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Since anatomic MRI is presently not able to directly discern neuronal loss in Parkinson's Disease (PD), studying the associated functional connectivity (FC) changes seems a promising approach toward developing non-invasive and…

Neurons and Cognition · Quantitative Biology 2018-02-07 Liviu Badea , Mihaela Onu , Tao Wu , Adina Roceanu , Ovidiu Bajenaru

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

We applied detrended fluctuation analysis, power spectral density, and eigenanalysis of detrended cross-correlations to investigate fMRI data representing a diurnal variation of working memory in four visual tasks: two verbal and two…

Missing modalities present a fundamental challenge in multimodal models, often causing catastrophic performance degradation. Our observations suggest that this fragility stems from an imbalanced learning process, where the model develops an…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Siqi Lu , Wanying Xu , Yongbin Zheng , Wenting Luan , Peng Sun , Jianhang Yao

Explaining individual differences in cognitive abilities requires both identifying brain parameters that vary across individuals and understanding how brain networks are recruited for specific tasks. Typically, task performance relies on…

Neurons and Cognition · Quantitative Biology 2026-05-05 Sida Chen , Siqi Yang , Zhao Chang , Taro Toyoizumi , Werner Sommer , Lianchun Yu , Qian-Yuan Tang , Changsong Zhou

Magnetic susceptibility imaging may provide valuable information about chemical composition and microstructural organization of tissue. However, its estimation from the MRI signal phase is particularly difficult as it is sensitive to…

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Automated segmentation of white matter hyperintensities (WMHs) is an essential step in neuroimaging analysis of Magnetic Resonance Imaging (MRI). Fluid Attenuated Inversion Recovery (FLAIR-weighted) is an MRI contrast that is particularly…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Martin Soria Røvang , Per Selnes , Bradley John MacIntosh , Inge Rasmus Groote , Lene Paalhaugen , Sudre Carole , Tormod Fladby , Atle Bjørnerud

In the vast expanse of our galaxy, white dwarfs (WDs) are natural sentinels, capturing the enigmatic dark matter (DM) particles that incessantly traverse their interiors. These celestial bodies provide a unique vantage point for probing…

High Energy Physics - Phenomenology · Physics 2024-06-06 Jia-Shu Niu

This study aimed to identify white matter (WM) deficits underlying the loss of consciousness in disorder of consciousness (DOC) patients using Diffusion Tensor Imaging (DTI) and to demonstrate the potential value of DTI parameters in…

Neurons and Cognition · Quantitative Biology 2016-11-28 Xuehai Wu , Jiaying Zhang , Zaixu Cui , Weijun Tang , Chunhong Shao , Jin Hu , Jianhong Zhu , Liangfu Zhou , Yao Zhao , Lu Lu , Gang Chen , Georg Northoff , Gaolang Gong , Ying Mao , Yong He

Granger Causality (GC) is widely used in neuroimaging to estimate directed statistical dependence among brain regions using time series of brain activity. An important issue is that functional MRI (fMRI) measures brain activity indirectly…

Neurons and Cognition · Quantitative Biology 2023-12-05 Leonardo Novelli , Lionel Barnett , Anil Seth , Adeel Razi

Factorization machine (FM) is a prevalent approach to modeling pairwise (second-order) feature interactions when dealing with high-dimensional sparse data. However, on the one hand, FM fails to capture higher-order feature interactions…

Machine Learning · Computer Science 2025-02-24 Shu Wu , Zekun Li , Yunyue Su , Zeyu Cui , Xiaoyu Zhang , Liang Wang

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

Neurons and Cognition · Quantitative Biology 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

We study the scale and redshift dependence of the power spectra for density perturbations and peculiar velocities, and the evolution of a coarse grained phase space density for (WDM) particles that decoupled during the radiation dominated…

Cosmology and Nongalactic Astrophysics · Physics 2011-05-12 Daniel Boyanovsky

Functional magnetic resonance imaging (fMRI) aims to locate activated regions in human brains when specific tasks are performed. The conventional tool for analyzing fMRI data applies some variant of the linear model, which is restrictive in…

Statistics Theory · Mathematics 2008-08-08 Chunming Zhang , Tao Yu

We consider the challenges in extracting stimulus-related neural dynamics from other intrinsic processes and noise in naturalistic functional magnetic resonance imaging (fMRI). Most studies rely on inter-subject correlations (ISC) of…

Neurons and Cognition · Quantitative Biology 2021-02-23 Chee-Ming Ting , Jeremy I. Skipper , Steven L. Small , Hernando Ombao

This paper reviews and extends some recent results on the multivariate fractional Brownian motion (mfBm) and its increment process. A characterization of the mfBm through its covariance function is obtained. Similarly, the correlation and…

We introduce a novel geometric framework for separating the phase and the amplitude variability in functional data of the type frequently studied in growth curve analysis. This framework uses the Fisher-Rao Riemannian metric to derive a…

Statistics Theory · Mathematics 2015-03-19 Anuj Srivastava , Wei Wu , Sebastian Kurtek , Eric Klassen , J. S. Marron
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