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Machine learning potentials (MLPs) have advanced rapidly and show great promise to transform molecular dynamics (MD) simulations. However, most existing software tools are tied to specific MLP architectures, lack integration with standard…

Computational Physics · Physics 2025-06-05 Paul Fuchs , Weilong Chen , Stephan Thaler , Julija Zavadlav

Mixed-precision training has emerged as an indispensable tool for enhancing the efficiency of neural network training in recent years. Concurrently, JAX has grown in popularity as a versatile machine learning toolbox. However, it currently…

Machine Learning · Computer Science 2025-10-28 Alexander Gräfe , Sebastian Trimpe

This paper introduces a novel software visualisation and animation method, manifested in a prototype software tool - AnimArch. The introduced method is based on model fusion of static and dynamic models. The static model is represented by…

Software Engineering · Computer Science 2025-01-15 Lukas Radosky , Ivan Polasek

We present JaxPP, a system for efficiently scaling the training of large deep learning models with flexible pipeline parallelism. We introduce a seamless programming model that allows implementing user-defined pipeline schedules for…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-20 Anxhelo Xhebraj , Sean Lee , Hanfeng Chen , Vinod Grover

In this thesis, we develop multiscale models for particle simulations in population dynamics. These models are characterised by prescribing particle motion on two spatial scales: microscopic and macroscopic. At the microscopic level, each…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Omar Richardson

Neural simulation-based inference (SBI) describes an emerging family of methods for Bayesian inference with intractable likelihood functions that use neural networks as surrogate models. Here we introduce sbijax, a Python package that…

Machine Learning · Computer Science 2026-03-23 Simon Dirmeier , Antonietta Mira , Carlo Albert

Combustion kinetic modeling is an integral part of combustion simulation, and extensive studies have been devoted to developing both high fidelity and computationally affordable models. Despite these efforts, modeling combustion kinetics is…

A new molecular simulation toolkit composed of some lately developed force fields and specified models is presented to study the self-assembly, phase transition, and other properties of polymeric systems at mesoscopic scale by utilizing the…

Computational Physics · Physics 2013-10-10 You-Liang Zhu , Hong Liu , Zhan-Wei Li , Hu-Jun Qian , Giuseppe Milano , Zhong-Yuan Lu

In this paper, a new progressive mesh algorithm is introduced in order to perform fast physical simulations by the use of a lattice Boltzmann method (LBM) on a single-node multi-GPU architecture. This algorithm is able to mesh automatically…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-10-14 Julien Duchateau , François Rousselle , Nicolas Maquignon , Gilles Roussel , Christophe Renaud

We present the IAMReX, an adaptive and parallel solver for particle-resolved simulations on the multi-level grid. The fluid equations are solved using a finite-volume scheme on the block-structured semi-staggered grids with both subcycling…

Fluid Dynamics · Physics 2024-08-27 Xuzhu Li , Chun Li , Xiaokai Li , Wenzhuo Li , Mingze Tang , Yadong Zeng , Zhengping Zhu

Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

We present GridFF, an efficient method for simulating molecules on rigid substrates, derived from techniques used in protein-ligand docking in biochemistry. By projecting molecule-substrate interactions onto precomputed spatial grids with…

Chemical Physics · Physics 2025-08-22 Indranil Mal , Milan Kočí , Paolo Nicolini , Prokop Hapala

A multi-platform validation and analysis framework for public Monte Carlo simulation for high-energy particle collisions is discussed. The front-end of this framework uses the Python programming language, while the back-end is written in…

Computational Physics · Physics 2017-10-25 S. V. Chekanov , I. Pogrebnyak , D. Wilbern

We developed a multiscale approach (MultiSCAAL) that integrates the potential of mean force (PMF) obtained from all-atomistic molecular dynamics simulations with a knowledge-based energy function for coarse-grained molecular simulations in…

Biological Physics · Physics 2010-05-10 Antonios Samiotakis , Dirar Homouz , Margaret S. Cheung

The acceleration of material property calculations while maintaining ab initio accuracy (1 meV/atom) is one of the major challenges in computational physics. In this paper, we introduce a Python package enhancing the computation of (finite…

The fast multipole method (FMM) has received growing attention in the beam physics simulation. In this study, we formulate an interpolation-based FMM for the computation of the relativistic space-charge field. Different to the…

Computational Physics · Physics 2023-07-19 Yi-Kai Kan , Franz X. Kärtner , Sabine Le Borne , Jens-Peter M. Zemke

Machine-learned interatomic potentials can offer near first-principles accuracy but are computationally expensive, limiting their application to large-scale molecular dynamics simulations. Inspired by quantum mechanics/molecular mechanics…

Materials Science · Physics 2025-11-21 Fraser Birks , Matthew Nutter , Thomas D Swinburne , James R Kermode

In this relation I present a technique of construction and fast evaluation of a family of cubic polynomials for analytic smoothing and graphical rendering of particles trajectories for flows in a generic geometry. The principal result of…

Numerical Analysis · Mathematics 2025-10-20 Gianluca Argentini

The conductor-like polarization model (C-PCM) with switching/Gaussian smooth discretization is a widely used implicit solvation model in chemical simulations. However, its application in quantum mechanical calculations of large-scale…

Chemical Physics · Physics 2015-07-03 Fang Liu , Nathan Luehr , Heather J. Kulik , Todd J. Martínez

GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest…

Computational Engineering, Finance, and Science · Computer Science 2015-06-03 Páll Szilárd , Mark James Abraham , Carsten Kutzner , Berk Hess , Erik Lindahl