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Generating high-fidelity and biologically plausible synthetic single-cell RNA sequencing (scRNA-seq) data, especially with conditional control, is challenging due to its high dimensionality, sparsity, and complex biological variations.…

Machine Learning · Computer Science 2025-06-17 Lorenzo Bini , Stephane Marchand-Maillet

Early and accurate detection of Alzheimer's disease (AD) is crucial for enabling timely intervention and improving outcomes. However, developing reliable machine learning (ML) models for AD diagnosis is challenging due to limited labeled…

Machine Learning · Computer Science 2025-11-27 Abolfazl Moslemi , Hossein Peyvandi

The generation of images of realistic looking, readable handwritten text is a challenging task which is referred to as handwritten text generation (HTG). Given a string and examples from a writer, the goal is to synthesize an image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Kai Brandenbusch

Deep generative models have shown impressive results in generating realistic images of faces. GANs managed to generate high-quality, high-fidelity images when conditioned on semantic masks, but they still lack the ability to diversify their…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Nico Giambi , Giuseppe Lisanti

Large generative diffusion models have revolutionized text-to-image generation and offer immense potential for conditional generation tasks such as image enhancement, restoration, editing, and compositing. However, their widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Kangfu Mei , Mauricio Delbracio , Hossein Talebi , Zhengzhong Tu , Vishal M. Patel , Peyman Milanfar

Understanding the structure of real data is paramount in advancing modern deep-learning methodologies. Natural data such as images are believed to be composed of features organized in a hierarchical and combinatorial manner, which neural…

Machine Learning · Statistics 2024-12-25 Antonio Sclocchi , Alessandro Favero , Matthieu Wyart

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Graph generative modelling has become an essential task due to the wide range of applications in chemistry, biology, social networks, and knowledge representation. In this work, we propose a novel framework for generating graphs by adapting…

Machine Learning · Statistics 2026-02-04 Anthony Stephenson , Ian Gallagher , Christopher Nemeth

As acquiring MRIs is expensive, neuroscience studies struggle to attain a sufficient number of them for properly training deep learning models. This challenge could be reduced by MRI synthesis, for which Generative Adversarial Networks…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Wei Peng , Ehsan Adeli , Tomas Bosschieter , Sang Hyun Park , Qingyu Zhao , Kilian M. Pohl

Cortical surface analysis has gained increased prominence, given its potential implications for neurological and developmental disorders. Traditional vision diffusion models, while effective in generating natural images, present limitations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Zhenshan Xie , Simon Dahan , Logan Z. J. Williams , M. Jorge Cardoso , Emma C. Robinson

Discriminative classifiers have become a foundational tool in deep learning for medical imaging, excelling at learning separable features of complex data distributions. However, these models often need careful design, augmentation, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Gian Mario Favero , Parham Saremi , Emily Kaczmarek , Brennan Nichyporuk , Tal Arbel

Recently, 3D generation methods have shown their powerful ability to automate 3D model creation. However, most 3D generation methods only rely on an input image or a text prompt to generate a 3D model, which lacks the control of each…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Peng Li , Suizhi Ma , Jialiang Chen , Yuan Liu , Congyi Zhang , Wei Xue , Wenhan Luo , Alla Sheffer , Wenping Wang , Yike Guo

Diffusion models have exhibited impressive prowess in the text-to-image task. Recent methods add image-level structure controls, e.g., edge and depth maps, to manipulate the generation process together with text prompts to obtain desired…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Yibo Zhao , Liang Peng , Yang Yang , Zekai Luo , Hengjia Li , Yao Chen , Zheng Yang , Xiaofei He , Wei Zhao , qinglin lu , Boxi Wu , Wei Liu

Denoising Diffusion Probabilistic Models (DDPMs) have achieved remarkable success in various image generation tasks compared with Generative Adversarial Nets (GANs). Recent work on semantic image synthesis mainly follows the de facto…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Wengang Zhou , Weilun Wang , Jianmin Bao , Dongdong Chen , Dong Chen , Lu Yuan , Houqiang Li

Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion.…

In order to take advantage of AI solutions in endoscopy diagnostics, we must overcome the issue of limited annotations. These limitations are caused by the high privacy concerns in the medical field and the requirement of getting aid from…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Roman Macháček , Leila Mozaffari , Zahra Sepasdar , Sravanthi Parasa , Pål Halvorsen , Michael A. Riegler , Vajira Thambawita

Generating images from graph-structured inputs, such as scene graphs, is uniquely challenging due to the difficulty of aligning nodes and connections in graphs with objects and their relations in images. Most existing methods address this…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Ling Yang , Zhilin Huang , Yang Song , Shenda Hong , Guohao Li , Wentao Zhang , Bin Cui , Bernard Ghanem , Ming-Hsuan Yang

Image composition targets at synthesizing a realistic composite image from a pair of foreground and background images. Recently, generative composition methods are built on large pretrained diffusion models to generate composite images,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Bo Zhang , Yuxuan Duan , Jun Lan , Yan Hong , Huijia Zhu , Weiqiang Wang , Li Niu

Molecule generation is a very important practical problem, with uses in drug discovery and material design, and AI methods promise to provide useful solutions. However, existing methods for molecule generation focus either on 2D graph…

Machine Learning · Computer Science 2024-02-07 Chenqing Hua , Sitao Luan , Minkai Xu , Rex Ying , Jie Fu , Stefano Ermon , Doina Precup

In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong