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The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

We propose Shallow Flow Matching (SFM), a novel mechanism that enhances flow matching (FM)-based text-to-speech (TTS) models within a coarse-to-fine generation paradigm. Unlike conventional FM modules, which use the coarse representations…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-24 Dong Yang , Yiyi Cai , Yuki Saito , Lixu Wang , Hiroshi Saruwatari

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jigang Duan , Genwei Ma , Xu Jiang , Wenfeng Xu , Ping Yang , Xing Zhao

Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone image registration, ultimately reducing patient radiation…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shaoyan Pan , Elham Abouei , Jacob Wynne , Tonghe Wang , Richard L. J. Qiu , Yuheng Li , Chih-Wei Chang , Junbo Peng , Justin Roper , Pretesh Patel , David S. Yu , Hui Mao , Xiaofeng Yang

Establishing accurate point-to-point correspondences between non-rigid 3D shapes remains a critical challenge, particularly under non-isometric deformations and topological noise. Existing functional map pipelines suffer from ambiguities…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Tianwei Ye , Xiaoguang Mei , Yifan Xia , Fan Fan , Jun Huang , Jiayi Ma

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Flow matching has recently emerged as a principled framework for learning continuous-time transport maps, enabling efficient ODE-based sampling without relying on stochastic diffusion processes. While generative modeling has shown promise…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Zhi Chen , Runze Hu , Le Zhang

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Conditional Flow Matching (CFM), a simulation-free method for training continuous normalizing flows, provides an efficient alternative to diffusion models for key tasks like image and video generation. The performance of CFM in solving…

Machine Learning · Computer Science 2026-03-17 Aram Davtyan , Leello Tadesse Dadi , Volkan Cevher , Paolo Favaro

Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Jiaxu Zheng , Zhenrong Shen , Lichi Zhang , Qun Chen

Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…

Medical Physics · Physics 2025-07-14 Hengyu Gao , Shaodong Ding , Ziyang Liu , Jiefu Zhang , Bolun Li , Zhiwu An , Li Wang , Jing Jing , Tao Liu , Yubo Fan , Zhongtao Hu

MRI provides superior soft tissue contrast without ionizing radiation; however, the absence of electron density information limits its direct use for dose calculation. As a result, current radiotherapy workflows rely on combined MRI and CT…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Zolnamar Dorjsembe , Hung-Yi Chen , Furen Xiao , Hsing-Kuo Pao

Objective: While recent advances in text-conditioned generative models have enabled the synthesis of realistic medical images, progress has been largely confined to 2D modalities such as chest X-rays. Extending text-to-image generation to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Daniele Molino , Camillo Maria Caruso , Filippo Ruffini , Paolo Soda , Valerio Guarrasi

We present Consistent-Recurrent Feature Flow Transformer (CRFT), a unified coarse-to-fine framework based on feature flow learning for robust cross-modal image registration. CRFT learns a modality-independent feature flow representation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Xuecong Liu , Mengzhu Ding , Zixuan Sun , Zhang Li , Xichao Teng

We present GaSpCT, a novel view synthesis and 3D scene representation method used to generate novel projection views for Computer Tomography (CT) scans. We adapt the Gaussian Splatting framework to enable novel view synthesis in CT based on…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Emmanouil Nikolakakis , Utkarsh Gupta , Jonathan Vengosh , Justin Bui , Razvan Marinescu

Synthetic electrocardiogram generation serves medical AI applications requiring privacy-preserving data sharing and training dataset augmentation. Current diffusion-based methods achieve high generation quality but require hundreds of…

Signal Processing · Electrical Eng. & Systems 2025-09-16 Vitalii Bondar , Serhii Semenov , Vira Babenko , Dmytro Holovniak

Flow matching (FM) learns vector fields by regressing stochastic velocity targets along intermediate distributions $p_t$. We identify a geometric optimization bottleneck in this regression problem: when the covariance $\Sigma_t$ of $p_t$ is…

Machine Learning · Computer Science 2026-05-14 Shadab Ahamed , Eshed Gal , Md Shahriar Rahim Siddiqui , Simon Ghyselincks , Moshe Eliasof , Eldad Haber

Learning 3D+t shape completion and generation from multi-view cardiac magnetic resonance (CMR) images requires a large amount of high-resolution 3D whole-heart segmentations (WHS) to capture shape priors. In this work, we leverage flow…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Qiang Ma , Qingjie Meng , Mengyun Qiao , Paul M. Matthews , Declan P. O'Regan , Wenjia Bai

Brain Magnetic Resonance Imaging (MRI) plays a central role in studying neurological development, aging, and diseases. One key application is Brain Age Prediction (BAP), which estimates an individual's biological brain age from MRI data.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Danilo Danese , Angela Lombardi , Matteo Attimonelli , Giuseppe Fasano , Tommaso Di Noia