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We introduce MedCondDiff, a diffusion-based framework for multi-organ medical image segmentation that is efficient and anatomically grounded. The model conditions the denoising process on semantic priors extracted by a Pyramid Vision…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Ruirui Huang , Jiacheng Li

While Masked Diffusion Language Models (MDLMs) relying on token masking and unmasking have shown promise in language modeling, their computational efficiency and generation flexibility remain constrained by the masking paradigm. In this…

Computation and Language · Computer Science 2026-03-26 Fangyu Ding , Ding Ding , Sijin Chen , Kaibo Wang , Peng Xu , Zijin Feng , Haoli Bai , Kai Han , Youliang Yan , Binhang Yuan , Jiacheng Sun

Masked diffusion models (MDMs) have recently emerged as a novel framework for language modeling. MDMs generate sentences by iteratively denoising masked sequences, filling in [MASK] tokens step by step. Although MDMs support any-order…

Machine Learning · Computer Science 2026-02-27 Chunsan Hong , Seonho An , Min-Soo Kim , Jong Chul Ye

Diffusion language models intrinsically fail to capture correlations between decoded tokens, which leads to a harsh trade-off between sampling quality and throughput. To solve this issue, we propose DiLaDiff, a variant of masked diffusion…

Machine Learning · Computer Science 2026-05-25 Jean-Marie Lemercier , Tomas Geffner , Karsten Kreis , Morteza Mardani , Arash Vahdat , Ante Jukić

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Combining discrete and continuous data is an important capability for generative models. We present Discrete Flow Models (DFMs), a new flow-based model of discrete data that provides the missing link in enabling flow-based generative models…

Machine Learning · Statistics 2024-06-07 Andrew Campbell , Jason Yim , Regina Barzilay , Tom Rainforth , Tommi Jaakkola

Cross-modality data translation has attracted great interest in image computing. Deep generative models (\textit{e.g.}, GANs) show performance improvement in tackling those problems. Nevertheless, as a fundamental challenge in image…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Zihao Wang , Yingyu Yang , Maxime Sermesant , Hervé Delingette , Ona Wu

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Diffusion models (DMs) have demonstrated exceptional generative capabilities across various domains, including image, video, and so on. A key factor contributing to their effectiveness is the high quantity and quality of data used during…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Qianlong Xiang , Miao Zhang , Yuzhang Shang , Jianlong Wu , Yan Yan , Liqiang Nie

Multi-modal foundation models are typically trained on millions of pairs of natural images and text captions, frequently obtained through web-crawling approaches. Although such models depict excellent generative capabilities, they do not…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Pierre Chambon , Christian Bluethgen , Curtis P. Langlotz , Akshay Chaudhari

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Recently, diffusion models have demonstrated impressive capabilities in text-guided and image-conditioned image generation. However, existing diffusion models cannot simultaneously generate an image and a panoptic segmentation of objects…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Yinghan Long , Kaushik Roy

Diffusion language models (DLMs) are an attractive alternative to autoregressive models because they promise sublinear-time, parallel generation, yet practical gains remain elusive as high-quality samples still demand hundreds of refinement…

Machine Learning · Computer Science 2026-05-04 Hasan Amin , Yuan Gao , Yaser Souri , Subhojit Som , Ming Yin , Rajiv Khanna , Xia Song

Masked discrete diffusion models (MDMs) are a promising new approach to generative modelling, offering the ability for parallel token generation and therefore greater efficiency than autoregressive counterparts. However, achieving an…

Machine Learning · Computer Science 2026-03-02 David Fox , Sam Bowyer , Song Liu , Laurence Aitchison , Raul Santos-Rodriguez , Mengyue Yang

Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Kangbo Ma

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

This study introduces an efficient and effective method, MeDM, that utilizes pre-trained image Diffusion Models for video-to-video translation with consistent temporal flow. The proposed framework can render videos from scene position…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Ernie Chu , Tzuhsuan Huang , Shuo-Yen Lin , Jun-Cheng Chen

Predictive models trained on imbalanced data tend to produce biased results. This problem is exacerbated when there is not just one output label, but a set of them. This is the case for multilabel learning (MLL) algorithms used to classify…

Machine Learning · Computer Science 2025-01-22 Francisco Charte , Miguel Ángel Dávila , María Dolores Pérez-Godoy , María José del Jesus

Part of the success of diffusion models stems from their ability to perform iterative refinement, i.e., repeatedly correcting outputs during generation. However, modern masked discrete diffusion lacks this capability: when a token is…

Machine Learning · Computer Science 2026-02-10 Guanghan Wang , Yair Schiff , Subham Sekhar Sahoo , Volodymyr Kuleshov

Masked Diffusion Models (MDMs) offer a promising alternative to autoregressive language models by enabling parallel token generation and bidirectional context modeling. However, their inference speed is significantly limited by the…

Machine Learning · Computer Science 2026-04-08 Satyam Goyal , Kushal Patel , Tanush Mittal , Arjun Laxman