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Lung cancer is a devastating disease with the highest mortality rate among cancer types. Over 60% of non-small cell lung cancer (NSCLC) patients, which accounts for 87% of diagnoses, require radiation therapy. Rapid treatment initiation…

Image and Video Processing · Electrical Eng. & Systems 2024-08-02 Hamed Hooshangnejad , Xue Feng , Gaofeng Huang , Rui Zhang , Katelyn Kelly , Quan Chen , Kai Ding

Lung cancer is the primary cause of cancer death globally, with non-small cell lung cancer (NSCLC) emerging as its most prevalent subtype. Among NSCLC patients, approximately 32.3% have mutations in the epidermal growth factor receptor…

Pneumonia is a lung infection that causes 15% of childhood mortality, over 800,000 children under five every year, all over the world. This pathology is mainly caused by viruses or bacteria. X-rays imaging analysis is one of the most used…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Helena Liz , Manuel Sánchez-Montañés , Alfredo Tagarro , Sara Domínguez-Rodríguez , Ron Dagan , David Camacho

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

Applications · Statistics 2023-05-23 Roberta Coletti , Mónica L. Mendonça , Susana Vinga , Marta B. Lopes

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

Modeling and drawing inference on the joint associations between single nucleotide polymorphisms and a disease has sparked interest in genome-wide associations studies. In the motivating Boston Lung Cancer Survival Cohort (BLCSC) data, the…

Methodology · Statistics 2021-11-18 Lu Xia , Bin Nan , Yi Li

Excess hazard modeling is one of the main tools in population-based cancer survival research. Indeed, this setting allows for direct modeling of the survival due to cancer even in the absence of reliable information on the cause of death,…

Methodology · Statistics 2022-04-12 A. Eletti , G. Marra , M. Quaresma , R. Radice , F. J. Rubio

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Prostate cancer is the most common cancer in men worldwide and the second leading cause of cancer death in the United States. One of the prognostic features in prostate cancer is the Gleason grading of histopathology images. The Gleason…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Mohammad Mahdi Behzadi , Mohammad Madani , Hanzhang Wang , Jun Bai , Ankit Bhardwaj , Anna Tarakanova , Harold Yamase , Ga Hie Nam , Sheida Nabavi

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Lung cancer is a very deadly disease worldwide, and its early diagnosis is crucial for increasing patient survival rates. Computed tomography (CT) scans are widely used for lung cancer diagnosis as they can give detailed lung structures.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Md Rashidul Islam , Bakary Gibba , Altagi Abdallah Bakheit Abdelgadir

Breast cancer is one of the leading causes of mortality among women worldwide. Early detection and risk assessment play a crucial role in improving survival rates. Therefore, annual or biennial mammograms are often recommended for screening…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Batuhan K. Karaman , Katerina Dodelzon , Gozde B. Akar , Mert R. Sabuncu

MicroRNAs play an indispensable role in numerous biological processes ranging from organismic development to tumor progression.In oncology,these microRNAs constitute a fundamental regulation role in the pathology of cancer that provides the…

Quantitative Methods · Quantitative Biology 2022-01-17 Dietrich Kong , Ke Wang , Qiu-Ning Zhang , Zhi-Tong Bing

Lung cancer is the deadliest type of cancer for both men and women. Feature selection plays a vital role in cancer classification. This paper investigates the feature selection process in Computed Tomographic (CT) lung cancer images using…

Machine Learning · Computer Science 2012-12-24 G. Jothi , H. Hannah Inbarani

Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

Applications · Statistics 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Transformer-based models have achieved remarkable success in natural language and vision tasks, but their application to gene expression analysis remains limited due to data sparsity, high dimensionality, and missing values. We present…

Machine Learning · Computer Science 2025-04-15 Shuai Jiang , Saeed Hassanpour

In the medical field, accurate diagnosis of lung cancer is crucial for treatment. Traditional manual analysis methods have significant limitations in terms of accuracy and efficiency. To address this issue, this paper proposes a deep…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Ziyang Gao , Yong Tian , Shih-Chi Lin , Junghua Lin

Despite significant medical advancements, cancer remains the second leading cause of death, with over 600,000 deaths per year in the US. One emerging field, pathway analysis, is promising but still relies on manually derived wet lab data,…

Machine Learning · Computer Science 2025-09-17 Rishab Parthasarathy , Achintya Bhowmik