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We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

In this paper, we propose stochastic structure-preserving schemes to compute the effective diffusivity for particles moving in random flows. We first introduce the motion of particles using the Lagrangian formulation, which is modeled by…

Numerical Analysis · Mathematics 2020-08-24 Junlong Lyu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

The widely used susceptible-infected-recovered (S-I-R) epidemic model assumes a uniform, well-mixed population, and incorporation of spatial heterogeneities remains a major challenge. Understanding failures of the mixing assumption is…

Soft Condensed Matter · Physics 2024-04-23 P. Forgacs , A. Libal , C. Reichhardt , N. Hengartner , C. J. O. Reichhardt

We present a simple model for the spread of an infection that incorporates spatial variability in population density. Starting from first principle considerations, we explore how a novel PDE with state-dependent diffusion can be obtained.…

Populations and Evolution · Quantitative Biology 2021-10-28 A. Vaziry , T. Kolokolnikov , P. G. Kevrekidis

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

Analysis of PDEs · Mathematics 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

This paper proposes an adaptive sparse polynomial chaos expansion(PCE)-based method to quantify the impacts of uncertainties on critical clearing time (CCT) that is an important index in transient stability analysis. The proposed method can…

Systems and Control · Electrical Eng. & Systems 2022-06-10 Jingyu Liu , Xiaoting Wang , Xiaozhe Wang

We consider a chemo-repulsion model with quadratic production in a bounded domain. Firstly, we obtain global in time weak solutions, and give a regularity criterion (which is satisfied for $1D$ and $2D$ domains) to deduce uniqueness and…

Numerical Analysis · Mathematics 2020-03-06 F. Guillén-González , M. A. Rodríguez-Bellido , D. A. Rueda-Gómez

Spatial reaction-diffusion models have been employed to describe many emergent phenomena in biological systems. The modelling technique most commonly adopted in the literature implements systems of partial differential equations (PDEs),…

Quantitative Methods · Quantitative Biology 2015-10-05 Christian A. Yates , Mark B. Flegg

Simulation of stochastic spatially-extended systems is a challenging problem. The fundamental quantities in these models are individual entities such as molecules, cells, or animals, which move and react in a random manner. In big systems,…

Quantitative Methods · Quantitative Biology 2024-09-24 Tomás Alarcón , Natalia Briñas-Pascual , Juan Calvo , Pilar Guerrero , Daria Stepanova

Continuous-time Markov process models of contagions are widely studied, not least because of their utility in predicting the evolution of real-world contagions and in formulating control measures. It is often the case, however, that…

Physics and Society · Physics 2016-11-23 Peter G. Fennell , Sergey Melnik , James P. Gleeson

The present work was inspired by the recent developments in laboratory experiments made on chip, where culturing of multiple cell species was possible. The model is based on coupled reaction-diffusion-transport equations with chemotaxis,…

Numerical Analysis · Mathematics 2020-07-22 E. C. Braun , G. Bretti , R. Natalini

Predicting the evolution of diseases is challenging, especially when the data availability is scarce and incomplete. The most popular tools for modelling and predicting infectious disease epidemics are compartmental models. They stratify…

Machine Learning · Computer Science 2023-10-10 Esha Saha , Lam Si Tung Ho , Giang Tran

Estimation of division and death rates of lymphocytes in different conditions is vital for quantitative understanding of the immune system. Deuterium, in the form of deuterated glucose or heavy water, can be used to measure rates of…

Populations and Evolution · Quantitative Biology 2015-05-13 Vitaly V. Ganusov , Jose Borghans , Rob De Boer

This paper is devoted to the development of adaptive control schemes for uncertain discrete-time systems, which guarantee robust, global, exponential convergence to the desired equilibrium point of the system. The proposed control scheme…

Optimization and Control · Mathematics 2015-09-02 Iasson Karafyllis , Maria Kontorinaki , Markos Papageorgiou

Chemotaxis systems play a crucial role in modeling the dynamics of bacterial and cellular behaviors, including propagation, aggregation, and pattern formation, all under the influence of chemical signals. One notable characteristic of these…

Numerical Analysis · Mathematics 2024-02-07 Alina Chertock , Shumo Cui , Alexander Kurganov , Chenxi Wang

In this paper we propose and analyze a finite difference numerical scheme for the Poisson-Nernst-Planck equation (PNP) system. To understand the energy structure of the PNP model, we make use of the Energetic Variational Approach (EnVarA),…

Numerical Analysis · Mathematics 2020-09-18 Chun Liu , Cheng Wang , Steven M. Wise , Xingye Yue , Shenggao Zhou

We study a PDE model for dynamics of susceptible-infected interactions. The dispersal of susceptibles is via diffusion and repellent taxis as they move away from the increasing density of infected. The diffusion of infected is a nonlinear,…

Analysis of PDEs · Mathematics 2019-02-07 Chiganga Samson Ruoja , Christina Surulescu , Anna Zhigun

We study a discrete denoising diffusion framework that integrates a sample-efficient estimator of single-site conditionals with round-robin noising and denoising dynamics for generative modeling over discrete state spaces. Rather than…

Machine Learning · Computer Science 2026-03-02 Karthik Elamvazhuthi , Abhijith Jayakumar , Andrey Y. Lokhov

The random diffusion model is a continuum model for a conserved scalar density field driven by diffusive dynamics where the bare diffusion coefficient is density dependent. We generalize the model from one with a sharp wavenumber cutoff to…

Soft Condensed Matter · Physics 2015-03-13 David D. McCowan , Gene F. Mazenko

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann