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Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

Neurons and Cognition · Quantitative Biology 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

Applications · Statistics 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

The study of hierarchy in networks of the human brain has been of significant interest among the researchers as numerous studies have pointed out towards a functional hierarchical organization of the human brain. This paper provides a novel…

Neurons and Cognition · Quantitative Biology 2021-03-02 Dushyant Sahoo , Theodore D. Satterthwaite , Christos Davatzikos

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Functional magnetic resonance imaging (fMRI) data provides information concerning activity in the brain and in particular the interactions between brain regions. Resting state fMRI data is widely used for inferring connectivities in the…

Applications · Statistics 2019-03-04 Christina Stoehr , John A D Aston , Claudia Kirch

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Emerging evidence shows that the modular organization of the human brain allows for better and efficient cognitive performance. Many of these cognitive functions are very fast and occur in subsecond time scale such as the visual object…

Neurons and Cognition · Quantitative Biology 2018-08-01 J. Rizkallah , P. Benquet , A. Kabbara , O. Dufor , F. Wendling , M. Hassan

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Recent studies on analyzing dynamic brain connectivity rely on sliding-window analysis or time-varying coefficient models which are unable to capture both smooth and abrupt changes simultaneously. Emerging evidence suggests state-related…

Applications · Statistics 2019-07-04 Chee-Ming Ting , Hernando Ombao , S. Balqis Samdin , Sh-Hussain Salleh

Dynamic functional connectivity (dFC) is ubiquitously observed in the brain, but why functional networks should remain dynamic even at rest is unclear. We asked whether temporal reconfiguration becomes advantageous when keeping a functional…

Biological Physics · Physics 2026-04-14 Simachew Abebe Mengiste , Demian Battaglia

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

We investigate whether and how we can improve the cost efficiency of neuroimaging studies with well-tailored fMRI tasks. The comparative study is conducted using a novel network science-driven Bayesian connectome-based predictive method,…

Applications · Statistics 2024-11-05 Xinzhi Zhang , Leslie A Hulvershorn , Todd Constable , Yize Zhao , Selena Wang

The human brain is a complex, dynamic network, which is commonly studied using functional magnetic resonance imaging (fMRI) and modeled as network of Regions of interest (ROIs) for understanding various brain functions. Recent studies…

Quantitative Methods · Quantitative Biology 2024-06-26 Yifan Yang , Yutong Mao , Xufu Liu , Xiao Liu

Predicting cognition from neuroimaging data in healthy individuals offers insights into the neural mechanisms underlying cognitive abilities, with potential applications in precision medicine and early detection of neurological and…

Machine Learning · Computer Science 2025-07-29 Jagruti Patel , Mikkel Schöttner , Thomas A. W. Bolton , Patric Hagmann

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

Neurons and Cognition · Quantitative Biology 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

Functional magnetic resonance imaging (fMRI) is widely used in clinical applications to highlight brain areas involved in specific cognitive processes. Brain impairments, such as tumors, suppress the fMRI activation of the anatomical areas…

Neurons and Cognition · Quantitative Biology 2019-06-20 Qiongge Li , Gino Del Ferraro , Luca Pasquini , Kyung K. Peck , Hernan A. Makse , Andrei I. Holodny

One approach, for understanding human brain functioning, is to analyze the changes in the brain while performing cognitive tasks. Towards this, Functional Magnetic Resonance (fMR) images of subjects performing well-defined tasks are widely…

Computer Vision and Pattern Recognition · Computer Science 2016-04-20 Hariharan Ramasangu , Neelam Sinha
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