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The convergence of IoT, Edge, Cloud, and HPC technologies creates a compute continuum that merges cloud scalability and flexibility with HPC's computational power and specialized optimizations. However, integrating cloud and HPC resources…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-20 Aasish Kumar Sharma , Christian Boehme , Patrick Gelß , Ramin Yahyapour , Julian Kunkel

Large language models now serve millions of users daily, with providers incurring costs exceeding $700,000 per day. Each request requires token-by-token inference, making GPU scheduling central to latency, capacity, and cost. The difficulty…

Machine Learning · Computer Science 2026-05-18 Ruicheng Ao , Gan Luo , David Simchi-Levi , Xinshang Wang

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Real-time prediction of clinical interventions remains a challenge within intensive care units (ICUs). This task is complicated by data sources that are noisy, sparse, heterogeneous and outcomes that are imbalanced. In this paper, we…

Machine Learning · Computer Science 2017-05-25 Harini Suresh , Nathan Hunt , Alistair Johnson , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Continuous monitoring and patient acuity assessments are key aspects of Intensive Care Unit (ICU) practice, but both are limited by time constraints imposed on healthcare providers. Moreover, anticipating clinical trajectories remains…

Spatiotemporal data consisting of timestamps, GPS coordinates, and IDs occurs in many settings. Modeling approaches for this type of data must address challenges in terms of sensor noise, uneven sampling rates, and non-persistent IDs. In…

Methodology · Statistics 2024-10-10 Pranay Pherwani , Nicholas Hass , Anna K. Yanchenko

The rapid adoption of large language models (LLMs) has created significant challenges for efficient inference at scale. Unlike traditional workloads, LLM inference is constrained by both computation and the memory overhead of key-value (KV)…

Machine Learning · Computer Science 2026-05-07 Chengyi Nie , Nian Si , Zijie Zhou

We study the nurse staffing problem under random nurse demand and absenteeism. While the demand uncertainty is exogenous (stemming from the random patient census), the absenteeism uncertainty is \emph{endogenous}, i.e., the number of nurses…

Optimization and Control · Mathematics 2022-08-11 Minseok Ryu , Ruiwei Jiang

Generation expansion planning (GEP) models have been useful aids for long-term planning. Recent growth in intermittent renewable generation has increased the need to represent the capability for non-renewables to respond to rapid changes in…

Optimization and Control · Mathematics 2025-08-08 Hassan Shavandi , Mehrdad Pirnia , J. David Fuller

The rapid development of cloud-native architecture has promoted the widespread application of container technology, but the optimization problems in container scheduling and resource management still face many challenges. This paper…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-24 Xiaoye Wang

Deep learning models have achieved expert-level performance in healthcare with an exclusive focus on training accurate models. However, in many clinical environments such as intensive care unit (ICU), real-time model serving is equally if…

Machine Learning · Computer Science 2020-08-11 Shenda Hong , Yanbo Xu , Alind Khare , Satria Priambada , Kevin Maher , Alaa Aljiffry , Jimeng Sun , Alexey Tumanov

Clinician burnout poses a substantial threat to patient safety, particularly in high-acuity intensive care units (ICUs). Existing research predominantly relies on retrospective survey tools or broad electronic health record (EHR) metadata,…

Computation and Language · Computer Science 2025-09-08 Syed Ahmad Chan Bukhari , Fazel Keshtkar , Alyssa Meczkowska

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

Machine Learning · Computer Science 2021-02-25 Emma Rocheteau , Pietro Liò , Stephanie Hyland

Mobile edge computing (MEC) is one of the promising solutions to process computational-intensive tasks within short latency for emerging Internet-of-Things (IoT) use cases, e.g., virtual reality (VR), augmented reality (AR), autonomous…

Networking and Internet Architecture · Computer Science 2020-02-13 Jianhui Liu , Qi Zhang

Purpose: Summarize ICU delirium prediction models published within the past five years. Methods: Electronic searches were conducted in April 2019 using PubMed, Embase, Cochrane Central, Web of Science, and CINAHL to identify peer reviewed…

Intensive care units (ICUs) are complex and data-rich environments. Data routinely collected in the ICUs provides tremendous opportunities for machine learning, but their use comes with significant challenges. Complex problems may require…

Human-Computer Interaction · Computer Science 2024-06-05 Marceli Wac , Raul Santos-Rodriguez , Chris McWilliams , Christopher Bourdeaux

Heart attack remain one of the greatest contributors to mortality in the United States and globally. Patients admitted to the intensive care unit (ICU) with diagnosed heart attack (myocardial infarction or MI) are at higher risk of death.…

Machine Learning · Computer Science 2023-05-11 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Assessing acute brain dysfunction (ABD), including delirium and coma in the intensive care unit (ICU), is a critical challenge due to its prevalence and severe implications for patient outcomes. Current diagnostic methods rely on infrequent…

Continuous Integration and Continuous Deployment (CI/CD) pipelines are central to modern software development. In large organizations, the high volume of builds and tests creates bottlenecks, especially under shared infrastructure. This…

Software Engineering · Computer Science 2025-04-29 Grégory Bournassenko
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