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A pivotal task for quantum computing is to speed up solving problems that are both classically intractable and practically valuable. Among these, combinatorial optimization problems have attracted tremendous attention due to their broad…

To witness quantum advantages in practical settings, substantial efforts are required not only at the hardware level but also on theoretical research to reduce the computational cost of a given protocol. Quantum computation has the…

Quantum Physics · Physics 2021-09-24 Daniel K. Park , Carsten Blank , Francesco Petruccione

This study develops a graph search algorithm to find the optimal discrimination path for the binary classification problem. The objective function is defined as the difference of variations between the true positive (TP) and false positive…

Machine Learning · Computer Science 2024-01-10 Qinwu Xu

Variational quantum algorithms are a class of techniques intended to be used on near-term quantum computers. The goal of these algorithms is to perform large quantum computations by breaking the problem down into a large number of shallow…

Quantum Physics · Physics 2023-03-24 Ryan Shaffer , Lucas Kocia , Mohan Sarovar

Optimization is finding the best solution, which mathematically amounts to locating the global minimum of some cost function. Optimization is traditionally automated with digital or quantum computers, each having their limitations and none…

Statistical Mechanics · Physics 2021-11-16 Natalia B. Janson , Christopher J. Marsden

Variational hybrid quantum-classical optimization represents one of the most promising avenue to show the advantage of nowadays noisy intermediate-scale quantum computers in solving hard problems, such as finding the minimum-energy state of…

Quantum Physics · Physics 2020-11-18 Laura Gentini , Alessandro Cuccoli , Stefano Pirandola , Paola Verrucchi , Leonardo Banchi

The Quantum Approximate Optimisation Algorithm is a $p$ layer, time-variable split operator method executed on a quantum processor and driven to convergence by classical outer loop optimisation. The classical co-processor varies individual…

Quantum Physics · Physics 2022-07-28 D. Rabinovich , R. Sengupta , E. Campos , V. Akshay , J. Biamonte

Quadratic unconstrained binary optimization (QUBO) has become the standard format for optimization using quantum computers, i.e., for both the quantum approximate optimization algorithm (QAOA) and quantum annealing (QA). We present a…

Quantum Physics · Physics 2022-04-26 Thomas Gabor , Marian Lingsch Rosenfeld , Sebastian Feld , Claudia Linnhoff-Popien

In recent years, variational quantum algorithms have garnered significant attention as a candidate approach for near-term quantum advantage using noisy intermediate-scale quantum (NISQ) devices. In this article we introduce kernel descent,…

Quantum Physics · Physics 2025-12-16 Lars Simon , Holger Eble , Manuel Radons

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

We propose a sequential minimal optimization method for quantum-classical hybrid algorithms, which converges faster, is robust against statistical error, and is hyperparameter-free. Specifically, the optimization problem of the…

Quantum Physics · Physics 2020-11-04 Ken M. Nakanishi , Keisuke Fujii , Synge Todo

An earlier work [18] proposes a method for solving the Lagrangian dual of a constrained binary quadratic programming problem via quantum adiabatic evolution using an outer approximation method. This should be an efficient prescription for…

Optimization and Control · Mathematics 2019-01-07 Sahar Karimi , Pooya Ronagh

Recently, there has been considerable interest in solving optimization problems by mapping these onto a binary representation, sparked mostly by the use of quantum annealing machines. Such binary representation is reminiscent of a discrete…

Quantum Physics · Physics 2021-07-30 Elisabetta Valiante , Maritza Hernandez , Amin Barzegar , Helmut G. Katzgraber

Many optimization techniques evaluate solutions consecutively, where the next candidate for evaluation is determined by the results of previous evaluations. For example, these include iterative methods, "black box" optimization algorithms,…

Artificial Intelligence · Computer Science 2018-09-03 Oleg V. Shylo , Hesam Shams

In this paper, we present an exact algorithm for optimizing two linear fractional over the efficient set of a multi-objective integer quadratic problem. This type of problems arises when two decision-makers, such as firms, each have a…

Optimization and Control · Mathematics 2024-02-05 Ali Bencheikh , Mustapha Moulai , Ilies Badaoui

This paper considers the task of performing binary search under noisy decisions, focusing on the application of target area localization. In the presence of noise, the classical partitioning approach of binary search is prone to error…

Information Theory · Computer Science 2025-05-01 Kaan Buyukkalayci , Merve Karakas , Xinlin Li , Christina Fragouli

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

Combinatorial optimization is considered a promising class of problems in which quantum computers can show significant advantages. However, problems of practical relevance typically have more variables than current or foreseeable quantum…

Quantum Physics · Physics 2025-12-23 Mathias Schmid , Naeimeh Mohseni , Michael J. Hartmann

We propose a scheme for solving mixed-integer programming problems in which the optimization problem is translated to a ground-state preparation problem on a set of bosonic quantum field modes (qumodes). We perform numerical demonstrations…

Quantum Physics · Physics 2023-11-13 Farhad Khosravi , Artur Scherer , Pooya Ronagh

The feedback-based algorithm for quantum optimization (FALQON) has recently been proposed to solve quadratic unconstrained binary optimization problems. This paper efficiently generalizes FALQON to tackle quadratic constrained binary…

Quantum Physics · Physics 2025-04-15 Salahuddin Abdul Rahman , Özkan Karabacak , Rafal Wisniewski