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This paper presents an adaptive convolutional neural network (CNN) architecture that can automate diverse topology optimization (TO) problems having different underlying physics. The architecture uses the encoder-decoder networks with dense…

Computational Engineering, Finance, and Science · Computer Science 2025-09-10 Khaish Singh Chadha , Prabhat Kumar

Deep learning-based approaches, particularly graph neural networks (GNNs), have gained prominence in simulating flexible deformations and contacts of solids, due to their ability to handle unstructured physical fields and nonlinear…

Machine Learning · Computer Science 2026-04-07 Zhe Feng , Shilong Tao , Haonan Sun , Shaohan Chen , Zhanxing Zhu , Yunhuai Liu

In this paper, we introduce a novel method to interpret recurrent neural networks (RNNs), particularly long short-term memory networks (LSTMs) at the cellular level. We propose a systematic pipeline for interpreting individual hidden state…

Machine Learning · Computer Science 2018-09-12 Ramin M. Hasani , Alexander Amini , Mathias Lechner , Felix Naser , Radu Grosu , Daniela Rus

Mathematical theory shows us that multilayer feedforward Artificial Neural Networks(ANNs) are universal function approximators, capable of approximating any measurable function to any desired degree of accuracy. In practice designing…

Neural and Evolutionary Computing · Computer Science 2019-05-14 Philip Colangelo , Oren Segal , Alexander Speicher , Martin Margala

Fluid dynamics spans phenomena from the Cheerios effect to cosmic evolution and has been called the 'queen mother' of science. Traditional modelling relies on numerical methods, including finite differences, volumes, and elements, that…

Fluid Dynamics · Physics 2026-04-09 Kwame Agyei-Baah , Muhammad Rizwanur Rahman , E. R. Smith

Due to their intrinsic capabilities on parallel signal processing, optical neural networks (ONNs) have attracted extensive interests recently as a potential alternative to electronic artificial neural networks (ANNs) with reduced power…

Signal Processing · Electrical Eng. & Systems 2024-03-05 Yi-Feng Liu , Rui-Yao Ren , Dai-Bao Hou , Hai-Zhong Weng , Bo-Wen Wang , Ke-Jie Huang , Xing Lin , Feng Liu , Chen-Hui Li , Chao-Yuan Jin

In a previous paper, we have shown that a recurrent neural network (RNN) can be used to detect cellular network radio signal degradations accurately. We unexpectedly found, though, that accuracy gains diminished as we added layers to the…

Machine Learning · Computer Science 2024-04-18 David Mulvey , Chuan Heng Foh , Muhammad Ali Imran , Rahim Tafazolli

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

We show that deep convolutional neural networks (CNN) can massively outperform traditional densely-connected neural networks (both deep or shallow) in predicting eigenvalue problems in mechanics. In this sense, we strike out in a new…

Computational Physics · Physics 2018-07-19 David Finol , Yan Lu , Vijay Mahadevan , Ankit Srivastava

In this paper, we examine the strength of deep learning technique for diagnosing lung cancer on medical image analysis problem. Convolutional neural networks (CNNs) models become popular among the pattern recognition and computer vision…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Mehdi Fatan Serj , Bahram Lavi , Gabriela Hoff , Domenec Puig Valls

With the increased affordability and availability of whole-genome sequencing, large-scale and high-throughput gene expression is widely used to characterize diseases, including cancers. However, establishing specificity in cancer diagnosis…

Machine Learning · Statistics 2018-12-21 Xi Chen , Jin Xie , Qingcong Yuan

Deep learning, through the use of neural networks, has demonstrated remarkable ability to automate many routine tasks when presented with sufficient data for training. The neural network architecture (e.g. number of layers, types of layers,…

End-to-end learning of dynamical systems with black-box models, such as neural ordinary differential equations (ODEs), provides a flexible framework for learning dynamics from data without prescribing a mathematical model for the dynamics.…

Machine Learning · Statistics 2022-06-20 Paidamoyo Chapfuwa , Sherri Rose , Lawrence Carin , Edward Meeds , Ricardo Henao

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

Deep Neural Networks (DNNs) are widely used for decision making in a myriad of critical applications, ranging from medical to societal and even judicial. Given the importance of these decisions, it is crucial for us to be able to interpret…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Teddy Koker , Fatemehsadat Mireshghallah , Tom Titcombe , Georgios Kaissis

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

Model interpretability is a requirement in many applications in which crucial decisions are made by users relying on a model's outputs. The recent movement for "algorithmic fairness" also stipulates explainability, and therefore…

Machine Learning · Computer Science 2018-08-21 Xuan Liu , Xiaoguang Wang , Stan Matwin

Convolutional neural networks (CNNs) have been successfully used in a range of tasks. However, CNNs are often viewed as "black-box" and lack of interpretability. One main reason is due to the filter-class entanglement -- an intricate…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Haoyu Liang , Zhihao Ouyang , Yuyuan Zeng , Hang Su , Zihao He , Shu-Tao Xia , Jun Zhu , Bo Zhang

Deep learning techniques have recently demonstrated broad success in predicting complex dynamical systems ranging from turbulence to human speech, motivating broader questions about how neural networks encode and represent dynamical rules.…

Cellular Automata and Lattice Gases · Physics 2020-01-20 William Gilpin