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Diffusion models have found phenomenal success as expressive priors for solving inverse problems, but their extension beyond natural images to more structured scientific domains remains limited. Motivated by applications in materials…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Timofey Efimov , Harry Dong , Megna Shah , Jeff Simmons , Sean Donegan , Yuejie Chi

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Diffusion models have emerged as the new state-of-the-art generative model with high quality samples, with intriguing properties such as mode coverage and high flexibility. They have also been shown to be effective inverse problem solvers,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Hyungjin Chung , Dohoon Ryu , Michael T. McCann , Marc L. Klasky , Jong Chul Ye

Recently, diffusion model-based inverse problem solvers (DIS) have emerged as state-of-the-art approaches for addressing inverse problems, including image super-resolution, deblurring, inpainting, etc. However, their application to video…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Taesung Kwon , Jong Chul Ye

Diffusion models have become increasingly popular for generative modeling due to their ability to generate high-quality samples. This has unlocked exciting new possibilities for solving inverse problems, especially in image restoration and…

We propose self-diffusion, a novel framework for solving inverse problems without relying on pretrained generative models. Traditional diffusion-based approaches require training a model on a clean dataset to learn to reverse the forward…

Machine Learning · Computer Science 2025-12-09 Guanxiong Luo , Shoujin Huang , Yanlong Yang

Diffusion models have recently emerged as powerful generative priors for solving inverse problems. However, training diffusion models in the pixel space are both data-intensive and computationally demanding, which restricts their…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Bowen Song , Soo Min Kwon , Zecheng Zhang , Xinyu Hu , Qing Qu , Liyue Shen

Diffusion models can learn strong image priors from underlying data distribution and use them to solve inverse problems, but the training process is computationally expensive and requires lots of data. Such bottlenecks prevent most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Jason Hu , Bowen Song , Xiaojian Xu , Liyue Shen , Jeffrey A. Fessler

Score-based diffusion models achieve state-of-the-art performance for inverse problems, but their practical deployment is hindered by long inference times and cumbersome hyperparameter tuning. While pretrained diffusion models can be reused…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Julio Oscanoa , Irmak Sivgin , Cagan Alkan , Daniel Ennis , John Pauly , Mert Pilanci , Shreyas Vasanawala

Diffusion models have established new state of the art in a multitude of computer vision tasks, including image restoration. Diffusion-based inverse problem solvers generate reconstructions of exceptional visual quality from heavily…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Imaging inverse problems can be solved in an unsupervised manner using pre-trained diffusion models, but doing so requires approximating the gradient of the measurement-conditional score function in the diffusion reverse process. We show…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Matt C. Bendel , Saurav K. Shastri , Rizwan Ahmad , Philip Schniter

Diffusion models have become a popular approach for image generation and reconstruction due to their numerous advantages. However, most diffusion-based inverse problem-solving methods only deal with 2D images, and even recently published 3D…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Suhyeon Lee , Hyungjin Chung , Minyoung Park , Jonghyuk Park , Wi-Sun Ryu , Jong Chul Ye

Inverse problems are prevalent across various disciplines in science and engineering. In the field of computer vision, tasks such as inpainting, deblurring, and super-resolution are commonly formulated as inverse problems. Recently,…

Machine Learning · Computer Science 2025-01-07 Shayan Mohajer Hamidi , En-Hui Yang

Using diffusion priors to solve inverse problems in imaging have significantly matured over the years. In this chapter, we review the various different approaches that were proposed over the years. We categorize the approaches into the more…

Machine Learning · Computer Science 2025-08-05 Hyungjin Chung , Jeongsol Kim , Jong Chul Ye

Solving ill-posed inverse problems requires careful formulation of prior beliefs over the signals of interest and an accurate description of their manifestation into noisy measurements. Handcrafted signal priors based on e.g. sparsity are…

Machine Learning · Computer Science 2025-08-14 Tristan S. W. Stevens , Hans van Gorp , Faik C. Meral , Junseob Shin , Jason Yu , Jean-Luc Robert , Ruud J. G. van Sloun

Diffusion models are state-of-the-art generative models, yet their samples often fail to satisfy application objectives such as safety constraints or domain-specific validity. Existing techniques for alignment require gradients, internal…

Inverse problems are fundamental to science and engineering, where the goal is to infer an underlying signal or state from incomplete or noisy measurements. Recent approaches employ diffusion models as powerful implicit priors for such…

Machine Learning · Computer Science 2025-11-27 Bilal Ahmed , Joseph G. Makin

Diffusion models have emerged as a key pillar of foundation models in visual domains. One of their critical applications is to universally solve different downstream inverse tasks via a single diffusion prior without re-training for each…

Machine Learning · Computer Science 2023-10-03 Morteza Mardani , Jiaming Song , Jan Kautz , Arash Vahdat

Image restoration (IR) has been an indispensable and challenging task in the low-level vision field, which strives to improve the subjective quality of images distorted by various forms of degradation. Recently, the diffusion model has…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Xin Li , Yulin Ren , Xin Jin , Cuiling Lan , Xingrui Wang , Wenjun Zeng , Xinchao Wang , Zhibo Chen

Microstructure reconstruction, a major component of inverse computational materials engineering, is currently advancing at an unprecedented rate. While various training-based and training-free approaches are developed, the majority of…

Materials Science · Physics 2022-11-28 Christian Düreth , Paul Seibert , Dennis Rücker , Stephanie Handford , Markus Kästner , Maik Gude
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