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Modern Augmented reality applications require performing multiple tasks on each input frame simultaneously. Multi-task learning (MTL) represents an effective approach where multiple tasks share an encoder to extract representative features…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Marina Neseem , Ahmed Agiza , Sherief Reda

Spatial stochastic molecular simulations in biology are limited by the intense computation required to track molecules in space either in a discrete time or discrete space framework, meaning that the serial limit has already been reached in…

Quantitative Methods · Quantitative Biology 2016-08-24 I. Hepburn , W. Chen , E. De Schutter

Molecular editing and optimization are multi-step problems that require iteratively improving properties while keeping molecules chemically valid and structurally similar. We frame both tasks as sequential, tool-guided decisions and…

Artificial Intelligence · Computer Science 2025-12-25 Zhuo Yang , Yeyun Chen , Jiaqing Xie , Ben Gao , Shuaike Shen , Wanhao Liu , Liujia Yang , Beilun Wang , Tianfan Fu , Yuqiang Li

The prediction of absorption, distribution, metabolism, excretion, and toxicity (ADMET) of small molecules from their molecular structure is a central problem in medicinal chemistry with great practical importance in drug discovery.…

Deep learning is now widely used in drug discovery, providing significant acceleration and cost reduction. As the most fundamental building block, molecular representation is essential for predicting molecular properties to enable various…

Machine Learning · Computer Science 2024-04-22 Haoqiang Guo , Sendong Zhao , Haochun Wang , Yanrui Du , Bing Qin

We study the tensor-optimized antisymmetrized molecular dynamics (TOAMD) as a successive variational method in many-body systems with strong interaction for nuclei. In TOAMD, the correlation functions for the tensor force and the…

Nuclear Theory · Physics 2017-05-09 Takayuki Myo , Hiroshi Toki , Kiyomi Ikeda , Hisashi Horiuchi , Tadahiro Suhara

The limited availability of annotations in small molecule datasets presents a challenge to machine learning models. To address this, one common strategy is to collaborate with additional auxiliary datasets. However, having more data does…

Biomolecules · Quantitative Biology 2023-11-10 Tinglin Huang , Ziniu Hu , Rex Ying

We develop a learning-based algorithm for the distributed formation control of networked multi-agent systems governed by unknown, nonlinear dynamics. Most existing algorithms either assume certain parametric forms for the unknown dynamic…

Systems and Control · Electrical Eng. & Systems 2022-07-19 Christos K. Verginis , Zhe Xu , Ufuk Topcu

Density Functional Theory (DFT) has been a cornerstone in computational science, providing powerful insights into structure-property relationships for molecules and materials through first-principles quantum-mechanical (QM) calculations.…

Chemical Physics · Physics 2024-08-13 Yicheng Chen , Wenjie Yan , Zhanfeng Wang , Jianming Wu , Xin Xu

Machine learning (ML) has emerged as a pervasive tool in science, engineering, and beyond. Its success has also led to several synergies with molecular dynamics (MD) simulations, which we use to identify and characterize the major…

Biomolecules · Quantitative Biology 2022-05-09 Christopher Kolloff , Simon Olsson

We propose AnyTOD, an end-to-end, zero-shot task-oriented dialog (TOD) system capable of handling unseen tasks without task-specific training. We view TOD as a program executed by a language model (LM), where program logic and ontology is…

Computation and Language · Computer Science 2023-02-14 Jeffrey Zhao , Yuan Cao , Raghav Gupta , Harrison Lee , Abhinav Rastogi , Mingqiu Wang , Hagen Soltau , Izhak Shafran , Yonghui Wu

Neural network potentials (NNPs) enable large-scale molecular dynamics (MD) simulations of systems containing >10,000 atoms with the accuracy comparable to ab initio methods and play a crucial role in material studies. Although NNPs are…

We demonstrate a machine learning based approach which can learn the time-dependent electronic excitation dynamics of small molecules subjected to ion irradiation. Ensembles of recurrent neural networks are trained on data generated by…

Chemical Physics · Physics 2024-09-24 Ethan P. Shapera , Cheng-Wei Lee

Representation learning of the task-oriented attention while tracking instrument holds vast potential in image-guided robotic surgery. Incorporating cognitive ability to automate the camera control enables the surgeon to concentrate more on…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Mobarakol Islam , Vibashan VS , Chwee Ming Lim , Hongliang Ren

Machine learning (ML) models hold the promise of transforming atomic simulations by delivering quantum chemical accuracy at a fraction of the computational cost. Realization of this potential would enable high-throughout, high-accuracy…

Metal-organic frameworks (MOFs) offer a vast design space, and as such, computational simulations play a critical role in predicting their structural and physicochemical properties. However, MOF simulations remain difficult to access…

Artificial Intelligence · Computer Science 2026-04-01 Jaewoong Lee , Taeun Bae , Jihan Kim

While the Self-Attention mechanism in the Transformer model has proven to be effective in many domains, we observe that it is less effective in more diverse settings (e.g. multimodality) due to the varying granularity of each token and the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Wayner Barrios , SouYoung Jin

Multi-task learning (MTL) can advance assistive driving by exploring inter-task correlations through shared representations. However, existing methods face two critical limitations: single-modality constraints limiting comprehensive scene…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Wenzhuo Liu , Yicheng Qiao , Zhen Wang , Qiannan Guo , Zilong Chen , Meihua Zhou , Xinran Li , Letian Wang , Zhiwei Li , Huaping Liu , Wenshuo Wang

Simultaneously optimizing multiple, frequently conflicting, molecular properties is a key bottleneck in the development of novel therapeutics. Although a promising approach, the efficacy of multi-task learning is often compromised by…

Machine Learning · Computer Science 2025-10-01 Mason Minot , Gisbert Schneider

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru