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Class imbalance can often degrade predictive performance of supervised learning algorithms. Balanced classes can be obtained by oversampling exact copies, with noise, or interpolation between nearest neighbours (as in traditional SMOTE…

Machine Learning · Computer Science 2022-01-17 Emily Muller , Xu Zheng , Jer Hayes

Signal measurement appearing in the form of time series is one of the most common types of data used in medical machine learning applications. Such datasets are often small in size, expensive to collect and annotate, and might involve…

Machine Learning · Computer Science 2022-06-29 Xiaomin Li , Anne Hee Hiong Ngu , Vangelis Metsis

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

With the rising adoption of Machine Learning across the domains like banking, pharmaceutical, ed-tech, etc, it has become utmost important to adopt responsible AI methods to ensure models are not unfairly discriminating against any group.…

Machine Learning · Computer Science 2022-12-02 Bhushan Chaudhari , Himanshu Chaudhary , Aakash Agarwal , Kamna Meena , Tanmoy Bhowmik

The emergence of generative AI models has dramatically expanded the availability and use of synthetic data across scientific, industrial, and policy domains. While these developments open new possibilities for data analysis, they also raise…

Machine Learning · Statistics 2026-03-06 Ahmad Abdel-Azim , Ruoyu Wang , Xihong Lin

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

AI models present a wide range of applications in the field of medicine. However, achieving optimal performance requires access to extensive healthcare data, which is often not readily available. Furthermore, the imperative to preserve…

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

Electroencephalography (EEG) plays a significant role in the Brain Computer Interface (BCI) domain, due to its non-invasive nature, low cost, and ease of use, making it a highly desirable option for widespread adoption by the general…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Giulio Tosato , Cesare M. Dalbagno , Francesco Fumagalli

The generation of high-quality medical time series data is essential for advancing healthcare diagnostics and safeguarding patient privacy. Specifically, synthesizing realistic phonocardiogram (PCG) signals offers significant potential as a…

Machine Learning · Computer Science 2024-12-24 Ainaz Jamshidi , Muhammad Arif , Sabir Ali Kalhoro , Alexander Gelbukh

To address an emerging need for large number of diverse datasets for rigor evaluation of signal processing techniques, we developed and evaluated a new method for generating synthetic electrogastrogram time series. We used…

Signal Processing · Electrical Eng. & Systems 2024-05-09 Nadica Miljković , Nikola Milenić , Nenad B. Popović , Jaka Sodnik

Time series data are essential for a wide range of applications, particularly in developing robust machine learning models. However, access to high-quality datasets is often limited due to privacy concerns, acquisition costs, and labeling…

Machine Learning · Computer Science 2026-02-02 Jaime Vale , Vanessa Freitas Silva , Maria Eduarda Silva , Fernando Silva

Reliable seizure detection from electroencephalography (EEG) time series is a high-priority clinical goal, yet the acquisition cost and scarcity of labeled EEG data limit the performance of machine learning methods. This challenge is…

Methodology · Statistics 2026-01-30 Nina Moutonnet , Joshua Corneck , Felipe Tobar , Danilo Mandic

Analyzing data from past clinical trials is part of the ongoing effort to optimize the design, implementation, and execution of new clinical trials and more efficiently bring life-saving interventions to market. While there have been recent…

Machine Learning · Computer Science 2024-12-16 Chufan Gao , Mandis Beigi , Afrah Shafquat , Jacob Aptekar , Jimeng Sun

Synthetic data generation has emerged as a promising approach to address the challenges of using sensitive financial data in machine learning applications. By leveraging generative models, such as Generative Adversarial Networks (GANs) and…

Machine Learning · Computer Science 2025-10-31 James Meldrum , Basem Suleiman , Fethi Rabhi , Muhammad Johan Alibasa

The availability of large datasets is crucial for the development of new power system applications and tools; unfortunately, very few are publicly and freely available. We designed an end-to-end generative framework for the creation of…

Systems and Control · Electrical Eng. & Systems 2022-07-26 Andrea Pinceti , Lalitha Sankar , Oliver Kosut

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

Healthcare research and development face significant obstacles due to data scarcity and stringent privacy regulations, such as HIPAA and the GDPR, restricting access to essential real-world medical data. These limitations impede innovation,…

Machine Learning · Computer Science 2025-10-17 Md Ibrahim Shikder Mahin , Md Shamsul Arefin , Md Tanvir Hasan

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ishan Kumarasinghe , Dasuni Kawya , Madhura Edirisooriya , Isuri Devindi , Isuru Nawinne , Vajira Thambawita

Synthetic data generation creates data based on real-world data using generative models. In health applications, generating high-quality data while maintaining fairness for sensitive attributes is essential for equitable outcomes. Existing…

Machine Learning · Computer Science 2025-06-25 Nitish Nagesh , Ziyu Wang , Amir M. Rahmani