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Related papers: Bridging Clinical Narratives and ACR Appropriatene…

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Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…

Quantitative Methods · Quantitative Biology 2025-10-08 Anni Tziakouri , Filippo Menolascina

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

Retrieval-Augmented Generation (RAG) is a powerful technique for enriching Large Language Models (LLMs) with external knowledge, allowing for factually grounded responses, a critical requirement in high-stakes domains such as healthcare.…

Computation and Language · Computer Science 2025-10-07 Eduardo Martínez Rivera , Filippo Menolascina

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

Computation and Language · Computer Science 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

Identifying the appropriate regulatory standard applicability remains a critical yet understudied challenge in medical device compliance, frequently necessitating expert interpretation of fragmented and heterogeneous documentation across…

Artificial Intelligence · Computer Science 2025-06-24 Yu Han , Aaron Ceross , Jeroen H. M. Bergmann

Retrieval-augmented generation (RAG) systems offer a promising approach to reduce hallucinations and improve answer accuracy in large language models (LLMs), a requirement for reliable, financial analysis where answers must be grounded in…

Machine Learning · Computer Science 2026-05-26 Magnus Samuelsen , Wilmer Nyström , Somnath Mazumdar , Mansoor Hussain , Mikkel Strange

Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

Advancements in generative Artificial Intelligence (AI) hold great promise for automating radiology workflows, yet challenges in interpretability and reliability hinder clinical adoption. This paper presents an automated radiology report…

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao

Retrieval-Augmented Generation (RAG) systems for biomedical literature are typically evaluated using ranking metrics like Mean Reciprocal Rank (MRR), which measure how well the system identifies the single most relevant chunk. We argue that…

Artificial Intelligence · Computer Science 2026-03-25 Pouria Mortezaagha , Arya Rahgozar

Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plans. Methods and Materials: We curated a multi-protocol…

Diagnostic imaging studies are an increasingly important component of the workup and management of acutely presenting patients. However, ordering appropriate imaging studies according to evidence-based medical guidelines is a challenging…

Machine Learning · Computer Science 2025-08-06 Michael S. Yao , Allison Chae , Charles E. Kahn , Walter R. Witschey , James C. Gee , Hersh Sagreiya , Osbert Bastani

Multidisciplinary team (MDT) consultations are the gold standard for cancer care decision-making, yet current practice lacks structured mechanisms for quantifying consensus and ensuring decision traceability. We introduce a Multi-Agent…

Multiagent Systems · Computer Science 2025-12-17 Xudong Han , Xianglun Gao , Xiaoyi Qu , Zhenyu Yu

Legal professionals need to write analyses that rely on citations to relevant precedents, i.e., previous case decisions. Intelligent systems assisting legal professionals in writing such documents provide great benefits but are challenging…

Computation and Language · Computer Science 2024-06-28 Abe Bohan Hou , Orion Weller , Guanghui Qin , Eugene Yang , Dawn Lawrie , Nils Holzenberger , Andrew Blair-Stanek , Benjamin Van Durme

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

Computation and Language · Computer Science 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

Accurate healthcare prediction is critical for improving patient outcomes and reducing operational costs. Bolstered by growing reasoning capabilities, large language models (LLMs) offer a promising path to enhance healthcare predictions by…

Artificial Intelligence · Computer Science 2025-11-18 Chuang Zhao , Hui Tang , Hongke Zhao , Xiaofang Zhou , Xiaomeng Li

Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and…

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

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