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Accurate parsing of citations is necessary for machine-readable scholarly infrastructure. But, despite sustained interest in this problem, existing evaluation techniques are often not generalizable, based on synthetic data, or not publicly…

Digital Libraries · Computer Science 2026-03-27 Parth Sarin , Juan Pablo Alperin , Adam Buttrick , Dione Mentis

Deep research, in which an agent searches the open web, collects evidence, and derives an answer through extended reasoning, is a prominent use case for frontier language models. Frontier deep research products score high on existing…

Artificial Intelligence · Computer Science 2026-05-21 Sixiong Xie , Zhuofan Shi , Haiyang Shen , Jiuzheng Wang , Siqi Zhong , Mugeng Liu , Chongyang Pan , Peilun Jia , Baoqing Sun , Xiang Jing , Yun Ma

DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…

Biological Physics · Physics 2025-10-21 Wangwei Dong , Zezhou Liu , Ruiyao Liu , Deborah Kuchnir Fygenson , Walter Reisner

DNA data storage is rapidly emerging as a promising solution for long-term data archiving, largely due to its exceptional durability. However, the synthesis of DNA strands remains a significant bottleneck in terms of cost and speed. To…

Other Computer Science · Computer Science 2025-07-11 Parv Agarwal , Nimesh Pinnamaneni , Thomas Heinis

Neural Radiance Field (NeRF) research has attracted significant attention recently, with 3D modelling, virtual/augmented reality, and visual effects driving its application. While current NeRF implementations can produce high quality visual…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Adrian Azzarelli , Nantheera Anantrasirichai , David R Bull

High throughput sequencing of RNA (RNA-Seq) can provide us with millions of short fragments of RNA transcripts from a sample. How to better recover the original RNA transcripts from those fragments (RNA-Seq assembly) is still a difficult…

Genomics · Quantitative Biology 2019-02-15 Shunfu Mao , Yihan Jiang , Edwin Basil Mathew , Sreeram Kannan

Sequential structure is a key feature of multiple domains of natural cognition and behavior, such as language, movement and decision-making. Likewise, it is also a central property of tasks to which we would like to apply artificial…

Neurons and Cognition · Quantitative Biology 2026-01-01 Barna Zajzon , Younes Bouhadjar , Maxime Fabre , Felix Schmidt , Noah Ostendorf , Emre Neftci , Abigail Morrison , Renato Duarte

Molecular carriers represent an increasingly common strategy in the field of nanopore sensing to use secondary molecules to selectively report on the presence of target analytes in solution, allowing for sensitive assays of otherwise…

Biomolecules · Quantitative Biology 2023-05-10 Zachary Roelen , Vincent Tabard-Cossa

The acquisition of labels for supervised learning can be expensive. To improve the sample efficiency of neural network regression, we study active learning methods that adaptively select batches of unlabeled data for labeling. We present a…

Machine Learning · Statistics 2023-08-02 David Holzmüller , Viktor Zaverkin , Johannes Kästner , Ingo Steinwart

The explosive growth of various types of big data and advances in AI technologies have catalyzed a new type of workloads called multi-modal DNNs. Multi-modal DNNs are capable of interpreting and reasoning about information from multiple…

Reasoning is an essential capacity for large language models (LLMs) to address complex tasks, where the identification of process errors is vital for improving this ability. Recently, process-level reward models (PRMs) were proposed to…

Artificial Intelligence · Computer Science 2025-03-18 Zhaopan Xu , Pengfei Zhou , Jiaxin Ai , Wangbo Zhao , Kai Wang , Xiaojiang Peng , Wenqi Shao , Hongxun Yao , Kaipeng Zhang

Motivation: Illumina DNA sequencing is now the predominant source of raw genomic data, and data volumes are growing rapidly. Bioinformatic analysis pipelines are having trouble keeping pace. A common bottleneck in such pipelines is the…

Genomics · Quantitative Biology 2014-09-09 Gregory G. Faust , Ira M. Hall

Deep learning and large public datasets have recently catalyzed the proliferation of AI models for processing brain recordings. However, systematically evaluating these models remains a challenge: not only do the preprocessing pipelines,…

DNA sequence encoding is fundamental to gene function prediction, protein synthesis, and diverse downstream biological tasks. Despite the substantial progress achieved by large-scale DNA sequence pretraining, existing studies have…

Machine Learning · Computer Science 2026-04-21 Zhijiang Tang , Jiaxin Qi , Yan Cui , Jinli Ou , Yuhua Zheng , Jianqiang Huang

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Randomized benchmarking (RB) refers to a collection of protocols that in the past decade have become central methods for characterizing quantum gates. These protocols aim at efficiently estimating the quality of a set of quantum gates in a…

Quantum Physics · Physics 2022-06-20 Jonas Helsen , Ingo Roth , Emilio Onorati , Albert H. Werner , Jens Eisert

In this study, we examine the mechanism of nanopore-based DNA sequencing using a voltage bias across a graphene nanoribbon. Using density functional theory and a non-equilibrium Green's function approach, we determine the transmission…

Mesoscale and Nanoscale Physics · Physics 2018-09-11 Hannah L. McFarland , Towfiq Ahmed , Jian-Xin Zhu , Alexander V. Balatsky , Jason T. Haraldsen

Reliable and robust evaluation methods are a necessary first step towards developing machine learning models that are themselves robust and reliable. Unfortunately, current evaluation protocols typically used to assess classifiers fail to…

Machine Learning · Computer Science 2025-05-26 Michael W. Spratling

Benchmarking is crucial for testing and validating any system, even more so in real-time systems. Typical real-time applications adhere to well-understood abstractions: they exhibit a periodic behavior, operate on a well-defined working…

Software Engineering · Computer Science 2022-08-02 Mattia Nicolella , Shahin Roozkhosh , Denis Hoornaert , Andrea Bastoni , Renato Mancuso
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