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In this paper, we study the diffusability (learnability) of variational autoencoders (VAE) in latent diffusion. First, we show that pixel-space diffusion trained with an MSE objective is inherently biased toward learning low and mid spatial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Mang Ning , Mingxiao Li , Le Zhang , Lanmiao Liu , Matthew B. Blaschko , Albert Ali Salah , Itir Onal Ertugrul

Cross-modal retrieval is to utilize one modality as a query to retrieve data from another modality, which has become a popular topic in information retrieval, machine learning, and database. How to effectively measure the similarity between…

Information Retrieval · Computer Science 2021-12-07 Jiwei Zhang , Yi Yu , Suhua Tang , Jianming Wu , Wei Li

This paper presents a comprehensive study focused on disentangling hippocampal shape variations from diffusion tensor imaging (DTI) datasets within the context of neurological disorders. Leveraging a Mesh Variational Autoencoder (VAE)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Jakaria Rabbi , Johannes Kiechle , Christian Beaulieu , Nilanjan Ray , Dana Cobzas

The development of deep learning methods for magnetic resonance spectroscopy (MRS) is often hindered by limited availability of large, high-quality training datasets. While physics-based simulations are commonly used to mitigate this…

In this paper, we propose a novel model called Learnable VAE (L-VAE), which learns a disentangled representation together with the hyperparameters of the cost function. L-VAE can be considered as an extension of \b{eta}-VAE, wherein the…

Machine Learning · Computer Science 2025-07-04 Hazal Mogultay Ozcan , Sinan Kalkan , Fatos T. Yarman-Vural

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Large and well-annotated datasets are essential for advancing deep learning applications, however often costly or impossible to obtain by a single entity. In many areas, including the medical domain, approaches relying on data sharing have…

Machine Learning · Computer Science 2024-08-02 Francesco Di Salvo , David Tafler , Sebastian Doerrich , Christian Ledig

As deep Variational Auto-Encoder (VAE) frameworks become more widely used for modeling biomolecular simulation data, we emphasize the capability of the VAE architecture to concurrently maximize the timescale of the latent space while…

Chemical Physics · Physics 2021-12-08 Hannah K. Wayment-Steele , Vijay S. Pande

Automatic melody generation has been a long-time aspiration for both AI researchers and musicians. However, learning to generate euphonious melodies has turned out to be highly challenging. This paper introduces 1) a new variant of…

Artificial Intelligence · Computer Science 2018-11-02 Yu-An Wang , Yu-Kai Huang , Tzu-Chuan Lin , Shang-Yu Su , Yun-Nung Chen

Phytoplankton absorb and scatter light in unique ways, subtly altering the color of water, changes that are often minor for human eyes to detect but can be captured by sensitive ocean color instruments onboard satellites from space.…

Machine Learning · Computer Science 2025-04-21 Jiadong Lou , Bingqing Liu , Yuanheng Xiong , Xiaodong Zhang , Xu Yuan

Denoising-based diffusion transformers, despite their strong generation performance, suffer from inefficient training convergence. Existing methods addressing this issue, such as REPA (relying on external representation encoders) or SRA…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Mengmeng Wang , Dengyang Jiang , Liuzhuozheng Li , Yucheng Lin , Guojiang Shen , Xiangjie Kong , Yong Liu , Guang Dai , Jingdong Wang

Stochastic processes provide a mathematically elegant way model complex data. In theory, they provide flexible priors over function classes that can encode a wide range of interesting assumptions. In practice, however, efficient inference…

Machine Learning · Computer Science 2022-09-15 Swapnil Mishra , Seth Flaxman , Tresnia Berah , Harrison Zhu , Mikko Pakkanen , Samir Bhatt

Generative AI has received substantial attention in recent years due to its ability to synthesize data that closely resembles the original data source. While Generative Adversarial Networks (GANs) have provided innovative approaches for…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Xuan Xu , Saarthak Kapse , Rajarsi Gupta , Prateek Prasanna

Deep generative models have emerged as influential instruments for data generation and manipulation. Enhancing the controllability of these models by selectively modifying data attributes has been a recent focus. Variational Autoencoders…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Maxime Di Folco , Cosmin Bercea , Julia A. Schnabel

Our contribution is a unified cross-modality feature disentagling approach for multi-domain image translation and multiple organ segmentation. Using CT as the labeled source domain, our approach learns to segment multi-modal (T1-weighted…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Jue Jiang , Harini Veeraraghavan

The variational autoencoder (VAE) is a popular probabilistic generative model. However, one shortcoming of VAEs is that the latent variables cannot be discrete, which makes it difficult to generate data from different modes of a…

Machine Learning · Statistics 2017-11-21 Jay A. Hennig , Akash Umakantha , Ryan C. Williamson

Deep generative models have been demonstrated as problematic in the unsupervised out-of-distribution (OOD) detection task, where they tend to assign higher likelihoods to OOD samples. Previous studies on this issue are usually not…

Machine Learning · Computer Science 2024-01-04 Zezhen Zeng , Bin Liu

In this paper we tackle a fundamental question: "Can we train latent diffusion models together with the variational auto-encoder (VAE) tokenizer in an end-to-end manner?" Traditional deep-learning wisdom dictates that end-to-end training is…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Xingjian Leng , Jaskirat Singh , Yunzhong Hou , Zhenchang Xing , Saining Xie , Liang Zheng

The use of deep learning to undertake shape analysis of the complexities of the human head holds great promise. However, there have traditionally been a number of barriers to accurate modelling, especially when operating on both a global…

Vector Quantized-Variational AutoEncoders (VQ-VAE) are generative models based on discrete latent representations of the data, where inputs are mapped to a finite set of learned embeddings.To generate new samples, an autoregressive prior…

Machine Learning · Statistics 2022-08-04 Max Cohen , Guillaume Quispe , Sylvain Le Corff , Charles Ollion , Eric Moulines