Related papers: In-Vivo Training for Deep Brain Stimulation

Deep brain stimulation (DBS) is an established method for treating pathological conditions such as Parkinson's disease, dystonia, Tourette syndrome, and essential tremor. While the precise mechanisms which underly the effectiveness of DBS…

Deep Brain Stimulation (DBS) has gained increasing attention as an effective method to mitigate Parkinsons disease (PD) disorders. Existing DBS systems are open-loop such that the system parameters are not adjusted automatically based on…

At the group-level, deep brain stimulation leads to significant therapeutic benefit in a multitude of neurological and neuropsychiatric disorders. At the single-patient level, however, symptoms may sometimes persist despite "optimal"…

The ability to direct a Probabilistic Boolean Network (PBN) to a desired state is important to applications such as targeted therapeutics in cancer biology. Reinforcement Learning (RL) has been proposed as a framework that solves a…

Perceived outcomes from DBS for PD were sampled for 52 cases by surveying 46 DBS recipients and 45 carers. Post-DBS experience ranged from 10-129 months. There were significant variations in perceived outcomes over time. In some cases…

In this paper, we propose a principled deep reinforcement learning (RL) approach that is able to accelerate the convergence rate of general deep neural networks (DNNs). With our approach, a deep RL agent (synonym for optimizer in this work)…

This study considers multiple reconfigurable intelligent surfaces (RISs)-aided multiuser downlink systems with the goal of jointly optimizing the transmitter precoding and RIS phase shift matrix to maximize spectrum efficiency. Unlike prior…

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Reinforcement Learning (RL) has been widely used to solve tasks where the environment consistently provides a dense reward value. However, in real-world scenarios, rewards can often be poorly defined or sparse. Auxiliary signals are…

This paper presents a novel multi-agent reinforcement learning (RL) approach for personalized glucose control in individuals with type 1 diabetes (T1D). The method employs a closed-loop system consisting of a blood glucose (BG) metabolic…

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

In recent years, deep reinforcement learning (RL) has shown its effectiveness in solving complex continuous control tasks. However, this comes at the cost of an enormous amount of experience required for training, exacerbated by the…

Parkinson's disease (PD) is a progressive degenerative disorder of the central nervous system characterized by motor and non-motor symptoms. As the disease progresses, patients alternate periods in which motor symptoms are mitigated due to…

Training deep neural networks (DNNs) using traditional backpropagation (BP) presents challenges in terms of computational complexity and energy consumption, particularly for on-device learning where computational resources are limited.…

Deep Reinforcement Learning (DRL) underlies in a simulated environment and optimizes objective goals. By extending the conventional interaction scheme, this paper proffers gym-ds3, a scalable and reproducible open environment tailored for a…

In this paper we present an efficient model of the neuronal potentials recorded by a deep brain stimulation microelectrode (DBS MER) in the subthalamic nucleus. It is shown that a computationally efficient filtered point process consisting…

Reinforcement Learning (RL) can be used to fit a mapping from patient state to a medication regimen. Prior studies have used deterministic and value-based tabular learning to learn a propofol dose from an observed anesthetic state. Deep RL…

Several applications in the scientific simulation of physical systems can be formulated as control/optimization problems. The computational models for such systems generally contain hyperparameters, which control solution fidelity and…

Reinforcement learning has been increasingly applied in monitoring applications because of its ability to learn from previous experiences and can make adaptive decisions. However, existing machine learning-based health monitoring…

We study the joint active/passive beamforming and channel blocklength (CBL) allocation in a non-ideal reconfigurable intelligent surface (RIS)-aided ultra-reliable and low-latency communication (URLLC) system. The considered scenario is a…