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Accurate and timely cancer diagnosis from histopathological slides is vital for effective clinical decision-making. This paper introduces DepViT-CAD, a deployable AI system for multi-class cancer diagnosis in histopathology. At its core is…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Ashkan Shakarami , Lorenzo Nicole , Rocco Cappellesso , Angelo Paolo Dei Tos , Stefano Ghidoni

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

Image and Video Processing · Electrical Eng. & Systems 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Traditionally, pathological analysis and diagnosis are performed by manually eyeballing glass slide specimens under a microscope by an expert. The whole slide image is the digital specimen produced from the glass slide. Whole slide image…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Galib Muhammad Shahriar Himel

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Diffusion-weighted MRI is nowadays performed routinely due to its prognostic ability, yet the quality of the scans are often unsatisfactory which can subsequently hamper the clinical utility. To overcome the limitations, here we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Hyungjin Chung , Jaehyun Kim , Jeong Hee Yoon , Jeong Min Lee , Jong Chul Ye

The integration of Artificial Intelligence (AI) in medical diagnostics is often hindered by model opacity, where high-accuracy systems function as "black boxes" without transparent reasoning. This limitation is critical in clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Pascal Passigan , Vayd Ramkumar

Incomplete multi-modal medical image segmentation faces critical challenges from modality imbalance, including imbalanced modality missing rates and heterogeneous modality contributions. Due to their reliance on idealized assumptions of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Yudong Zhang

Melanoma segmentation in Whole Slide Images (WSIs) is useful for prognosis and the measurement of crucial prognostic factors such as Breslow depth and primary invasive tumor size. In this paper, we present a novel approach that uses the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Qingyuan Liu , Avideh Zakhor

Goal: Squamous cell carcinoma of cervix is one of the most prevalent cancer worldwide in females. Traditionally, the most indispensable diagnosis of cervix squamous carcinoma is histopathological assessment which is achieved under…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Ye Tian , Li Yang , Wei Wang , Jing Zhang , Qing Tang , Mili Ji , Yang Yu , Yu Li , Hong Yang , Airong Qian

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming, labor-intensive, and destructive to tissue. Standard…

Image and Video Processing · Electrical Eng. & Systems 2022-10-31 Yijie Zhang , Luzhe Huang , Tairan Liu , Keyi Cheng , Kevin de Haan , Yuzhu Li , Bijie Bai , Aydogan Ozcan

The difficulty of processing gigapixel whole slide images (WSIs) in clinical microscopy has been a long-standing barrier to implementing computer aided diagnostic systems. Since modern computing resources are unable to perform computations…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Sam Maksoud , Kun Zhao , Peter Hobson , Anthony Jennings , Brian Lovell

Hyperspectral imaging is one of the most promising techniques for intraoperative tissue characterisation. Snapshot mosaic cameras, which can capture hyperspectral data in a single exposure, have the potential to make a real-time…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Peichao Li , Michael Ebner , Philip Noonan , Conor Horgan , Anisha Bahl , Sebastien Ourselin , Jonathan Shapey , Tom Vercauteren

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

The emergence of digital pathology has opened new horizons for histopathology and cytology. Artificial-intelligence algorithms are able to operate on digitized slides to assist pathologists with diagnostic tasks. Whereas machine learning…

The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed and privacy-respecting images. The model supports zero-shot…

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Existing multi-focus image fusion (MFIF) methods often fail to preserve the uncertain transition region and detect small focus areas within large defocused regions accurately. To address this issue, this study proposes a new…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Xilai Li , Xiaosong Li , Haishu Tan , Jinyang Li

T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) are essential components for cervical cancer diagnosis. However, combining these channels for training deep learning models are challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Reza Kalantar , Sebastian Curcean , Jessica M Winfield , Gigin Lin , Christina Messiou , Matthew D Blackledge , Dow-Mu Koh

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu