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Quantum algorithms for simulating large and complex molecular systems are still in their infancy, and surpassing state-of-the-art classical techniques remains an ever-receding goal post. A promising avenue of inquiry in the meanwhile is to…

Quantum Physics · Physics 2025-08-07 Soohaeng Yoo Willow , D. ChangMo Yang , Chang Woo Myung

The emergence of quantum computing proposes a revolutionary paradigm that can radically transform numerous scientific and industrial application domains. The ability of quantum computers to scale computations exponentially imply better…

Software Engineering · Computer Science 2024-03-29 Vlad Stirbu , Tommi Mikkonen

Machine learning techniques have led to broad adoption of a statistical model of computing. The statistical distributions natively available on quantum processors are a superset of those available classically. Harnessing this attribute has…

As experimental quantum information processing (QIP) rapidly advances, an emerging challenge is to design a scalable architecture that combines various quantum elements into a complex device without compromising their performance. In…

Quantum Physics · Physics 2015-09-15 T. Brecht , W. Pfaff , C. Wang , Y. Chu , L. Frunzio , M. H. Devoret , R. J. Schoelkopf

A tight continuous relaxation is a crucial factor in solving mixed integer formulations of many NP-hard combinatorial optimization problems. The (weighted) max $k$-cut problem is a fundamental combinatorial optimization problem with…

Optimization and Control · Mathematics 2023-08-04 Ramin Fakhimi , Hamidreza Validi , Illya V. Hicks , Tamás Terlaky , Luis F. Zuluaga

Understanding how the D-Wave quantum computer could be used for machine learning problems is of growing interest. Our work evaluates the feasibility of using the D-Wave as a sampler for machine learning. We describe a hybrid system that…

Quantum Physics · Physics 2020-02-03 Jennifer Sleeman , John Dorband , Milton Halem

Quantum annealers are suited to solve several logistic optimization problems expressed in the QUBO formulation. However, the solutions proposed by the quantum annealers are generally not optimal, as thermal noise and other disturbing…

Quantum Physics · Physics 2024-05-21 Claudio Sanavio , Edoardo Tignone , Elisa Ercolessi

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

The necessary decarbonization efforts in energy sectors entail the integration of flexibility assets, as well as increased levels of uncertainty for the planning and operation of power systems. To cope with this in a cost-effective manner,…

Systems and Control · Electrical Eng. & Systems 2024-09-25 Stefan Borozan , Spyros Giannelos , Paola Falugi , Alexandre Moreira , Goran Strbac

In this paper, we propose a hybrid framework to solve large-scale permutation-based combinatorial problems effectively using a high-performance quadratic unconstrained binary optimization (QUBO) solver. To do so, transformations are…

Optimization and Control · Mathematics 2021-07-07 Siong Thye Goh , Sabrish Gopalakrishnan , Jianyuan Bo , Hoong Chuin Lau

Integer programming (IP) is an NP-hard combinatorial optimization problem that is widely used to represent a diverse set of real-world problems spanning multiple fields, such as finance, engineering, logistics, and operations research. It…

Quantum Physics · Physics 2025-08-20 Kapil Goswami , Peter Schmelcher , Rick Mukherjee

This paper surveys the trend of leveraging machine learning to solve mixed integer programming (MIP) problems. Theoretically, MIP is an NP-hard problem, and most of the combinatorial optimization (CO) problems can be formulated as the MIP.…

Artificial Intelligence · Computer Science 2022-03-08 Jiayi Zhang , Chang Liu , Junchi Yan , Xijun Li , Hui-Ling Zhen , Mingxuan Yuan

Decades of advances in mixed-integer linear programming (MILP) and recent development in mixed-integer second-order-cone programming (MISOCP) have translated very mildly to progresses in global solving nonconvex mixed-integer quadratically…

Optimization and Control · Mathematics 2018-11-21 Hongbo Dong , Yunqi Luo

Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti

We present BiqBin, an exact solver for linearly constrained binary quadratic problems. Our approach is based on an exact penalty method to first efficiently transform the original problem into an instance of Max-Cut, and then to solve the…

Optimization and Control · Mathematics 2022-08-15 Nicolò Gusmeroli , Timotej Hrga , Borut Lužar , Janez Povh , Melanie Siebenhofer , Angelika Wiegele

Quantum approximate optimization is one of the promising candidates for useful quantum computation, particularly in the context of finding approximate solutions to Quadratic Unconstrained Binary Optimization (QUBO) problems. However, the…

Mixed-integer optimization problems arise in a wide range of control applications. Benders decomposition is a widely used algorithm for solving such problems by decomposing them into a mixed-integer master problem and a continuous…

Optimization and Control · Mathematics 2026-04-07 Bernard T. Agyeman , Zhe Li , Ilias Mitrai , Prodromos Daoutidis

We present a hybrid classical/quantum algorithm for efficiently solving the eigenvalue problem of many-particle Hamiltonians on quantum computers with limited resources by splitting the workload between classical and quantum processors.…

Quantum Physics · Physics 2022-03-01 John P. T. Stenger , Daniel Gunlycke , C. Stephen Hellberg

Combinatorial optimization is one of the fields where near term quantum devices are being utilized with hybrid quantum-classical algorithms to demonstrate potentially practical applications of quantum computing. One of the most well studied…

Quantum Physics · Physics 2023-09-22 Anthony Angone , Xioayuan Liu , Ruslan Shaydulin , Ilya Safro

We investigate a hybrid quantum-classical solution method to the mean-variance portfolio optimization problems. Starting from real financial data statistics and following the principles of the Modern Portfolio Theory, we generate…

Quantum Physics · Physics 2019-07-01 Davide Venturelli , Alexei Kondratyev