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The requirement for accelerated and quantitatively accurate screening of nuclear magnetic resonance spectra across the small molecules chemical compound space is two-fold: (1) a robust `local' machine learning (ML) strategy capturing the…

Chemical Physics · Physics 2020-12-04 Amit Gupta , Sabyasachi Chakraborty , Raghunathan Ramakrishnan

Nuclear Magnetic Resonance (NMR) chemical shifts are powerful probes of local atomic and electronic structure that can be used to resolve the structures of powdered or amorphous molecular solids. Chemical shift driven structure elucidation…

Exact calculation of electronic properties of molecules is a fundamental step for intelligent and rational compounds and materials design. The intrinsically graph-like and non-vectorial nature of molecular data generates a unique and…

Chemical Physics · Physics 2019-10-29 Alain Tchagang , Julio Valdés

Structure determination by chemical-shift-driven NMR crystallography relies on comparing chemical shieldings measured in solid-state NMR experiments with simulations. However, computational cost limits the accuracy of shielding predictions,…

Theoretical predictions of NMR chemical shifts from first-principles can greatly facilitate experimental interpretation and structure identification. However, accurate prediction of chemical shifts using the best coupled cluster methods can…

Magnet errors in storage rings significantly degrade beam performance, impacting the brightness and stability of the light source. Therefore, beam-based correction is crucial for the safe operation of machines and the stability of radiated…

Accelerator Physics · Physics 2025-12-18 Jianhao Xu

Molecule representation learning is crucial for understanding and predicting molecular properties. However, conventional atom-centric models, which treat chemical bonds merely as pairwise interactions, often overlook complex bond-level…

Machine Learning · Computer Science 2026-03-03 Yunqing Liu , Yi Zhou , Wenqi Fan

Large machine learning models with improved predictions have become widely available in the chemical sciences. Unfortunately, these models do not protect the privacy necessary within commercial settings, prohibiting the use of potentially…

Cryptography and Security · Computer Science 2022-12-23 Jan Weinreich , Guido Falk von Rudorff , O. Anatole von Lilienfeld

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

Machine learning (ML) provides access to fast and accurate quantum chemistry (QC) calculations for various properties of interest such as excitation energies. It is often the case that high accuracy in prediction using an ML model, demands…

Chemical Physics · Physics 2024-03-13 Vivin Vinod , Ulrich Kleinekathöfer , Peter Zaspel

Recovery rate prediction plays a pivotal role in bond investment strategies by enhancing risk assessment, optimizing portfolio allocation, improving pricing accuracy, and supporting effective credit risk management. However, accurate…

Computational Finance · Quantitative Finance 2026-01-27 Ying Chen , Paul Griffin , Paolo Recchia , Lei Zhou , Hongrui Zhang

We introduce a robust, interpretable machine learning (ML) framework that combines numerical regression for high-accuracy predictions with symbolic regression to uncover the underlying physics. This hybrid approach effciently derives…

Nuclear Theory · Physics 2025-12-09 B. Maheshwari , P. Van Isacker

Nuclear magnetic resonance (NMR) spectroscopy provides an experimental readout of local chemical environments, but its use in molecular representation learning has been constrained by heterogeneous data and incomplete atom-level…

Chemical Physics · Physics 2026-05-12 Jiebin Fang , Zidi Yan , Churu Mao , Yongjun Jiang , Xinyi Tang , Lei Miao , Dan Lu , Yun Huang , Wanjing Ding , Zhongjun Ma

Recent studies illustrate how machine learning (ML) can be used to bypass a core challenge of molecular modeling: the tradeoff between accuracy and computational cost. Here, we assess multiple ML approaches for predicting the atomization…

Computational Physics · Physics 2022-02-15 Logan Ward , Ben Blaiszik , Ian Foster , Rajeev S. Assary , Badri Narayanan , Larry Curtiss

We investigate the impact of choosing regressors and molecular representations for the construction of fast machine learning (ML) models of thirteen electronic ground-state properties of organic molecules. The performance of each…

The predictive accuracy of Machine Learning (ML) models of molecular properties depends on the choice of the molecular representation. Based on the postulates of quantum mechanics, we introduce a hierarchy of representations which meet…

Chemical Physics · Physics 2016-11-23 Bing Huang , O. Anatole von Lilienfeld

Nuclear magnetic resonance (NMR) is a powerful spectroscopic technique that is sensitive to the local atomic structure of matter. Computational predictions of NMR parameters can help to interpret experimental data and validate structural…

Materials Science · Physics 2025-08-19 Chiheb Ben Mahmoud , Louise A. M. Rosset , Jonathan R. Yates , Volker L. Deringer

The success of any machine learning system depends critically on effective representations of data. In many cases, it is desirable that a representation scheme uncovers the parts-based, additive nature of the data. Of current representation…

Machine Learning · Computer Science 2017-08-21 Tu Dinh Nguyen , Truyen Tran , Dinh Phung , Svetha Venkatesh

We demonstrate identification of position, material, orientation and shape of objects imaged by an $^{85}$Rb atomic magnetometer performing electromagnetic induction imaging supported by machine learning. Machine learning maximizes the…

Atomic Physics · Physics 2018-01-24 Cameron Deans , Lewis D. Griffin , Luca Marmugi , Ferruccio Renzoni

Instant machine learning predictions of molecular properties are desirable for materials design, but the predictive power of the methodology is mainly tested on well-known benchmark datasets. Here, we investigate the performance of machine…

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