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Magnetic hyperthermia is an adjuvant therapy for cancer where injected magnetic nanoparticles are used to transfer energy from the time-dependent applied magnetic field into the surrounding medium. Its main importance is to be able to…

Soft Condensed Matter · Physics 2022-03-09 Zs. Iszaly , I. Gresits , I. G. Marian , Gy. Thuroczy , O. Sagi , B. G. Markus , F. Simon , I. Nandori

The main idea of magnetic hyperthermia is to increase locally the temperature of the human body by means of injected superparamagnetic nanoparticles. They absorb energy from a time-dependent external magnetic field and transfer it into…

Soft Condensed Matter · Physics 2021-09-27 Zs. Iszaly , I. G. Marian , I. A. Szabo , A. Trombettoni , I. Nandori

Single-domain ferromagnetic nanoparticle systems can be used to transfer energy from a time-dependent magnetic field into their environment. This local heat generation, i.e., magnetic hyperthermia, receives applications in cancer therapy…

Soft Condensed Matter · Physics 2018-08-02 Zs. Iszaly , K. Lovasz , I. Nagy , I. G. Marian , J. Racz , I. A. Szabo , L. Toth , N. F. Vas , V. Vekony , I. Nandori

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Tissues and Organs · Quantitative Biology 2016-11-09 Beatriz Sanz , M. Pilar Calatayud , Teobaldo E. Torres , Mónica L. Fanarraga , M. Ricardo Ibarra , Gerardo F. Goya

The deterministic Landau-Lifshitz-Gilbert equation has been used to investigate the nonlinear dynamics of magnetization and the specific loss power in magnetic nanoparticles with uniaxial anisotropy driven by a rotating magnetic field,…

Mesoscale and Nanoscale Physics · Physics 2012-12-13 I. Nandori , J. Racz

Magnetic fluid hyperthermia (MFH), the procedure of raising the temperature of tumor cells using magnetic nanoparticles (MNPs) as heating agents, has proven successful in treating some types of cancer. However, the low heating power…

Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…

Mesoscale and Nanoscale Physics · Physics 2014-03-26 Daniel B. Reeves , John B. Weaver

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

A linear combination of spherically symmetric heat sources is shown to provide optimal stationary thermal distribution in magnetic hyperthermia. Furthermore, such spatial location of heat sources produces suitable temperature distribution…

Applied Physics · Physics 2021-10-14 R. A. Rytov , V. A. Bautin , N. A. Usov

Magnetic nanoparticle-based hyperthermia has emerged as a promising therapeutic modality for treating malignant solid tumors that exhibit resistance to conventional cancer treatments, including chemotherapy and radiation. Despite the…

Mesoscale and Nanoscale Physics · Physics 2024-08-21 S. Scheibler , H. Wei , J. Ackers , S. Helbig , S. Koraltan , R. Peremadathil-Pradeep , M. Krupiński , M. Graeser , D. Suess , I. K. Herrmann , H. J. Hug

The use of engineered nanoscale magnetic materials in healthcare and biomedical technologies is rapidly growing. Two examples which have recently attracted significant attention are magnetic particle imaging (MPI) for biological monitoring,…

Nowadays, magnetic hyperthermia constitutes a complementary approach to cancer treatment. The use of magnetic particles as heating mediators, proposed in the 1950s, provides a novel strategy for improving tumor treatment and, consequently,…

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

Tissues and Organs · Quantitative Biology 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

The mechanism of magnetization reversal in single-domain ferromagnetic particles is of interest in many applications, in most of which losses must be minimized. In cancer therapy by hyperthermia the opposite requirement prevails: the…

Other Condensed Matter · Physics 2009-11-13 P. F. de Chatel , I. Nandori , J. Hakl , S. Meszaros , K. Vad

The deterministic Landau-Lifshitz-Gilbert equation has been used to investigate the nonlinear dynamics of magnetization and the specific loss power in magnetic nanoparticles with uniaxial anisotropy driven by a rotating magnetic field. We…

Mesoscale and Nanoscale Physics · Physics 2016-01-20 J. Racz , P. F. de Chatel , I. A. Szabo , L. Szunyogh , I. Nandori

Magnetosomes, i.e. nanoparticles synthesized in nature by magnetotactic bacteria, are very promising for use in magnetic hyperthermia for the cancer treatment. Using the solution of the stochastic Landau-Lifshitz equation we calculate the…

Applied Physics · Physics 2021-01-01 N. A. Usov , E. M. Gubanova

In the 21st century, new and alternative non-radioactive methods for cancer treatment have been developed. One of this is magnetic hyperthermia (MH), which is based on the ability of magnetic nanoparticles (MNP) to transduce electromagnetic…

Medical Physics · Physics 2020-07-28 Christian Calvache , Jenny Mera-Córdoba , Diego F. Coral

Magnetic particle hyperthermia, in which colloidal nanostructures are exposed to an alternating magnetic field, is a promising approach to cancer therapy. Unfortunately, the clinical efficacy of hyperthermia has not yet been optimized.…

This study was undertaken to develop a system for heat transfer simulation for optimization and treatment planning of magnetic hyperthermia treatment (MHT) using magnetic particle imaging (MPI). First, we performed phantom experiments to…

Medical Physics · Physics 2016-05-27 Natsuo Banura , Atsushi Mimura , Kohei Nishimoto , Kenya Murase

There are several methods to improve cancer patient survival rates by inducing hyperthermia in tumor tissues, which involves raising their temperature above 41{\deg}C. These methods utilize different energy sources to deliver heat to the…

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