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Modern randomization methods in clinical trials are invariably adaptive, meaning that the assignment of the next subject to a treatment group uses the accumulated information in the trial. Some of the recent adaptive randomization methods…

Methodology · Statistics 2024-02-12 Alan R. Vazquez , Weng Kee Wong

Statistical practices such as building regression models or running hypothesis tests rely on following rigorous procedures of steps and verifying assumptions on data to produce valid results. However, common statistical tools do not verify…

Human-Computer Interaction · Computer Science 2024-10-02 Yuqi Zhang , Adam Perer , Will Epperson

Statistics experiences a storm around the perceived misuse and possible abuse of its methods in the context of the so-called reproducibility crisis. The methods and styles of quantification practiced in mathematical modelling rarely make it…

Methodology · Statistics 2019-08-20 Andrea Saltelli

Context: Research software is essential for developing advanced tools and models to solve complex research problems and drive innovation across domains. Therefore, it is essential to ensure its correctness. Software testing plays a vital…

Software Engineering · Computer Science 2025-01-30 Nasir U. Eisty , Upulee Kanewala , Jeffrey C. Carver

Rapid advances in computation, combined with latest advances in computer graphics simulations have facilitated the development of vision systems and training them in virtual environments. One major stumbling block is in certification of the…

Computer Vision and Pattern Recognition · Computer Science 2015-12-07 V S R Veeravasarapu , Rudra Narayan Hota , Constantin Rothkopf , Ramesh Visvanathan

The Theory-Software Translation Workshop, held in New Orleans in February 2019, explored in depth the process of both instantiating theory in software - for example, implementing a mathematical model in code as part of a simulation - and…

Recently, it has been recognized that phase transitions play an important role in the probabilistic analysis of combinatorial optimization problems. However, there are in fact many other relations that lead to close ties between computer…

Statistical Mechanics · Physics 2007-05-23 O. C. Martin , R. Monasson , R. Zecchina

Computer simulations that demonstrate the valueof novel approaches are crucial to developing more flexibleand robust power systems operations with high penetrations ofrenewable energy at multiple geographic and temporal scales.However,…

Systems and Control · Electrical Eng. & Systems 2020-09-01 Jose Daniel Lara , Jonathan T. Lee , Duncan Callaway , Bri-Mathias Hodge

Nested simulation is a natural approach to tackle nested estimation problems in operations research and financial engineering. The outer-level simulation generates outer scenarios and the inner-level simulations are run in each outer…

Risk Management · Quantitative Finance 2022-03-31 Kun Zhang , Ben Mingbin Feng , Guangwu Liu , Shiyu Wang

The development of applications for obtaining interpretable results in a simple and summarized manner in multi-state models is a research field with great potential, namely in terms of using open source tools that can be easily implemented…

Computation · Statistics 2022-02-21 Gustavo Soutinho , Luís Meira-Machado

The Statistical Toolkit is an open source system specialized in the statistical comparison of distributions. It addresses requirements common to different experimental domains, such as simulation validation (e.g. comparison of experimental…

Computational Physics · Physics 2015-06-11 M Batic , A. M. Paganoni , A. Pfeiffer , M. G. Pia , A. Ribon

Studying the reliability of complex systems using machine learning techniques involves facing a series of technical and practical challenges, ranging from the intrinsic nature of the system and data to the difficulties in modeling and…

Machine Learning · Computer Science 2024-10-08 Maria Luz Gamiz , Fernando Navas-Gomez , Rafael Nozal-Cañadas , Rocio Raya-Miranda

Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not…

Quantitative Methods · Quantitative Biology 2010-01-20 Tina Toni , Michael P. H. Stumpf

Games can be a powerful tool for learning about statistical methodology. Effective game design involves a fine balance between caricature and realism, to simultaneously illustrate salient concepts in a controlled setting and serve as a…

Other Statistics · Statistics 2018-05-15 Robert B. Gramacy

Simulation is used extensively in autonomous systems, particularly in robotic manipulation. By far, the most common approach is to train a controller in simulation, and then use it as an initial starting point for the real system. We…

Machine Learning · Statistics 2021-10-06 Shirli Di Castro Shashua , Dotan Di Castro , Shie Mannor

The past decade has seen an increasing body of literature devoted to the estimation of causal effects in network-dependent data. However, the validity of many classical statistical methods in such data is often questioned. There is an…

Computation · Statistics 2017-05-31 Oleg Sofrygin , Romain Neugebauer , Mark J. van der Laan

Using Reinforcement Learning (RL) in simulation to construct policies useful in real life is challenging. This is often attributed to the sequential decision making aspect: inaccuracies in simulation accumulate over multiple steps, hence…

Machine Learning · Computer Science 2017-06-09 Rika Antonova , Silvia Cruciani

Increasingly demanding performance requirements for dynamical systems motivates the adoption of nonlinear and adaptive control techniques. One challenge is the nonlinearity of the resulting closed-loop system complicates verification that…

Systems and Control · Computer Science 2017-10-03 John F. Quindlen , Ufuk Topcu , Girish Chowdhary , Jonathan P. How

Computational models are quantitative representations of systems. By analyzing and comparing the outputs of such models, it is possible to gain a better understanding of the system itself. Though as the complexity of model outputs…

Machine Learning · Computer Science 2022-12-13 Colin G. Cess , Stacey D. Finley

Complex system simulation has been playing an irreplaceable role in understanding, predicting, and controlling diverse complex systems. In the past few decades, the multi-scale simulation technique has drawn increasing attention for its…

Systems and Control · Electrical Eng. & Systems 2024-07-25 Huandong Wang , Huan Yan , Can Rong , Yuan Yuan , Fenyu Jiang , Zhenyu Han , Hongjie Sui , Depeng Jin , Yong Li
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