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Quantifying normative pediatric cranial development and suture ossification is crucial for diagnosing and treating growth-related cephalic disorders. Computed tomography (CT) is widely used to evaluate cranial and sutural deformities;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Krithika Iyer , Austin Tapp , Athelia Paulli , Gabrielle Dickerson , Syed Muhammad Anwar , Natasha Lepore , Marius George Linguraru

Accurate three-dimensional (3D) reconstruction of cardiac chamber motion from time-resolved medical imaging modalities is of growing interest in both the clinical and biomechanical fields. Despite recent advancement, the cardiac motion…

Medical Physics · Physics 2025-04-18 Francesco Capuano , Yue-Hin Loke , Ibrahim Yildiran , Laura Olivieri , Elias Balaras

Reconstructing high-quality magnetic resonance images (MRI) from undersampled raw data is of great interest from both technical and clinical point of views. To this date, however, it is still a mathematically and computationally challenging…

Numerical Analysis · Mathematics 2021-09-01 T. Schmoderer , A. I Aviles-Rivero , V. Corona , N. Debroux , C-B. Schönlieb

To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…

Purpose: This study assesses the effectiveness of Deep Learning (DL) for creating synthetic CT (sCT) images in MR-guided adaptive radiation therapy (MRgART). Methods: A Cycle-GAN model was trained with MRI and CT scan slices from MR-LINAC…

MR imaging will play a very important role in radiotherapy treatment planning for segmentation of tumor volumes and organs. However, the use of MR-based radiotherapy is limited because of the high cost and the increased use of metal…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Cheng-Bin Jin , Hakil Kim , Wonmo Jung , Seongsu Joo , Ensik Park , Ahn Young Saem , In Ho Han , Jae Il Lee , Xuenan Cui

A joint image reconstruction and segmentation approach based on disentangled representation learning was trained to enable cardiac cine MR imaging in real-time and under free-breathing. An exploratory feasibility study tested the proposed…

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao

Computed tomography (CT) has been a powerful diagnostic tool since its emergence in the 1970s. Using CT data, three-dimensional (3D) structures of human internal organs and tissues, such as blood vessels, can be reconstructed using…

Applications · Statistics 2024-04-01 Qianhan Zeng , Jing Zhou , Ying Ji , Hansheng Wang

In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Hajar Emami , Ming Dong , Siamak Nejad-Davarani , Carri Glide-Hurst

We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer…

Medical Physics · Physics 2026-01-27 Atharva Hans , Abhishek Singh , Pavlos Vlachos , Ilias Bilionis

Current approaches to in vivo imaging of the mouse central nervous system (CNS) do not offer a combination of micrometer resolution and a whole-brain field of view. To address this limitation, we introduce an approach based on synchrotron…

Spatial transcriptomics (ST) has emerged as a powerful technology for bridging histology imaging with gene expression profiling. However, its application has been limited by low throughput and the need for specialized experimental…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Tinglin Huang , Tianyu Liu , Mehrtash Babadi , Wengong Jin , Rex Ying

Limited-angle computed tomography (LACT) reconstruction is an inverse problem with severe ill-posedness arising from missing projection angles, and it is difficult to restore high-precision images without sufficient prior knowledge. In…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Hinako Isogai , Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

In this paper, a novel and robust algorithm is proposed for adaptive beamforming based on the idea of reconstructing the autocorrelation sequence (ACS) of a random process from a set of measured data. This is obtained from the first column…

Information Theory · Computer Science 2021-06-25 Saeed Mohammadzadeh , Vitor H. Nascimento , Rodrigo C. de Lamare , Osman Kukrer

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…

Medical Physics · Physics 2015-05-19 Xun Jia , Bin Dong , Yifei Lou , Steve B. Jiang

Transcranial focused ultrasound (tFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively and often under MRI guidance. CT imaging is used to estimate the acoustic properties that vary…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Benoit M. Dawant , Charles F. Caskey

Magnetic Resonance Spectroscopic Imaging (MRSI) is an essential tool for quantifying metabolites in the body, but the low spatial resolution limits its clinical applications. Deep learning-based super-resolution methods provided promising…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Siyuan Dong , Gilbert Hangel , Eric Z. Chen , Shanhui Sun , Wolfgang Bogner , Georg Widhalm , Chenyu You , John A. Onofrey , Robin de Graaf , James S. Duncan

Flow matching (FM) is a general framework for defining probability paths via Ordinary Differential Equations (ODEs) to transform between noise and data samples. Recent approaches attempt to straighten these flow trajectories to generate…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Ling Yang , Zixiang Zhang , Zhilong Zhang , Xingchao Liu , Minkai Xu , Wentao Zhang , Chenlin Meng , Stefano Ermon , Bin Cui