low complexity brain states like sleep, and represent a default activity pattern. Here, we present a methodological approach for quantifying the…
Spike-frequency adaptation (SFA) is a fundamental neuronal mechanism taking into account the fatigue due to spike emissions and the consequent reduction of the firing activity. We have studied the effect of this adaptation mechanism on the…
The relation between spontaneous and stimulated brain activity is a fundamental question in neuroscience, which has received wide attention in experimental studies. Recently, it has been suggested that the evoked response to external…
Slow waves (SWs) are spatio-temporal patterns of cortical activity that occur both during natural sleep and anesthesia and are preserved across species. Even though electrophysiological recordings have been largely used to characterize…
Population-wide oscillations are ubiquitously observed in mesoscopic signals of cortical activity. In these network states a global oscillatory cycle modulates the propensity of neurons to fire. Synchronous activation of neurons has been…
A universal mechanism of emergence of synchronized low frequency brain wave field activity is presented as a result of nonlinear coupling with flat frequency neuronal forcing. The mechanism utilizes a unique dispersion properties of…
Traveling waves of neural activity emerge in cortical networks both spontaneously and in response to stimuli. The spatiotemporal structure of waves can indicate the information they encode and the physiological processes that sustain them.…
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic…
Strong inhibitory input to neurons, which occurs in balanced states of neural networks, increases synaptic current fluctuations. This has led to the assumption that inhibition contributes to the high spike-firing irregularity observed in…
Human cognition emerges from coordinated spiking dynamics in distributed neural circuits, where information is encoded via both firing rates and precise spike timing determined by brain rhythms. Inspired by this notion, we propose a…
Biological neurons receive multiple noisy oscillatory signals, and their dynamical response to the superposition of these signals is of fundamental importance for information processing in the brain. Here we study the response of neural…
Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…
Spiking neural networks (SNN) distinguish themselves from artificial neural networks (ANN) because of their inherent temporal processing and spike-based computations, enabling a power-efficient implementation in neuromorphic hardware. In…
This work investigates the spatio-temporal evolution of coherentstructures in the wake of a high-speed train. SPOD is used to extract energy spectra and empirical modes for both symmetric and antisymmetric components of the fluctuating flow…