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The ever-increasing data demand craves advancements in high-speed and energy-efficient computing hardware. Analog optical neural network (ONN) processors have emerged as a promising solution, offering benefits in bandwidth and energy…

Optics · Physics 2026-04-07 Chao Luan , Ronald Davis , Zaijun Chen , Dirk Englund , Ryan Hamerly

Systemic properties of living cells are the result of molecular dynamics governed by so-called genetic regulatory networks (GRN). These networks capture all possible features of cells and are responsible for the immense levels of adaptation…

Molecular Networks · Quantitative Biology 2015-06-04 Rudolf Hanel , Manfred Pöchacker , Manuel Schölling , Stefan Thurner

Deep Learning (DL) models are often black boxes, making their decision-making processes difficult to interpret. This lack of transparency has driven advancements in eXplainable Artificial Intelligence (XAI), a field dedicated to clarifying…

Machine Learning · Computer Science 2024-12-04 Adam Wróbel , Mikołaj Janusz , Bartosz Zieliński , Dawid Rymarczyk

Neural ordinary differential equations (NODE) have garnered significant attention for their design of continuous-depth neural networks and the ability to learn data/feature dynamics. However, for high-dimensional systems, estimating…

Machine Learning · Computer Science 2025-10-07 Muhao Guo , Haoran Li , Yang Weng

Charge carrier dynamics critically affect the efficiency and stability of organic photovoltaic devices, but they are challenging to model with traditional analytical methods. We introduce \b{eta}-Linearly Decoded Latent Ordinary…

Materials Science · Physics 2025-11-04 Li Raymond , Salim Flora , Wang Sijin , Wright Brendan

Recent work in deep learning focuses on solving physical systems in the Ordinary Differential Equation or Partial Differential Equation. This current work proposed a variant of Convolutional Neural Networks (CNNs) that can learn the hidden…

Machine Learning · Computer Science 2021-11-02 Mansura Habiba , Barak A. Pearlmutter

Single-cell RNA sequencing (scRNA-seq) technology provides high-throughput gene expression data to study the cellular heterogeneity and dynamics of complex organisms. Graph neural networks (GNNs) have been widely used for automatic cell…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Chenglin Li , Junni Zou , Dapeng Wu , Hongkai Xiong

We introduce two convolutional neural network (CNN) architectures, inspired by the Merriman-Bence-Osher (MBO) algorithm and by cellular automatons, to model and learn threshold dynamics for front evolution from video data. The first model,…

Machine Learning · Computer Science 2024-12-13 Elisa Negrini , Almanzo Jiahe Gao , Abigail Bowering , Wei Zhu , Luca Capogna

User response prediction makes a crucial contribution to the rapid development of online advertising system and recommendation system. The importance of learning feature interactions has been emphasized by many works. Many deep models are…

Information Retrieval · Computer Science 2019-04-30 Yi Yang , Baile Xu , Furao Shen , Jian Zhao

This paper proposes the Mesh Neural Network (MNN), a novel architecture which allows neurons to be connected in any topology, to efficiently route information. In MNNs, information is propagated between neurons throughout a state transition…

Machine Learning · Computer Science 2021-10-01 Federico A. Galatolo , Mario G. C. A. Cimino , Gigliola Vaglini

Representations for black-box optimisation methods (such as evolutionary algorithms) are traditionally constructed using a delicate manual process. This is in contrast to the representation that maps DNAs to phenotypes in biological…

Neural and Evolutionary Computing · Computer Science 2024-07-08 Milton L. Montero , Erwan Plantec , Eleni Nisioti , Joachim W. Pedersen , Sebastian Risi

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

Drawing inspiration from gradient-based meta-learning methods with infinitely small gradient steps, we introduce Continuous-Time Meta-Learning (COMLN), a meta-learning algorithm where adaptation follows the dynamics of a gradient vector…

Machine Learning · Computer Science 2022-03-04 Tristan Deleu , David Kanaa , Leo Feng , Giancarlo Kerg , Yoshua Bengio , Guillaume Lajoie , Pierre-Luc Bacon

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

Learning continuous-time dynamics on complex networks is crucial for understanding, predicting and controlling complex systems in science and engineering. However, this task is very challenging due to the combinatorial complexities in the…

Social and Information Networks · Computer Science 2020-06-19 Chengxi Zang , Fei Wang

Although data generation is often straightforward, extracting information from data is more difficult. Object-centric representation learning can extract information from images in an unsupervised manner. It does so by segmenting an image…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Joël Küchler , Ellen van Maren , Vaiva Vasiliauskaitė , Katarina Vulić , Reza Abbasi-Asl , Stephan J. Ihle

Neural Networks (GNNs) have revolutionized the molecular discovery to understand patterns and identify unknown features that can aid in predicting biophysical properties and protein-ligand interactions. However, current models typically…

Machine Learning · Computer Science 2022-12-21 Carter Knutson , Gihan Panapitiya , Rohith Varikoti , Neeraj Kumar

We report an in-silico demonstration of an all-optical cell classification system using a single-layer diffractive neural network (DNN) optimized for real-world biomedical images. Implemented virtually with a spatial light modulator (SLM),…

Computational models that predict cellular phenotypic responses to chemical and genetic perturbations can accelerate drug discovery by prioritizing therapeutic hypotheses and reducing costly wet-lab iteration. However, extracting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Pin-Jui Huang , Yu-Hsuan Liao , SooHeon Kim , NoSeong Park , JongBae Park , DongMyung Shin

Self-Organized Operational Neural Networks (Self-ONNs) have recently been proposed as new-generation neural network models with nonlinear learning units, i.e., the generative neurons that yield an elegant level of diversity; however, like…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Serkan Kiranyaz , Junaid Malik , Mehmet Yamac , Mert Duman , Ilke Adalioglu , Esin Guldogan , Turker Ince , Moncef Gabbouj