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Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Yunxiang Li , Bowen Jing , Zihan Li , Jing Wang , You Zhang

Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

Precision medicine, such as patient-adaptive treatments assisted by medical image analysis, poses new challenges for segmentation algorithms in adapting to new patients, due to the large variability across different patients and the limited…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Chenhui Zhao , Liyue Shen

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

The Segment Anything Model 2 (SAM2) has recently demonstrated exceptional performance in zero-shot prompt segmentation for natural images and videos. However, when the propagation mechanism of SAM2 is applied to medical images, it often…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Yunhao Bai , Boxiang Yun , Zeli Chen , Qinji Yu , Yingda Xia , Yan Wang

Background: We evaluate SAM 2 for surgical scene understanding by examining its semantic segmentation capabilities for organs/tissues both in zero-shot scenarios and after fine-tuning. Methods: We utilized five public datasets to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Devanish N. Kamtam , Joseph B. Shrager , Satya Deepya Malla , Xiaohan Wang , Nicole Lin , Juan J. Cardona , Serena Yeung-Levy , Clarence Hu

The Segment Anything Model 2 (SAM2) has demonstrated remarkable promptable visual segmentation capabilities in video data, showing potential for extension to medical image segmentation (MIS) tasks involving 3D volumes and temporally…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Meng Lan , Lefei Zhang , Xiaomeng Li

The reliance on large labeled datasets presents a significant challenge in medical image segmentation. Few-shot learning offers a potential solution, but existing methods often still require substantial training data. This paper proposes a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Haiyue Zu , Jun Ge , Heting Xiao , Jile Xie , Zhangzhe Zhou , Yifan Meng , Jiayi Ni , Junjie Niu , Linlin Zhang , Li Ni , Huilin Yang

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Lev Ayzenberg , Raja Giryes , Hayit Greenspan

The Segment Anything Model (SAM) has demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) claims to outperform SAM on images and extends the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Sourya Sengupta , Satrajit Chakrabarty , Ravi Soni

Leveraging pre-trained models with tailored prompts for in-context learning has proven highly effective in NLP tasks. Building on this success, recent studies have applied a similar approach to the Segment Anything Model (SAM) within a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hangyul Yoon , Doohyuk Jang , Jungeun Kim , Eunho Yang

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Medical image segmentation has greatly aided medical diagnosis, with U-Net based architectures and nnU-Net providing state-of-the-art performance. There have been numerous general promptable models and medical variations introduced in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Connor Ludwig , Khashayar Namdar , Farzad Khalvati

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

This paper presents a large publicly available multi-center lumbar spine magnetic resonance imaging (MRI) dataset with reference segmentations of vertebrae, intervertebral discs (IVDs), and spinal canal. The dataset includes 447 sagittal T1…

The Segment Anything Model (SAM) family has become a widely adopted vision foundation model, but its ability to control segmentation granularity remains limited. Users often need to refine results manually - by adding more prompts or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Junwei Yu , Trevor Darrell , XuDong Wang

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar
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