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Quantitative magnetization transfer (MT) imaging enables non-invasive characterization of the macromolecular environment of tissues. However, recent work has highlighted that the quantification of MT parameters exhibits orientation…

Medical Physics · Physics 2025-10-06 Zijian Gao , Ziqiang Yu , Ziqin Zhou , Jian Hou , Baiyan Jiang , Michael Ong , Weitian Chen

Purpose: Magnetization transfer (MT) and inhomogeneous MT (ihMT) contrasts are used in MRI to provide information about macromolecular tissue content. In particular, MT is sensitive to macromolecules and ihMT appears to be specific to…

Purpose: Recent studies have shown that spin-lock MRI can simplify quantitative magnetization transfer (MT) by eliminating its dependency on water pool parameters, removing the need for a T1 map in macromolecular proton fraction (MPF)…

Since the inception of magnetization transfer (MT) imaging, it has been widely assumed that Henkelman's two spin pools have similar longitudinal relaxation times, which motivated many researchers to constrain them to each other. However,…

Purpose: Imaging biomarkers with increased myelin specificity are needed to better understand the complex progression of neurological disorders. Inhomogeneous magnetization transfer (ihMT) imaging is an emergent technique that has a high…

Purpose: To identify the predominant source of the $T_1$ variability described in the literature, which ranges from 0.6-1.1 s for brain white matter at 3 T. Methods: 25 $T_1$-mapping methods from the literature were simulated with a…

Medical Physics · Physics 2025-01-07 Jakob Assländer

At hybrid analog-digital (HAD) transceiver, an improved HAD rotational invariance techniques (ESPRIT), called I-HAD-ESPRIT, is proposed to measure the direction of arrival (DOA) of desired user, where the phase ambiguity due to HAD…

Information Theory · Computer Science 2018-12-04 Feng Shu , Ling Xu , Jinyong Lin , Jingsong Hu , Lingqing Gui , Jun Li , Jiangzhou Wang

A new method of measuring long spin-lattice relaxation times ($T_1$) is proposed. Being a single scan technique, the method is at least one order of magnitude faster than the conventional technique. This method (Single-Scan or Slice…

Soft Condensed Matter · Physics 2007-05-23 Rangeet Bhattacharyya , Anil Kumar

The NMR relaxation rate $1/T_{1}$ is studied for one-dimensional multicomponent spin-orbital systems. By combining the bosonization techniques and the exact solution of the SU($n$) model, we evaluate the power-law exponent and the…

Strongly Correlated Electrons · Physics 2015-06-24 Akira Kawaguchi , Tatsuya Fujii , Norio Kawakami

While typical qualitative T1-weighted magnetic resonance images reflect scanner and protocol differences, quantitative T1 mapping aims to measure T1 independent of these effects. Changes in T1 in the brain reflect structural changes in…

Objective: To develop an accurate myocardial T1 mapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition. Approach: The proposed T1 mapping technique (mIR-rt)…

Medical Physics · Physics 2025-08-29 Linqi Ge , Yihang Zhang , Huibin Zhu , Lang Zhang , Yihang Zhou , Haifeng Wang , Dong Liang , Hairong Zheng , Yanjie Zhu

Spin-lattice relaxation time ($T_1$) is an important biomarker in cardiac parametric mapping for characterizing myocardial tissue and diagnosing cardiomyopathies. Conventional Modified Look-Locker Inversion Recovery (MOLLI) acquires 11…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Nuno Capitão , Yi Zhang , Yidong Zhao , Qian Tao

Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at 7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration. Theory and Methods: Spoiled gradient echoes can be used to…

Medical Physics · Physics 2020-01-28 H. Olsson , M. Andersen , R. Wirestam , J. Lätt , G. Helms

In radial fast spin-echo MRI, a set of overlapping spokes with an inconsistent T2 weighting is acquired, which results in an averaged image contrast when employing conventional image reconstruction techniques. This work demonstrates that…

Medical Physics · Physics 2016-03-02 Kai Tobias Block , Martin Uecker , Jens Frahm

Purpose: Magnetization transfer (MT) has been identified as the principal source of $T_1$ variability in the MRI literature. This study assesses the sensitivity of established $T_1$ mapping techniques to variations in the underlying MT…

Medical Physics · Physics 2025-12-15 Jakob Assländer

Quantitative magnetic resonance (MR) T1\r{ho} mapping is a promising approach for characterizing intrinsic tissue-dependent information. However, long scan time significantly hinders its widespread applications. Recently, low-rank tensor…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Yuanyuan Liu , Dong Liang , Zhuo-Xu Cui , Yuxin Yang , Chentao Cao , Qingyong Zhu , Jing Cheng , Caiyun Shi , Haifeng Wang , Yanjie Zhu

The translational-diffusion coefficient $D_T$ and the spin-rotation contribution to the $^1$H NMR relaxation time $T_{1J}$ for methane (CH$_4$) are investigated using MD (molecular dynamics) simulations, over a wide range of densities…

Chemical Physics · Physics 2018-06-13 Philip M. Singer , D. Asthagiri , Walter G. Chapman , George J. Hirasaki

We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…

Background: Magnetization transfer (MT) saturation reflects the additional saturation of the MRI signal imposed by an MT pulse and is largely driven by the saturation of the bound pool. This reduction of the bound polarization by the MT…

Medical Physics · Physics 2021-05-03 Gunther Helms , Nikolaus Weiskopf , Antoine Lutti

We present the results of a muon-spin relaxation (muSR) investigation into magnetic ordering in several families of layered quasi-two-dimensional molecular antiferromagnets based on transition metal ions such as S=1/2 Cu2+ bridged with…

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