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Accurate intraoperative diagnosis is essential for providing safe and effective care during brain tumor surgery. Our standard-of-care diagnostic methods are time, resource, and labor intensive, which restricts access to optimal surgical…

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Efficient and effective assessment of acute and chronic wounds can help wound care teams in clinical practice to greatly improve wound diagnosis, optimize treatment plans, ease the workload and achieve health related quality of life to the…

Computers and Society · Computer Science 2021-10-13 D. M. Anisuzzaman , Chuanbo Wang , Behrouz Rostami , Sandeep Gopalakrishnan , Jeffrey Niezgoda , Zeyun Yu

To test the hypothesis that accuracy, discrimination, and precision in predicting postoperative complications improve when using both preoperative and intraoperative data input features versus preoperative data alone. Models that predict…

Purpose - To characterise and assess the quality of published research evaluating artificial intelligence (AI) methods for ovarian cancer diagnosis or prognosis using histopathology data. Methods - A search of PubMed, Scopus, Web of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-19 Jack Breen , Katie Allen , Kieran Zucker , Pratik Adusumilli , Andy Scarsbrook , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Digital pathology plays a crucial role in the development of artificial intelligence in the medical field. The digital pathology platform can make the pathological resources digital and networked, and realize the permanent storage of visual…

Human-Computer Interaction · Computer Science 2021-11-11 Jialun Wu , Anyu Mao , Xinrui Bao , Haichuan Zhang , Zeyu Gao , Chunbao Wang , Tieliang Gong , Chen Li

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

Artificial Intelligence (AI) brings advancements to support pathologists in navigating high-resolution tumor images to search for pathology patterns of interest. However, existing AI-assisted tools have not realized this promised potential…

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Tissue detection is a crucial first step in most digital pathology applications. Details of the segmentation algorithm are rarely reported, and there is a lack of studies investigating the downstream effects of a poor segmentation…

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

Clinical machine learning faces a critical dilemma in high-stakes medical applications: algorithms achieving optimal diagnostic performance typically sacrifice the interpretability essential for physician decision-making, while…

Machine Learning · Computer Science 2025-09-23 Xiuqi Ge , Zhibo Yao , Yaosong Du

Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

Purpose: Non-invasive grading of prostate cancer (PCa) from micro-ultrasound (micro-US) could expedite triage and guide biopsies toward the most aggressive regions, yet current models struggle to infer tissue micro-structure at coarse…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Emma Willis , Tarek Elghareb , Paul F. R. Wilson , Minh Nguyen Nhat To , Mohammad Mahdi Abootorabi , Amoon Jamzad , Brian Wodlinger , Parvin Mousavi , Purang Abolmaesumi

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu