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We investigate parametric X-ray radiation (PXR) under condition of the extremely asymmetric diffraction, when the ultra-relativistic electron bunch is moving in \textit{vacuum} parallel to the crystal-vacuum interface, close to the crystal…

Accelerator Physics · Physics 2019-03-27 O. D. Skoromnik , I. D. Feranchuk , D. V. Lu

Prospects of parametric x-rays (PXR) application for the development of a tuneable quasi-monochromatic x-ray source for medical imaging are discussed. Analysis of basic requirements for electron accelerator shows that it must be relatively…

General Physics · Physics 2007-05-23 Alexander Lobko , Olga Lugovskaya

In oncology, treating cancer with a beam of photons is a well established therapeutic technique, developed over 100 years, and today over 50% of cancer patients will undergo traditional X-ray radiotherapy. However, ionizing radiation…

Medical Physics · Physics 2016-02-08 Mersini Makropoulou

Spectra of parametric X-ray radiation (PXR) are considered in the range of anomalous dispersion for one of the atoms in a crystal elementary cell. The PXR spectra are calculated both for the ultra-relativistic and non-relativistic electrons…

Materials Science · Physics 2007-05-23 I. D. Feranchuk , A. P. Ulyanenkov

Radiotherapy is used to treat cancer patients by damaging DNA of tumor cells using ionizing radiation. Photons are the most widely used radiation type for therapy, having been put into use soon after the first discovery of X-rays in 1895.…

Optimization and Control · Mathematics 2019-11-20 Roman Levin , Aleksandr Y. Aravkin , Minsun Kim

It is proposed to treat cancer by the combination of a strong magnetic field with intense ultrasound. At the low electrical conductivity of tissue the magnetic field is not frozen into the tissue, and oscillates against the tissue which is…

General Physics · Physics 2009-06-04 Dr. Friedwardt Winterberg

Achieving effective synergy between radiotherapy and immunotherapy is critical for optimizing tumor control and treatment outcomes. To explore the underlying mechanisms of this synergy, we have investigated a novel treatment approach known…

Quantitative Methods · Quantitative Biology 2025-04-23 Yixun Xing , Casey Moore , Debabrata Saha , Dan Nguyen , MaryLena Bleile , Xun Jia , Robert Timmerman , Hao Peng , Steve Jiang

External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Shane Farrar , Erik Leon

Nuclear magnetic resonance (NMR) diffusion measurements are widely used to derive parameters indirectly related to the microstructure of biological tissues and porous media. However, a direct imaging of cell or pore shapes and sizes would…

Medical Physics · Physics 2012-12-10 Tristan Anselm Kuder , Peter Bachert , Johannes Windschuh , Frederik Bernd Laun

Some clinical and pre-clinical data suggests that treating some tumors at a mild, patient-specific dose might delay resistance to treatment and increase survival time. A recent mathematical model with sensitive and resistant tumor cells…

Dynamical Systems · Mathematics 2022-12-01 Frank Alvarez , Yannick Viossat

Based on kinematic model of parametric X-ray Radiation (PXR), an approach for calculation of PXR characteristics (spectrum, intensity, polarization and yield) has been developed. The approach allows to take into account the beam divergence,…

Strongly Correlated Electrons · Physics 2016-08-31 A. P. Potylitsin

K-shell ionization and characteristic x-ray radiation (CXR) by high-energy electrons and positrons in oriented silicon crystals are studied using computer simulation. A method for this simulation has been developed and is described in…

Atomic Physics · Physics 2026-04-14 S. V. Trofymenko , I. V. Kyryllin

Blur in X-ray radiographs not only reduces the sharpness of image edges but also reduces the overall contrast. The effective blur in a radiograph is the combined effect of blur from multiple sources such as the detector panel, X-ray source…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 K. Aditya Mohan , Robert M. Panas , Jefferson A. Cuadra

Radiation therapy is one of the most common cancer treatments, and dose optimization and targeting of radiation are crucial since both cancerous and healthy cells are affected. Different mathematical and computational approaches have been…

Biological Physics · Physics 2025-11-07 Mirko Bagnarol , Gianluca Lattanzi , Jan Åström , Mikko Karttunen

It has long been known that radiation biology plays an important role and it is necessary for radiotherapy treatments. The radiation effects on normal and malignant tissues after exposure range from a femtosecond to months and years…

Medical Physics · Physics 2017-04-24 Cyril Voyant , Daniel Julian

Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation…

Instrumentation and Detectors · Physics 2009-11-06 C. Grupen

The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

Depolarization of circularly polarized light scattered from biological tissues depends on structural changes in cell nuclei, which can provide valuable information for differentiating cancer tissues concealed in healthy tissues. In this…

Medical Physics · Physics 2020-12-08 Nozomi Nishizawa , Bassam Al-Qadi , Takahiro Kuchimaru

Short single-walled carbon nanotubes (SWNTs) functionalized by PEGylated phospholipids are biologically non-toxic and long-circulating nanomaterials with intrinsic near infrared photoluminescence (NIR PL), characteristic Raman spectra, and…

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