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Related papers: On Using Large Language Models to Enhance Clinical…

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Objective: Allowing patients to access their own electronic health record (EHR) notes through online patient portals has the potential to improve patient-centered care. However, medical jargon, which abounds in EHR notes, has been shown to…

Computation and Language · Computer Science 2016-11-15 Jinying Chen , Abhyuday N. Jagannatha , Samah J. Jarad , Hong Yu

With the rapid advancement of Large Language Models (LLMs) and their outstanding performance in semantic and contextual comprehension, the potential of LLMs in specialized domains warrants exploration. This paper introduces the NoteAid EHR…

Computation and Language · Computer Science 2024-01-01 Xiaocheng Zhang , Zonghai Yao , Hong Yu

Identifying disease phenotypes from electronic health records (EHRs) is critical for numerous secondary uses. Manually encoding physician knowledge into rules is particularly challenging for rare diseases due to inadequate EHR coding,…

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Increasingly large electronic health records (EHRs) provide an opportunity to algorithmically learn medical knowledge. In one prominent example, a causal health knowledge graph could learn relationships between diseases and symptoms and…

Applications · Statistics 2019-10-04 Irene Y. Chen , Monica Agrawal , Steven Horng , David Sontag

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Retrieving information from EHR systems is essential for answering specific questions about patient journeys and improving the delivery of clinical care. Despite this fact, most EHR systems still rely on keyword-based searches. With the…

Computation and Language · Computer Science 2024-04-11 Shashi Kant Gupta , Aditya Basu , Bradley Taylor , Anai Kothari , Hrituraj Singh

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Large Language Models (LLMs) hold significant promise for improving clinical decision support and reducing physician burnout by synthesizing complex, longitudinal cancer Electronic Health Records (EHRs). However, their implementation in…

Computation and Language · Computer Science 2026-01-12 Dongchen Li , Jitao Liang , Wei Li , Xiaoyu Wang , Longbing Cao , Kun Yu

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…

Artificial Intelligence · Computer Science 2026-04-02 Xiao Yang , Xuejiao Zhao , Zhiqi Shen

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

The introduction of Large Language Models (LLMs) has advanced data representation and analysis, bringing significant progress in their use for medical questions and answering. Despite these advancements, integrating tabular data, especially…

Computation and Language · Computer Science 2024-09-23 Yanjun Gao , Skatje Myers , Shan Chen , Dmitriy Dligach , Timothy A Miller , Danielle Bitterman , Matthew Churpek , Majid Afshar

Background: One of the ways to enhance analyses conducted with large claims databases is by validating the measurement characteristics of code-based algorithms used to identify health outcomes or other key study parameters of interest.…

Physician burnout in the United States has reached critical levels, driven in part by the administrative burden of Electronic Health Record (EHR) documentation and complex diagnostic codes. To relieve this strain and maintain strict patient…

Information Retrieval · Computer Science 2026-03-25 Peter Hartnett , Chung-Chi Huang , Sarah Hartnett , David Hartnett